1VJ7

Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.

Summary for 1VJ7

Entry DOI	10.2210/pdb1vj7/pdb
Descriptor	Bifunctional RELA/SPOT, MANGANESE (II) ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	hd domain, alpha beta 2-layer sandwich, helix bundle, manganese, gdp, ppg2':3'p, (p)ppgpp, ppgpp, rela, spot, stringent response, stringent factor, stringent effector, magic spot, rsh, hydrolase, transferase
Biological source	Streptococcus dysgalactiae subsp. equisimilis
Total number of polymer chains	2
Total formula weight	92714.15
Authors	Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R. (deposition date: 2004-02-03, release date: 2004-05-04, Last modification date: 2024-02-14)
Primary citation	Hogg, T.,Mechold, U.,Malke, H.,Cashel, M.,Hilgenfeld, R. Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response. Cell(Cambridge,Mass.), 117:57-68, 2004 Cited by PubMed: 15066282 DOI: 10.1016/S0092-8674(04)00260-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation