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PDB: 264 results

5ANZ
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BU of 5anz by Molmil
Crystal Structure of SltB3 from Pseudomonas aeruginosa.
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, SOLUBLE LYTIC TRANSGLYCOSYLASE B3
Authors:Dominguez-Gil, T, Hermoso, J.A.
Deposit date:2015-09-09
Release date:2016-07-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.614 Å)
Cite:Turnover of Bacterial Cell Wall by Sltb3, a Multidomain Lytic Transglycosylase of Pseudomonas Aeruginosa.
Acs Chem.Biol., 11, 2016
7O4C
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BU of 7o4c by Molmil
Crystal structure of PASTA domains of the Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus
Descriptor: CHLORIDE ION, Penicillin-binding protein 1
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-04-05
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery.
Comput Struct Biotechnol J, 19, 2021
8BRE
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BU of 8bre by Molmil
1,6-anhydro-n-actetylmuramic acid kinase (AnmK)
Descriptor: Anhydro-N-acetylmuramic acid kinase, CHLORIDE ION
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2022-11-23
Release date:2023-09-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa.
J.Biol.Chem., 299, 2023
8CPB
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BU of 8cpb by Molmil
1,6-anhydro-n-actetylmuramic acid kinase (AnmK) in complex with AMPPNP, and AnhMurNAc at 1.7 Angstroms resolution.
Descriptor: 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, Anhydro-N-acetylmuramic acid kinase, GLYCEROL, ...
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2023-03-02
Release date:2023-09-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa.
J.Biol.Chem., 299, 2023
8CP9
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BU of 8cp9 by Molmil
1,6-anhydro-n-actetylmuramic acid kinase (AnmK)in complex with non-hydrolyzable AMPPNP.
Descriptor: Anhydro-N-acetylmuramic acid kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2023-03-02
Release date:2023-09-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa.
J.Biol.Chem., 299, 2023
8C0U
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BU of 8c0u by Molmil
1,6-anhydro-n-actetylmuramic acid kinase (AnmK) in complex with their natural substrates and products
Descriptor: (2~{R})-2-[(2~{S},3~{R},4~{R},5~{S},6~{R})-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2022-12-19
Release date:2023-09-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.112 Å)
Cite:Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa.
J.Biol.Chem., 299, 2023
7O4A
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BU of 7o4a by Molmil
Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with piperacillin
Descriptor: Hydrolyzed piperacillin, Penicillin-binding protein 1
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-04-05
Release date:2021-11-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.028 Å)
Cite:Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery.
Comput Struct Biotechnol J, 19, 2021
7O4B
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BU of 7o4b by Molmil
Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with penicillin G
Descriptor: CITRIC ACID, OPEN FORM - PENICILLIN G, Penicillin-binding protein 1, ...
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-04-05
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.593 Å)
Cite:Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery.
Comput Struct Biotechnol J, 19, 2021
8R7S
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BU of 8r7s by Molmil
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with NIM811 (N-methyl-4-isoleucine cyclosporin)
Descriptor: CYCLOSPORIN A, 8 mutation, Peptidyl-prolyl cis-trans isomerase
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2023-11-27
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Evaluating the potential of non-immunosuppressive cyclosporin analogs for targeting Toxoplasma gondii cyclophilin: Insights from structural studies.
Protein Sci., 33, 2024
8R7U
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BU of 8r7u by Molmil
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with dihydro Cyclosporin A
Descriptor: Dihydrocyclosporin A, Peptidyl-prolyl cis-trans isomerase
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2023-11-27
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Evaluating the potential of non-immunosuppressive cyclosporin analogs for targeting Toxoplasma gondii cyclophilin: Insights from structural studies.
Protein Sci., 33, 2024
8R7T
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BU of 8r7t by Molmil
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Alisporivir (nonimmunosuppressive analogue of Cyclosporin)
Descriptor: Alisporivir, Peptidyl-prolyl cis-trans isomerase
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2023-11-27
Release date:2024-10-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Evaluating the potential of non-immunosuppressive cyclosporin analogs for targeting Toxoplasma gondii cyclophilin: Insights from structural studies.
Protein Sci., 33, 2024
7PL3
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BU of 7pl3 by Molmil
Crystal structure of catalytic domain in closed conformation of LytB from Streptococcus pneumoniae
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ...
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-08-28
Release date:2022-09-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis of the final step of cell division in Streptococcus pneumoniae.
Cell Rep, 42, 2023
8C0P
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BU of 8c0p by Molmil
Crystal structure of S. aureus BlaR1 sensor domain in complex with a boronate inhibitor
Descriptor: Regulatory protein BlaR1, [1-[[2,4-bis(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]sulfanylmethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron
Authors:Miguel-Ruano, V, Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2022-12-19
Release date:2024-07-10
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus.
Nat.Chem.Biol., 2024
8C0S
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BU of 8c0s by Molmil
Crystal structure of S. aureus BlaR1 sensor domain in complex with an imidazole inhibitor
Descriptor: 3-[[2,4-bis(trifluoromethyl)phenyl]methyl]-5-(hydroxymethyl)-1~{H}-imidazole-2-thione, Regulatory protein BlaR1
Authors:Miguel-Ruano, V, Hermoso, J.A.
Deposit date:2022-12-19
Release date:2024-07-10
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus.
Nat.Chem.Biol., 2024
8CF3
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BU of 8cf3 by Molmil
Crystal structure of S. aureus BlaR1 sensor domain in complex with cefepime
Descriptor: Cefepime (open), Regulatory protein BlaR1
Authors:Miguel-Ruano, V, Hermoso, J.A.
Deposit date:2023-02-02
Release date:2024-09-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus.
Nat.Chem.Biol., 2024
8B58
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BU of 8b58 by Molmil
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Cyclosporin A
Descriptor: Cyclosporin A, Peptidyl-prolyl cis-trans isomerase
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2022-09-22
Release date:2023-02-01
Last modified:2023-02-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii .
Acs Infect Dis., 9, 2023
7OK9
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BU of 7ok9 by Molmil
Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with pentaglycine
Descriptor: CADMIUM ION, CHLORIDE ION, Penicillin-binding protein 1, ...
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-05-17
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery.
Comput Struct Biotechnol J, 19, 2021
1BGG
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BU of 1bgg by Molmil
GLUCOSIDASE A FROM BACILLUS POLYMYXA COMPLEXED WITH GLUCONATE
Descriptor: BETA-GLUCOSIDASE A, D-gluconic acid
Authors:Sanz-Aparicio, J, Hermoso, J, Martinez-Ripoll, M, Polaina, J.
Deposit date:1997-05-12
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of beta-glucosidase A from Bacillus polymyxa: insights into the catalytic activity in family 1 glycosyl hydrolases.
J.Mol.Biol., 275, 1998
2BGI
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BU of 2bgi by Molmil
X-Ray Structure of the Ferredoxin-NADP(H) Reductase from Rhodobacter capsulatus complexed with three molecules of the detergent n-heptyl- beta-D-thioglucoside at 1.7 Angstroms
Descriptor: CARBON DIOXIDE, FERREDOXIN-NADP(H) REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Perez-Dorado, J.I, Hermoso, J.A, Nogues, I, Frago, S, Bittel, C, Mayhew, S.G, Gomez-Moreno, C, Medina, M, Cortez, N, Carrillo, N.
Deposit date:2004-12-23
Release date:2005-09-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Ferredoxin-Nadp(H) Reductase from Rhodobacter Capsulatus: Molecular Structure and Catalytic Mechanism
Biochemistry, 44, 2005
2BGJ
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BU of 2bgj by Molmil
X-Ray Structure of the Ferredoxin-NADP(H) Reductase from Rhodobacter capsulatus at 2.1 Angstroms
Descriptor: FERREDOXIN-NADP(H) REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Perez-Dorado, J.I, Hermoso, J.A, Nogues, I, Frago, S, Bittel, C, Mayhew, S.G, Gomez-Moreno, C, Medina, M, Cortez, N, Carrillo, N.
Deposit date:2004-12-23
Release date:2005-09-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The ferredoxin-NADP(H) reductase from Rhodobacter capsulatus: molecular structure and catalytic mechanism.
Biochemistry, 44, 2005
3ZG0
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BU of 3zg0 by Molmil
Crystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and muramic acid at allosteric site obtained by cocrystallization
Descriptor: CADMIUM ION, CHLORIDE ION, Ceftaroline, ...
Authors:Otero, L.H, Rojas-Altuve, A, Hermoso, J.A.
Deposit date:2012-12-13
Release date:2013-10-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:How Allosteric Control of Staphylococcus Aureus Penicillin Binding Protein 2A Enables Methicillin Resistance and Physiological Function
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZFZ
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BU of 3zfz by Molmil
Crystal structure of ceftaroline acyl-PBP2a from MRSA with non- covalently bound ceftaroline and muramic acid at allosteric site obtained by soaking
Descriptor: CADMIUM ION, CHLORIDE ION, Ceftaroline, ...
Authors:Otero, L.H, Rojas-Altuve, A, Hermoso, J.A.
Deposit date:2012-12-13
Release date:2013-10-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:How Allosteric Control of Staphylococcus Aureus Penicillin Binding Protein 2A Enables Methicillin Resistance and Physiological Function
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZH3
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BU of 3zh3 by Molmil
crystal structure of S. pneumoniae D39 native MurA1
Descriptor: UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE
Authors:Gutierrez-Fernandez, J, Hermoso, J.A.
Deposit date:2012-12-20
Release date:2013-04-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Heteroresistance to Fosfomycin is Predominant in Streptococcus Pneumoniae and Depends on Mura1 Gene.
Antimicrob.Agents Chemother., 57, 2013
3ZG5
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BU of 3zg5 by Molmil
Crystal structure of PBP2a from MRSA in complex with peptidoglycan analogue at allosteric
Descriptor: CADMIUM ION, CHLORIDE ION, PEPTIDOGLYCAN ANALOGUE, ...
Authors:Otero, L.H, Rojas-Altuve, A, Hermoso, J.A.
Deposit date:2012-12-14
Release date:2013-10-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:How Allosteric Control of Staphylococcus Aureus Penicillin Binding Protein 2A Enables Methicillin Resistance and Physiological Function
Proc.Natl.Acad.Sci.USA, 110, 2013
7PL2
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BU of 7pl2 by Molmil
Crystal structure of choline-binding module of LytB from Streptococcus pneumoniae
Descriptor: CHOLINE ION, Putative endo-beta-N-acetylglucosaminidase
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-08-28
Release date:2022-09-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Molecular basis of the final step of cell division in Streptococcus pneumoniae.
Cell Rep, 42, 2023

226707

數據於2024-10-30公開中

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