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PDB: 311 件
1IIG
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STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE
分子名称: 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J.
登録日2001-04-23
公開日2001-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
1IIH
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STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHOGLYCERATE
分子名称: 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J.
登録日2001-04-23
公開日2001-05-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
1JVZ
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Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid
分子名称: 7BETA-(4CARBOXYBUTANAMIDO) CEPHALOSPORANIC ACID, cephalosporin acylase alpha chain, cephalosporin acylase beta chain
著者Kim, Y, Hol, W.G.J.
登録日2001-09-01
公開日2002-09-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity
CHEM.BIOL., 8, 2001
1JW0
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Structure of cephalosporin acylase in complex with glutarate
分子名称: GLUTARIC ACID, cephalosporin acylase alpha chain, cephalosporin acylase beta chain
著者Kim, Y, Hol, W.G.J.
登録日2001-09-01
公開日2002-09-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity
CHEM.BIOL., 8, 2001
1LTI
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BU of 1lti by Molmil
HEAT-LABILE ENTEROTOXIN (LT-I) COMPLEX WITH T-ANTIGEN
分子名称: HEAT LABILE ENTEROTOXIN TYPE I, beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
著者Van Den Akker, F, Hol, W.G.J.
登録日1996-05-09
公開日1996-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Tumor marker disaccharide D-Gal-beta 1, 3-GalNAc complexed to heat-labile enterotoxin from Escherichia coli.
Protein Sci., 5, 1996
1RQC
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Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design
分子名称: COBALT (II) ION, formylmethionine deformylase
著者Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G.
登録日2003-12-04
公開日2004-01-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An improved crystal form of Plasmodium falciparum peptide deformylase
Protein Sci., 13, 2004
1MU7
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Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Tungstate Complex
分子名称: GLYCEROL, TUNGSTATE(VI)ION, Tyrosyl-DNA Phosphodiesterase
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2003
2A0U
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Crystal structure of the eukaryotic initiation factor 2B from Leishmania major at 2.1 A resolution
分子名称: SULFATE ION, initiation factor 2B
著者Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-06-17
公開日2005-08-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the eukaryotic initiation factor 2B from Leishmania major at 2.1 A resolution
To be Published
2B51
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Structural Basis for UTP Specificity of RNA Editing TUTases from Trypanosoma Brucei
分子名称: MANGANESE (II) ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE
著者Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G.
登録日2005-09-27
公開日2005-11-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
2B30
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Initial Crystallographic Structural Analysis of a putative HAD/COF-like hydrolase from Plasmodium vivax
分子名称: CALCIUM ION, CHLORIDE ION, Pvivax hypothetical protein
著者Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-09-19
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Initial Crystallographic Structural Analysis of a putative HAD/COF-like hydrolase from Plasmodium vivax
To be Published
2B4V
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Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei
分子名称: POTASSIUM ION, RNA editing complex protein MP57
著者Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G.
登録日2005-09-26
公開日2005-11-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
2B56
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Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei
分子名称: MAGNESIUM ION, RNA editing complex protein MP57, URIDINE 5'-TRIPHOSPHATE, ...
著者Deng, J, Ernst, N.L, Turley, S, Stuart, K.D, Hol, W.G.
登録日2005-09-27
公開日2005-11-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei.
Embo J., 24, 2005
2B94
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Structural analysis of P knowlesi homolog of P falciparum PNP
分子名称: THIOSULFATE, purine nucleoside phosphorylase
著者Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-10-10
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural analysis of P knowlesi homolog of P falciparum PNP
To be Published
2BH1
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X-ray structure of the general secretion pathway complex of the N- terminal domain of EpsE and the cytosolic domain of EpsL of Vibrio cholerae
分子名称: CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN E,, GENERAL SECRETION PATHWAY PROTEIN L
著者Abendroth, J, Murphy, P.M, Mushtaq, A, Bagdasarian, M, Sandkvist, M, Hol, W.G.J.
登録日2005-01-06
公開日2005-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The X-Ray Structure of the Type II Secretion System Complex Formed by the N-Terminal Domain of Epse and the Cytoplasmic Domain of Epsl of Vibrio Cholerae
J.Mol.Biol., 348, 2005
2DTR
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STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR
分子名称: COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION
著者Qiu, X, Pohl, E, Hol, W.G.
登録日1996-07-26
公開日1997-08-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.
Biochemistry, 35, 1996
2F84
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Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from P.falciparum
分子名称: PHOSPHATE ION, orotidine monophosphate decarboxylase
著者Caruthers, J.M, Robein, M, Merritt, E.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-12-01
公開日2005-12-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from Plasmodium falciparum
To be Published
1HTI
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN TRIOSEPHOSPHATE ISOMERASE AT 2.8 ANGSTROMS RESOLUTION. TRIOSEPHOSPHATE ISOMERASE RELATED HUMAN GENETIC DISORDERS AND COMPARISON WITH THE TRYPANOSOMAL ENZYME
分子名称: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Mande, S.C, Hol, W.G.J.
登録日1994-10-12
公開日1995-01-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
Protein Sci., 3, 1994
1JDJ
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CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH 2-FLUORO-6-CHLOROPURINE
分子名称: 6-CHLORO-2-FLUOROPURINE, GLYCEROL-3-PHOSPHATE DEHYDROGENASE, PENTADECANE
著者Suresh, S, Wisedchaisri, G, Kennedy, K.J, Verlinde, C.L.M.J, Gelb, M.H, Hol, W.G.J.
登録日2001-06-14
公開日2002-06-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase.
Chem.Biol., 9, 2002
1JR0
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CHOLERA TOXIN B-PENTAMER WITH LIGAND BMSC-0011
分子名称: (3-NITRO-5-(2-MORPHOLIN-4-YL-ETHYLAMINOCARBONYL)PHENYL)-GALACTOPYRANOSIDE, cholera toxin B subunit
著者Merritt, E.A, Hol, W.G.J.
登録日2001-08-09
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes.
Chem.Biol., 9, 2002
1JY1
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CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1)
分子名称: TYROSYL-DNA PHOSPHODIESTERASE
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2001-09-10
公開日2002-02-20
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1.
Structure, 10, 2002
1JOA
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NADH PEROXIDASE WITH CYSTEINE-SULFENIC ACID
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH PEROXIDASE
著者Yeh, J.I, Claiborne, A.C, Hol, W.G.J.
登録日1996-07-02
公開日1997-01-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the native cysteine-sulfenic acid redox center of enterococcal NADH peroxidase refined at 2.8 A resolution.
Biochemistry, 35, 1996
1LLR
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CHOLERA TOXIN B-PENTAMER WITH LIGAND BMSC-0012
分子名称: 3-AMINO-4-{3-[2-(2-PROPOXY-ETHOXY)-ETHOXY]-PROPYLAMINO}-CYCLOBUT-3-ENE-1,2-DIONE, 5-aminocarbonyl-3-nitrophenyl alpha-D-galactopyranoside, CHOLERA TOXIN B SUBUNIT
著者Merritt, E.A, Hol, W.G.J.
登録日2002-04-30
公開日2002-08-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin.
J.Am.Chem.Soc., 124, 2002
1LEP
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THREE-DIMENSIONAL STRUCTURE OF THE IMMUNODOMINANT HEAT-SHOCK PROTEIN CHAPERONIN-10 OF MYCOBACTERIUM LEPRAE
分子名称: CHAPERONIN-10
著者Mande, S.C, Hol, W.G.J.
登録日1995-12-13
公開日1997-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the heat shock protein chaperonin-10 of Mycobacterium leprae.
Science, 271, 1996
1MD2
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CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013
分子名称: 3-ETHYLAMINO-4-METHYLAMINO-CYCLOBUTANE-1,2-DIONE, CHOLERA TOXIN B SUBUNIT, CYANIDE ION, ...
著者Zhang, Z, Merritt, E.A, Ahn, M, Roach, C, Hol, W.G.J, Fan, E.
登録日2002-08-06
公開日2002-12-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin.
J.Am.Chem.Soc., 124, 2002
1MU9
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Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Vanadate Complex
分子名称: GLYCEROL, Tyrosyl-DNA Phosphodiesterase, VANADATE ION
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002

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