2FZK
 
 | | The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.50 Resolution | | Descriptor: | 3,5-BIS[(PHOSPHONOACETYL)AMINO]BENZOIC ACID, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ... | | Authors: | Heng, S, Stieglitz, K.A, Eldo, J, Xia, J, Cardia, J.P, Kantrowitz, E.R. | | Deposit date: | 2006-02-09 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45, 2006
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2FZG
 | | The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.25 Resolution | | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Heng, S, Stieglitz, K.A, Eldo, J, Xia, J, Cardia, J.P, Kantrowitz, E.R. | | Deposit date: | 2006-02-09 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45, 2006
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2FZC
 | | The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.10 Resolution | | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Heng, S, Stieglitz, K.A, Eldo, J, Xia, J, Cardia, J.P, Kantrowitz, E.R. | | Deposit date: | 2006-02-09 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45, 2006
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9IJE
 | | Epinephrine-activated human beta3 adrenergic receptor | | Descriptor: | Beta-3 adrenergic receptor, Camelid antibody VHH fragment, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | | Deposit date: | 2024-06-22 | | Release date: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.34 Å) | | Cite: | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker.
Chempluschem, 2024
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9IJD
 | | Carazolol-activated human beta3 adrenergic receptor | | Descriptor: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, Beta-3 adrenergic receptor, Camelid antibody VHH fragment, ... | | Authors: | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | | Deposit date: | 2024-06-22 | | Release date: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker.
Chempluschem, 2024
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6PLL
 | | Crystal structure of the ZIG-8 IG1 homodimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Zwei Ig domain protein zig-8 | | Authors: | Cheng, S, Ozkan, E. | | Deposit date: | 2019-07-01 | | Release date: | 2020-07-08 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.693 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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2KGP
 | | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone) | | Descriptor: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, RNA (25-MER) | | Authors: | Zheng, S, Chen, Y, Donahue, C.P, Wolfe, M.S, Varani, G. | | Deposit date: | 2009-03-13 | | Release date: | 2009-06-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone).
Chem.Biol., 16, 2009
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2KHP
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2L2S
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2KO7
 | | Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with Cycloheximide-N-ethylethanoate | | Descriptor: | Peptidyl-prolyl cis-trans isomerase, ethyl (4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}-2,6-dioxopiperidin-1-yl)acetate | | Authors: | Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2009-09-11 | | Release date: | 2009-09-29 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
Biochem.J., 437, 2011
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8CY8
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6NRR
 | | Crystal structure of Dpr11 IG1 bound to DIP-gamma IG+IG2 | | Descriptor: | Defective proboscis extension response 11, isoform B, Dpr-interacting protein gamma, ... | | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
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6NRW
 | | Crystal structure of Dpr1 IG1 bound to DIP-eta IG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
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6ON9
 | | Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, tetragonal form | | Descriptor: | NeuRonal IgCAM-5, SODIUM ION, SULFATE ION, ... | | Authors: | Cheng, S, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-04-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.995 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6ONB
 | | Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, monoclinic form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NeuRonal IgCAM-5, ... | | Authors: | Cheng, S, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-04-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.696 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6NRX
 | | Crystal structure of DIP-eta IG1 homodimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein eta, isoform B, ... | | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
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8TK9
 | | ZIG-4-INS-6 complex, tetragonal form | | Descriptor: | GLYCEROL, Probable insulin-like peptide beta-type 5, SULFATE ION, ... | | Authors: | Cheng, S, Baltrusaitis, E, Aziz, Z, Nawrocka, W.I, Ozkan, E. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
To Be Published
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6NRQ
 | | Crystal structure of Dpr10 IG1 bound to DIP-alpha IG1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Defective proboscis extension response 10, isoform A, ... | | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
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6NS1
 | | Crystal structure of DIP-gamma IG1+IG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein gamma | | Authors: | Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-01-24 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
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6ON6
 | | Crystal Structure of the RIG-5 IG1 homodimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NeuRonal IgCAM-5 | | Authors: | Cheng, S, Kurleto, J.D, Ozkan, E. | | Deposit date: | 2019-04-20 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.423 Å) | | Cite: | Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8K33
 | | SOD1 and Nanobody1 complex | | Descriptor: | NB1, Superoxide dismutase [Cu-Zn], ZINC ION | | Authors: | Cheng, S. | | Deposit date: | 2023-07-14 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | SOD1 and Nanobody1 complex
To Be Published
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8TKU
 | | ZIG-4-INS-6 complex, primitive monoclinic form | | Descriptor: | Probable insulin-like peptide beta-type 5, Zwei Ig domain protein zig-4 | | Authors: | Cheng, S, Baltrusaitis, E, Aziz, Z, Nawrocka, W.I, Ozkan, E. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
To Be Published
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8TKT
 | | ZIG-4-INS-6 complex, C-centered monoclinic form | | Descriptor: | Probable insulin-like peptide beta-type 5, Zwei Ig domain protein zig-4 | | Authors: | Cheng, S, Baltrusaitis, E, Aziz, Z, Nawrocka, W.I, Ozkan, E. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
To Be Published
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8K3A
 | | SOD1 and Nanobody2 complex | | Descriptor: | NB2, Superoxide dismutase [Cu-Zn], ZINC ION | | Authors: | Cheng, S. | | Deposit date: | 2023-07-14 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | SOD1 and Nanobody1 complex
To Be Published
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4QMF
 | | Structure of the Krr1 and Faf1 complex from Saccharomyces cerevisiae | | Descriptor: | KRR1 small subunit processome component, Protein FAF1 | | Authors: | Zheng, S, Ye, K. | | Deposit date: | 2014-06-16 | | Release date: | 2014-07-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | Interaction between ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast
J.Biol.Chem., 289, 2014
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