2Q8W
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2GHU
| Crystal structure of falcipain-2 from Plasmodium falciparum | Descriptor: | falcipain 2 | Authors: | Hogg, T, Nagarajan, K, Schmidt, C.L, Hilgenfeld, R. | Deposit date: | 2006-03-27 | Release date: | 2006-06-06 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural and Functional Characterization of Falcipain-2, a Hemoglobinase from the Malarial Parasite Plasmodium falciparum. J.Biol.Chem., 281, 2006
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1VJ7
| Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis. | Descriptor: | Bifunctional RELA/SPOT, GUANOSINE 5'-DIPHOSPHATE 2':3'-CYCLIC MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Hogg, T, Mechold, U, Malke, H, Cashel, M, Hilgenfeld, R. | Deposit date: | 2004-02-03 | Release date: | 2004-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response. Cell(Cambridge,Mass.), 117, 2004
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1EXM
| CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP. | Descriptor: | ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Hogg, T, Mesters, J.R, Hilgenfeld, R. | Deposit date: | 2000-05-03 | Release date: | 2000-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Insights into the GTPase Mechanism of EF-Tu from Structural Studies The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions, 28, 2000
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7OPQ
| Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CA1 in C188 | Descriptor: | 1-[(2~{S})-2-(4-methoxyphenyl)pyrrolidin-1-yl]propan-1-one, GLYCEROL, MAGNESIUM ION, ... | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | Deposit date: | 2021-06-01 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13, 2022
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7OPR
| Rab27a fusion with Slp2a-RBDa1 effector covalent adduct with CB1 in C123 | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | Deposit date: | 2021-06-01 | Release date: | 2022-04-06 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13, 2022
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7OPP
| Crystal structure of the Rab27a fusion with Slp2a-RBDa1 effector for SF4 pocket drug targeting | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Synaptotagmin-like protein 2,Ras-related protein Rab-27A | Authors: | Jamshidiha, M, Tersa, M, Lanyon-Hogg, T, Perez-Dorado, I, Sutherell, C.L, De Vita, E, Morgan, R.M.L, Tate, E.W, Cota, E. | Deposit date: | 2021-06-01 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. Rsc Med Chem, 13, 2022
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1JFX
| Crystal structure of the bacterial lysozyme from Streptomyces coelicolor at 1.65 A resolution | Descriptor: | 1,4-beta-N-Acetylmuramidase M1, CHLORIDE ION | Authors: | Rau, A, Hogg, T, Marquardt, R, Hilgenfeld, R. | Deposit date: | 2001-06-22 | Release date: | 2001-09-05 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A new lysozyme fold. Crystal structure of the muramidase from Streptomyces coelicolor at 1.65 A resolution. J.Biol.Chem., 276, 2001
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3I92
| Structure of the cytosolic domain of E. coli FeoB, GppCH2p-bound form | Descriptor: | Ferrous iron transport protein B, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Petermann, N, Hansen, G, Hogg, T, Hilgenfeld, R. | Deposit date: | 2009-07-10 | Release date: | 2009-07-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the intrinsic GTPase and GDI activities of FeoB, a prokaryotic transmembrane GTP/GDP-binding protein To be Published
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3I8X
| Structure of the cytosolic domain of E. coli FeoB, GDP-bound form | Descriptor: | Ferrous iron transport protein B, GUANOSINE-5'-DIPHOSPHATE | Authors: | Petermann, N, Hansen, G, Hogg, T, Hilgenfeld, R. | Deposit date: | 2009-07-10 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for the intrinsic GTPase and GDI activities of FeoB, a prokaryotic transmembrane GTP/GDP-binding protein To be Published
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3I8S
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