3BQK
 
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4E40
 | | The haptoglobin-hemoglobin receptor of Trypanosoma congolense | | Descriptor: | Putative uncharacterized protein | | Authors: | Higgins, M.K, Tkachenko, O, Brown, A, Reed, J, Carrington, M. | | Deposit date: | 2012-03-11 | | Release date: | 2013-01-16 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3BQI
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3BQL
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1T5E
 | | The structure of MexA | | Descriptor: | D-Glyceraldehyde, GLYCEROL, Multidrug resistance protein mexA | | Authors: | Higgins, M.K, Bokma, E, Koronakis, E, Hughes, C, Koronakis, V. | | Deposit date: | 2004-05-04 | | Release date: | 2004-05-18 | | Last modified: | 2020-07-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the periplasmic component of a bacterial drug efflux pump
Proc.Natl.Acad.Sci.USA, 101, 2004
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1TQQ
 | | Structure of TolC in complex with hexamminecobalt | | Descriptor: | COBALT HEXAMMINE(III), Outer membrane protein tolC | | Authors: | Higgins, M.K, Eswaran, J, Edwards, P.C, Schertler, G.F, Hughes, C, Koronakis, V. | | Deposit date: | 2004-06-18 | | Release date: | 2004-07-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug effllux protein TolC
J.Mol.Biol., 342, 2004
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6ZDX
 | | RIFIN variable region bound to LILRB1 ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... | | Authors: | Harrison, T.E, Higgins, M.K. | | Deposit date: | 2020-06-15 | | Release date: | 2020-07-22 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for RIFIN-mediated activation of LILRB1 in malaria.
Nature, 587, 2020
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4V3E
 | | The CIDRa domain from IT4var07 PfEMP1 bound to endothelial protein C receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | | Authors: | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | | Deposit date: | 2014-10-17 | | Release date: | 2014-12-17 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
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6ELU
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5HU6
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8CDE
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8CDD
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4E6Z
 | | Tic22 from Plasmodium falciparum | | Descriptor: | Apicoplast TIC22, putative, GLYCEROL | | Authors: | Glaser, S, Higgins, M.K. | | Deposit date: | 2012-03-16 | | Release date: | 2012-10-10 | | Last modified: | 2012-12-05 | | Method: | X-RAY DIFFRACTION (2.1501 Å) | | Cite: | Tic22 is an essential chaperone required for protein import into the apicoplast.
J.Biol.Chem., 287, 2012
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6H5N
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4X0J
 | | Trypanosoma brucei haptoglobin-haemoglobin receptor | | Descriptor: | Haptoglobin-hemoglobin receptor | | Authors: | Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K. | | Deposit date: | 2014-11-21 | | Release date: | 2014-12-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
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4X0L
 | | Human haptoglobin-haemoglobin complex | | Descriptor: | CACODYLATE ION, GLYCEROL, Haptoglobin, ... | | Authors: | Lane-Serff, H, MacGregor, P, Lowe, E.D, Carrington, M, Higgins, M.K. | | Deposit date: | 2014-11-21 | | Release date: | 2014-12-24 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor.
Elife, 3, 2014
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8OVB
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8PWW
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8PWU
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8PWV
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8PWX
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8Q5R
 | | HpARI bound to mouse IL-33 | | Descriptor: | 1,2-ETHANEDIOL, Alarmin release inhibitor, CHLORIDE ION, ... | | Authors: | Jamwal, A, Higgins, M.K. | | Deposit date: | 2023-08-09 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2.
Nat Commun, 15, 2024
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8RZ2
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8RZ0
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8RZ1
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