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PDB: 336 results

3CHB
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BU of 3chb by Molmil
CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHOLERA TOXIN, UNKNOWN ATOM OR ION, ...
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1998-03-24
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.
J.Mol.Biol., 282, 1998
2A5F
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BU of 2a5f by Molmil
Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6
Descriptor: ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ...
Authors:O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J.
Deposit date:2005-06-30
Release date:2005-08-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
2SBT
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BU of 2sbt by Molmil
A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO
Descriptor: ACETONE, SUBTILISIN NOVO
Authors:Drenth, J, Hol, W.G.J, Jansonius, J.N, Koekoek, R.
Deposit date:1976-09-07
Release date:1976-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.
Cold Spring Harbor Symp.Quant.Biol., 36, 1972
3OSS
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The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system
Descriptor: CALCIUM ION, CHLORIDE ION, TYPE 2 SECRETION SYSTEM, ...
Authors:Korotkov, K.V, Pruneda, J, Hol, W.G.J.
Deposit date:2010-09-09
Release date:2011-08-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.
Plos Pathog., 7, 2011
4J76
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BU of 4j76 by Molmil
Crystal Structure of a parasite tRNA synthetase, ligand-free
Descriptor: GLYCEROL, Tryptophanyl-tRNA synthetase
Authors:Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:2013-02-12
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
4J75
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Crystal Structure of a parasite tRNA synthetase, product-bound
Descriptor: GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
Authors:Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:2013-02-12
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
3TEC
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BU of 3tec by Molmil
CALCIUM BINDING TO THERMITASE. CRYSTALLOGRAPHIC STUDIES OF THERMITASE AT 0, 5 AND 100 MM CALCIUM
Descriptor: CALCIUM ION, EGLIN C, THERMITASE
Authors:Gros, P, Kalk, K.H, Hol, W.G.J.
Deposit date:1990-10-26
Release date:1992-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium.
J.Biol.Chem., 266, 1991
3FU1
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BU of 3fu1 by Molmil
Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio cholerae
Descriptor: CALCIUM ION, General secretion pathway protein G, ZINC ION
Authors:Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
Deposit date:2009-01-13
Release date:2009-07-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
4IDL
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Low melting temperature Anti-Cholera Toxin Llama VHH domain
Descriptor: Single Domain Antibody VHH A9
Authors:Legler, P.M, Lam, A, Hol, W.G.J.
Deposit date:2012-12-12
Release date:2013-02-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure of a low-melting-temperature anti-cholera toxin: llama V(H)H domain.
Acta Crystallogr.,Sect.F, 69, 2013
2QV8
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Structure of the minor pseudopilin EpsH from the Type 2 Secretion System of Vibrio cholerae
Descriptor: General secretion pathway protein H
Authors:Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
Deposit date:2007-08-07
Release date:2008-02-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the minor pseudopilin EpsH from the Type 2 secretion system of Vibrio cholerae.
J.Mol.Biol., 377, 2008
3GN9
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Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio vulnificus
Descriptor: CALCIUM ION, D-MALATE, Type II secretory pathway, ...
Authors:Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
Deposit date:2009-03-16
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
2BP2
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BU of 2bp2 by Molmil
THE STRUCTURE OF BOVINE PANCREATIC PROPHOSPHOLIPASE A2 AT 3.0 ANGSTROMS RESOLUTION
Descriptor: PHOSPHOLIPASE A2
Authors:Dijkstra, B.W, Vannes, G.J.H, Kalk, K.H, Brandenburg, N.P, Hol, W.G.J, Drenth, J.
Deposit date:1981-06-05
Release date:1981-07-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of Bovine Pancreatic Prophospholipase A2 at 3.0 Angstroms Resolution
Acta Crystallogr.,Sect.B, 38, 1982
2CHB
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CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
Descriptor: CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1997-06-03
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
2TEC
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BU of 2tec by Molmil
MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT
Descriptor: CALCIUM ION, EGLIN C, THERMITASE
Authors:Gros, P, Betzel, C, Dauter, Z, Wilson, K.S, Hol, W.G.J.
Deposit date:1990-10-26
Release date:1992-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content.
J.Mol.Biol., 210, 1989
5V49
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BU of 5v49 by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
Descriptor: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
Authors:Barros-Alvarez, X, Hol, W.G.J.
Deposit date:2017-03-08
Release date:2017-07-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
3G20
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BU of 3g20 by Molmil
Crystal structure of the major pseudopilin from the type 2 secretion system of enterohaemorrhagic Escherichia coli
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
Deposit date:2009-01-30
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
2VMB
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The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
Descriptor: CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN F
Authors:Abendroth, J, Korotkov, K.V, Mitchell, D.D, Kreger, A, Hol, W.G.J.
Deposit date:2008-01-25
Release date:2009-02-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae.
J.Struct.Biol., 166, 2009
3TGH
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GAP50 the anchor in the inner membrane complex of Plasmodium
Descriptor: COBALT (II) ION, DIMETHYL SULFOXIDE, Glideosome-associated protein 50, ...
Authors:Bosch, J, Paige, M.H, Vaidya, A, Bergman, L, Hol, W.G.J.
Deposit date:2011-08-17
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum.
J.Struct.Biol., 178, 2012
2VMA
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BU of 2vma by Molmil
The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
Descriptor: CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN F, IODIDE ION
Authors:Abendroth, J, Korotkov, K.V, Mitchell, D.D, Kreger, A, Hol, W.G.J.
Deposit date:2008-01-25
Release date:2009-02-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae.
J.Struct.Biol., 166, 2009
4LK4
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Structure of Vibrio cholerae VesB protease
Descriptor: VESB protease
Authors:Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
Deposit date:2013-07-05
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional and Structural Characterization of Vibrio cholerae Extracellular Serine Protease B, VesB.
J.Biol.Chem., 289, 2014
4JTM
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Structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli
Descriptor: Type II secretion system protein D
Authors:Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
Deposit date:2013-03-23
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:A dodecameric ring-like structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli.
J.Struct.Biol., 18, 2013
2B4R
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Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 Angstrom Resolution reveals intriguing extra electron density in the active site
Descriptor: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-26
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site
Proteins, 62, 2006
3K81
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Structure of the central interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies
Descriptor: MP18 RNA editing complex protein, Single strand antibody VHH domain
Authors:Park, Y.-J, Hol, W.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
2B4T
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Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 Angstrom resolution reveals intriguing extra electron density in the active site
Descriptor: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase
Authors:Robien, M.A, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-09-26
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site
Proteins, 62, 2006
2RET
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The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus
Descriptor: CHLORIDE ION, EpsJ, Pseudopilin EpsI, ...
Authors:Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
Deposit date:2007-09-27
Release date:2008-02-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus.
J.Mol.Biol., 375, 2008

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