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PDB: 34 件

2BW3
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Three-dimensional structure of the Hermes DNA transposase
分子名称: TRANSPOSASE
著者Hickman, A.B, Perez, Z.N, Zhou, L, Musingarimi, P, Ghirlando, R, Hinshaw, J.E, Craig, N.L, Dyda, F.
登録日2005-07-11
公開日2005-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Architecture of a Eukaryotic DNA Transposase
Nat.Struct.Mol.Biol., 12, 2005
1F1Z
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TNSA, a catalytic component of the TN7 transposition system
分子名称: CHLORIDE ION, MAGNESIUM ION, TNSA ENDONUCLEASE
著者Hickman, A.B, Li, Y, Mathew, S.V, May, E.W, Craig, N.L, Dyda, F.
登録日2000-05-21
公開日2000-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unexpected structural diversity in DNA recombination: the restriction endonuclease connection.
Mol.Cell, 5, 2000
1CJW
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SEROTONIN N-ACETYLTRANSFERASE COMPLEXED WITH A BISUBSTRATE ANALOG
分子名称: COA-S-ACETYL TRYPTAMINE, PROTEIN (SEROTONIN N-ACETYLTRANSFERASE)
著者Hickman, A.B, Namboodiri, M.A.A, Klein, D.C, Dyda, F.
登録日1999-04-19
公開日1999-05-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structural basis of ordered substrate binding by serotonin N-acetyltransferase: enzyme complex at 1.8 A resolution with a bisubstrate analog.
Cell(Cambridge,Mass.), 97, 1999
1RZ9
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Crystal Structure of AAV Rep complexed with the Rep-binding sequence
分子名称: 26-MER, Rep protein
著者Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F.
登録日2003-12-24
公開日2004-02-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
1M55
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Catalytic domain of the Adeno Associated Virus type 5 Rep protein
分子名称: CHLORIDE ION, Rep protein, ZINC ION
著者Hickman, A.B, Ronning, D.R, Kotin, R.M, Dyda, F.
登録日2002-07-08
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep.
Mol.Cell, 10, 2002
2XM3
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Deinococcus radiodurans ISDra2 Transposase Left end DNA complex
分子名称: 5'-D(*TP*TP*AP*GP*T)-3', ACETATE ION, DRA2 TRANSPOSASE BINDING ELEMENT, ...
著者Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
登録日2010-07-22
公開日2010-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XQC
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DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN
分子名称: 5'-D(TP*TP*GP*AP*TP*GP)-3', DRA2 TRANSPOSASE LEFT END RECOGNITION SEQUENCE, TRANSPOSASE, ...
著者Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
登録日2010-09-01
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XMA
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DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE RIGHT END DNA COMPLEX
分子名称: DRA2 TRANSPOSASE RIGHT END RECOGNITION SITE, MAGNESIUM ION, TRANSPOSASE
著者Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
登録日2010-07-26
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XO6
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DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE Y132F MUTANT COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE
分子名称: 5'-D(*TP*TP*GP*AP*TP*G)-3', ACETATE ION, CADMIUM ION, ...
著者Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
登録日2010-08-09
公開日2010-10-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
1AIH
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CATALYTIC DOMAIN OF BACTERIOPHAGE HP1 INTEGRASE
分子名称: HP1 INTEGRASE, MAGNESIUM ION, SULFATE ION
著者Hickman, A.B, Waninger, S, Scocca, J.J, Dyda, F.
登録日1997-04-17
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution.
Cell(Cambridge,Mass.), 89, 1997
1B6B
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MELATONIN BIOSYNTHESIS: THE STRUCTURE OF SEROTONIN N-ACETYLTRANSFERASE AT 2.5 A RESOLUTION SUGGESTS A CATALYTIC MECHANISM
分子名称: PROTEIN (ARYLALKYLAMINE N-ACETYLTRANSFERASE)
著者Hickman, A.B, Klein, D.C, Dyda, F.
登録日1999-01-13
公開日2000-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Melatonin biosynthesis: the structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism.
Mol.Cell, 3, 1999
4D1Q
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Hermes transposase bound to its terminal inverted repeat
分子名称: SODIUM ION, TERMINAL INVERTED REPEAT, TRANSPOSASE
著者Hickman, A.B, Ewis, H, Li, X, Knapp, J, Laver, T, Doss, A.L, Tolun, G, Steven, A, Grishaev, A, Bax, A, Atkinson, P, Craig, N.L, Dyda, F.
登録日2014-05-04
公開日2014-07-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis of Hat Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca Domestica.
Cell(Cambridge,Mass.), 158, 2014
7TH0
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Escherichia coli RpnA-S
分子名称: Recombination-promoting nuclease RpnA
著者Zhong, A, Hickman, A.B, Storz, G, Dyda, F.
登録日2022-01-10
公開日2023-03-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
5LME
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Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase
分子名称: ZINC ION, piggyBac transposase
著者Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E.
登録日2016-07-30
公開日2017-12-20
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase.
Nucleic Acids Res., 46, 2018
1T0F
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Crystal Structure of the TnsA/TnsC(504-555) complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MALONIC ACID, ...
著者Ronning, D.R, Li, Y, Perez, Z.N, Ross, P.D, Hickman, A.B, Craig, N.L, Dyda, F.
登録日2004-04-08
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Embo J., 23, 2004
4ER8
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Structure of the REP associates tyrosine transposase bound to a REP hairpin
分子名称: DNA (32-MER), NICKEL (II) ION, TnpArep for protein
著者Messing, S.A.J, Ton-Hoang, B, Hickman, A.B, Ghirlando, R, Chandler, M, Dyda, F.
登録日2012-04-19
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease.
Nucleic Acids Res., 40, 2012
1ITG
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES
分子名称: CACODYLATE ION, HIV-1 INTEGRASE
著者Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R.
登録日1994-11-21
公開日1995-05-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
1UUT
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The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat
分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ...
著者Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M.
登録日2004-01-10
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004
1BIS
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HIV-1 INTEGRASE CORE DOMAIN
分子名称: HIV-1 INTEGRASE
著者Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R.
登録日1998-06-19
公開日1998-08-19
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIZ
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HIV-1 INTEGRASE CORE DOMAIN
分子名称: CACODYLATE ION, HIV-1 INTEGRASE
著者Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R.
登録日1998-06-21
公開日1998-08-19
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIU
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HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++
分子名称: HIV-1 INTEGRASE, MAGNESIUM ION
著者Goldgur, Y, Dyda, F, Hickman, A.B, Jenkins, T.M, Craigie, R, Davies, D.R.
登録日1998-06-19
公開日1998-08-19
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
6X67
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Cryo-EM structure of piggyBac transposase strand transfer complex (STC)
分子名称: CALCIUM ION, DNA (37-MER), DNA (47-MER), ...
著者Chen, Q, Hickman, A.B, Dyda, F.
登録日2020-05-27
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
6X68
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Cryo-EM structure of piggyBac transposase synaptic complex with hairpin DNA (SNHP)
分子名称: CALCIUM ION, Transposase, ZINC ION, ...
著者Chen, Q, Hickman, A.B, Dyda, F.
登録日2020-05-27
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
6OPM
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Casposase bound to integration product
分子名称: CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ...
著者Dyda, F, Hickman, A.B, Kailasan, S.
登録日2019-04-25
公開日2020-02-12
最終更新日2020-08-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Elife, 9, 2020
6DWZ
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Hermes transposase deletion dimer complex with (C/G) DNA
分子名称: DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ...
著者Dyda, F, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018

 

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