8B58
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Cyclosporin A
Summary for 8B58
| Entry DOI | 10.2210/pdb8b58/pdb |
| Related PRD ID | PRD_000142 |
| Descriptor | Peptidyl-prolyl cis-trans isomerase, Cyclosporin A (3 entities in total) |
| Functional Keywords | cyclophilin, isomerase-immunosuppressant complex, isomerase |
| Biological source | Toxoplasma gondii More |
| Total number of polymer chains | 4 |
| Total formula weight | 48437.53 |
| Authors | Jimenez-Faraco, E.,Hermoso, J.A. (deposition date: 2022-09-22, release date: 2023-02-01, Last modification date: 2023-02-22) |
| Primary citation | Favretto, F.,Jimenez-Faraco, E.,Conter, C.,Dominici, P.,Hermoso, J.A.,Astegno, A. Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii . Acs Infect Dis., 9:365-377, 2023 Cited by PubMed: 36653744DOI: 10.1021/acsinfecdis.2c00566 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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