1VJ7
Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.
Summary for 1VJ7
Entry DOI | 10.2210/pdb1vj7/pdb |
Descriptor | Bifunctional RELA/SPOT, MANGANESE (II) ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | hd domain, alpha beta 2-layer sandwich, helix bundle, manganese, gdp, ppg2':3'p, (p)ppgpp, ppgpp, rela, spot, stringent response, stringent factor, stringent effector, magic spot, rsh, hydrolase, transferase |
Biological source | Streptococcus dysgalactiae subsp. equisimilis |
Total number of polymer chains | 2 |
Total formula weight | 92714.15 |
Authors | Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R. (deposition date: 2004-02-03, release date: 2004-05-04, Last modification date: 2024-02-14) |
Primary citation | Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R. Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response. Cell(Cambridge,Mass.), 117:57-68, 2004 Cited by PubMed: 15066282DOI: 10.1016/S0092-8674(04)00260-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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