1U8R
| Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions | Descriptor: | COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ... | Authors: | Wisedchaisri, G, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2004-08-06 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions. J.Mol.Biol., 342, 2004
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2A0S
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2BH1
| X-ray structure of the general secretion pathway complex of the N- terminal domain of EpsE and the cytosolic domain of EpsL of Vibrio cholerae | Descriptor: | CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN E,, GENERAL SECRETION PATHWAY PROTEIN L | Authors: | Abendroth, J, Murphy, P.M, Mushtaq, A, Bagdasarian, M, Sandkvist, M, Hol, W.G.J. | Deposit date: | 2005-01-06 | Release date: | 2005-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The X-Ray Structure of the Type II Secretion System Complex Formed by the N-Terminal Domain of Epse and the Cytoplasmic Domain of Epsl of Vibrio Cholerae J.Mol.Biol., 348, 2005
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2BTM
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2AF6
| Crystal structure of Mycobacterium tuberculosis Flavin dependent thymidylate synthase (Mtb ThyX) in the presence of co-factor FAD and substrate analog 5-Bromo-2'-Deoxyuridine-5'-Monophosphate (BrdUMP) | Descriptor: | 5-BROMO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Sampathkumar, P, Turley, S, Ulmer, J.E, Rhie, H.G, Sibley, C.H, Hol, W.G. | Deposit date: | 2005-07-25 | Release date: | 2005-10-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of the Mycobacterium tuberculosis Flavin Dependent Thymidylate Synthase (MtbThyX) at 2.0A Resolution. J.Mol.Biol., 352, 2005
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2B94
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2A0K
| Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.8 A resolution | Descriptor: | GLYCEROL, Nucleoside 2-deoxyribosyltransferase, SULFATE ION | Authors: | Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | Deposit date: | 2005-06-16 | Release date: | 2005-07-26 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J.Med.Chem., 49, 2006
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2A0U
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2B51
| Structural Basis for UTP Specificity of RNA Editing TUTases from Trypanosoma Brucei | Descriptor: | MANGANESE (II) ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE | Authors: | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | Deposit date: | 2005-09-27 | Release date: | 2005-11-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei. Embo J., 24, 2005
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1ZLJ
| Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR C-terminal Domain | Descriptor: | Dormancy Survival Regulator | Authors: | Wisedchaisri, G, Wu, M, Rice, A.E, Roberts, D.M, Sherman, D.R, Hol, W.G.J. | Deposit date: | 2005-05-06 | Release date: | 2006-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latency. J.Mol.Biol., 354, 2005
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1TII
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2B30
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2B4V
| Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei | Descriptor: | POTASSIUM ION, RNA editing complex protein MP57 | Authors: | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | Deposit date: | 2005-09-26 | Release date: | 2005-11-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei. Embo J., 24, 2005
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2B56
| Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei | Descriptor: | MAGNESIUM ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE, ... | Authors: | Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G. | Deposit date: | 2005-09-27 | Release date: | 2005-11-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei. Embo J., 24, 2005
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2DTR
| STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR | Descriptor: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | Authors: | Qiu, X, Pohl, E, Hol, W.G. | Deposit date: | 1996-07-26 | Release date: | 1997-08-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor. Biochemistry, 35, 1996
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1LT4
| HEAT-LABILE ENTEROTOXIN MUTANT S63K | Descriptor: | HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Van Den Akker, F, Hol, W.G.J. | Deposit date: | 1997-04-14 | Release date: | 1997-06-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant. Protein Sci., 6, 1997
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1QCB
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1DPB
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1QB5
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1EAF
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1QS0
| Crystal Structure of Pseudomonas Putida 2-oxoisovalerate Dehydrogenase (Branched-Chain Alpha-Keto Acid Dehydrogenase, E1B) | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, 2-OXOISOVALERATE DEHYDROGENASE ALPHA-SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA-SUBUNIT, ... | Authors: | Aevarsson, A, Seger, K, Turley, S, Sokatch, J.R, Hol, W.G.J. | Deposit date: | 1999-06-24 | Release date: | 1999-08-18 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes. Nat.Struct.Biol., 6, 1999
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1EFI
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1DPD
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1R49
| Human topoisomerase I (Topo70) double mutant K532R/Y723F | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(P*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', DNA topoisomerase I | Authors: | Interthal, H, Quigley, P.M, Hol, W.G, Champoux, J.J. | Deposit date: | 2003-10-03 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.13 Å) | Cite: | The role of lysine 532 in the catalytic mechanism of human topoisomerase I. J.Biol.Chem., 279, 2004
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1DPC
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