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PDB: 300 件
3FU1
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Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio cholerae
分子名称: CALCIUM ION, General secretion pathway protein G, ZINC ION
著者Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
登録日2009-01-13
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
3GN9
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Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio vulnificus
分子名称: CALCIUM ION, D-MALATE, Type II secretory pathway, ...
著者Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
登録日2009-03-16
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
2SBT
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A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO
分子名称: ACETONE, SUBTILISIN NOVO
著者Drenth, J, Hol, W.G.J, Jansonius, J.N, Koekoek, R.
登録日1976-09-07
公開日1976-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.
Cold Spring Harbor Symp.Quant.Biol., 36, 1972
3G20
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Crystal structure of the major pseudopilin from the type 2 secretion system of enterohaemorrhagic Escherichia coli
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
登録日2009-01-30
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
3CHB
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHOLERA TOXIN, UNKNOWN ATOM OR ION, ...
著者Merritt, E.A, Hol, W.G.J.
登録日1998-03-24
公開日1998-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.
J.Mol.Biol., 282, 1998
2A5F
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Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6
分子名称: ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ...
著者O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J.
登録日2005-06-30
公開日2005-08-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
4IDL
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Low melting temperature Anti-Cholera Toxin Llama VHH domain
分子名称: Single Domain Antibody VHH A9
著者Legler, P.M, Lam, A, Hol, W.G.J.
登録日2012-12-12
公開日2013-02-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure of a low-melting-temperature anti-cholera toxin: llama V(H)H domain.
Acta Crystallogr.,Sect.F, 69, 2013
4J76
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Crystal Structure of a parasite tRNA synthetase, ligand-free
分子名称: GLYCEROL, Tryptophanyl-tRNA synthetase
著者Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2013-02-12
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
4J75
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Crystal Structure of a parasite tRNA synthetase, product-bound
分子名称: GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
著者Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2013-02-12
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
4LK4
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Structure of Vibrio cholerae VesB protease
分子名称: VESB protease
著者Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
登録日2013-07-05
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional and Structural Characterization of Vibrio cholerae Extracellular Serine Protease B, VesB.
J.Biol.Chem., 289, 2014
4JTM
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Structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli
分子名称: Type II secretion system protein D
著者Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
登録日2013-03-23
公開日2013-07-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献A dodecameric ring-like structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli.
J.Struct.Biol., 18, 2013
2QV8
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Structure of the minor pseudopilin EpsH from the Type 2 Secretion System of Vibrio cholerae
分子名称: General secretion pathway protein H
著者Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
登録日2007-08-07
公開日2008-02-26
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the minor pseudopilin EpsH from the Type 2 secretion system of Vibrio cholerae.
J.Mol.Biol., 377, 2008
2TEC
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BU of 2tec by Molmil
MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT
分子名称: CALCIUM ION, EGLIN C, THERMITASE
著者Gros, P, Betzel, C, Dauter, Z, Wilson, K.S, Hol, W.G.J.
登録日1990-10-26
公開日1992-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content.
J.Mol.Biol., 210, 1989
5V49
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
分子名称: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
著者Barros-Alvarez, X, Hol, W.G.J.
登録日2017-03-08
公開日2017-07-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
2VMB
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BU of 2vmb by Molmil
The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
分子名称: CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN F
著者Abendroth, J, Korotkov, K.V, Mitchell, D.D, Kreger, A, Hol, W.G.J.
登録日2008-01-25
公開日2009-02-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae.
J.Struct.Biol., 166, 2009
2VMA
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The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
分子名称: CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN F, IODIDE ION
著者Abendroth, J, Korotkov, K.V, Mitchell, D.D, Kreger, A, Hol, W.G.J.
登録日2008-01-25
公開日2009-02-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae.
J.Struct.Biol., 166, 2009
5USF
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Leishmania donovani tyrosyl-tRNA synthetase in complex with nanobody and inhibitor
分子名称: 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Immunoglobulin heavy chain variable region, Tyrosyl-tRNA synthetase, ...
著者Barros-Alvarez, X, Hol, W.G.J.
登録日2017-02-13
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.
Biochimie, 138, 2017
2RET
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BU of 2ret by Molmil
The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus
分子名称: CHLORIDE ION, EpsJ, Pseudopilin EpsI, ...
著者Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
登録日2007-09-27
公開日2008-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus.
J.Mol.Biol., 375, 2008
3C3W
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Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR
分子名称: SULFATE ION, TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR
著者Wisedchaisri, G, Wu, M, Sherman, D.R, Hol, W.G.J.
登録日2008-01-28
公開日2008-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation
J.Mol.Biol., 378, 2008
3CVL
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphofructokinase (PFK) PTS1 peptide
分子名称: Peroxisome targeting signal 1 receptor PEX5, T. brucei PFK PTS1 peptide Ac-HEELAKL
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-18
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
3CVQ
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (7-SKL)
分子名称: GLYCEROL, PTS1 peptide 7-SKL (Ac-SNRWSKL), Peroxisome targeting signal 1 receptor PEX5
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-18
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
2CHB
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
分子名称: CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Merritt, E.A, Hol, W.G.J.
登録日1997-06-03
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
3CI0
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The Crystal Structure of the GspK-GspI-GspJ complex from enterotoxigenic Escherichia coli Type 2 Secretion System
分子名称: CALCIUM ION, CHLORIDE ION, Pseudopilin GspI, ...
著者Korotkov, K.V, Hol, W.G.J.
登録日2008-03-10
公開日2008-04-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the GspK-GspI-GspJ complex from the enterotoxigenic Escherichia coli type 2 secretion system.
Nat.Struct.Mol.Biol., 15, 2008
3CVP
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to PTS1 peptide (10-SKL)
分子名称: 10-SKL PTS1 peptide Ac-GTLSNRASKL, Peroxisome targeting signal 1 receptor PEX5
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-18
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008
3CVN
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Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) PTS1 peptide
分子名称: 1,2-ETHANEDIOL, Peroxisome targeting signal 1 receptor, T. brucei GAPDH PTS1 peptide Ac-DRDAAKL
著者Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J.
登録日2008-04-18
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
J.Mol.Biol., 381, 2008

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