Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 2 results

2B8V
DownloadVisualize
BU of 2b8v by Molmil
Crystal structure of human Beta-secretase complexed with L-L000430,469
Descriptor: 3-BENZOYL-N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZAMIDE, Beta-secretase 1
Authors:Stachel, S.J, Coburn, C.A, Steele, T.G, Crouthamel, M.-C, Pietrak, B.L, Lai, M.-T, Holloway, M.K, Munshi, S.K, Graham, S.L, Vacca, J.P.
Deposit date:2005-10-10
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformationally biased P3 amide replacements of beta-secretase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
1NPA
DownloadVisualize
BU of 1npa by Molmil
crystal structure of HIV-1 protease-hup
Descriptor: (3S)-TETRAHYDROFURAN-3-YL (1R,2S)-3-[4-((1R)-2-{[(S)-AMINO(HYDROXY)METHYL]OXY}-2,3-DIHYDRO-1H-INDEN-1-YL)-2-BENZYL-3-OXOPYRROLIDIN-2-YL]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, POL polyprotein
Authors:Smith III, A.B, Hirschmann, R, Pasternak, A, Yao, W, Sprengeler, P.A, Holloway, M.K, Kuo, L.C, Chen, Z, Darke, P.L, Schleif, W.A.
Deposit date:2003-01-17
Release date:2004-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex.
J.MED.CHEM., 40, 1997

222036

PDB entries from 2024-07-03

PDB statisticsPDBj update infoContact PDBjnumon