6R84
 
 | | Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | | Deposit date: | 2019-03-31 | | Release date: | 2019-06-26 | | Last modified: | 2019-07-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
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1CTP
 | | STRUCTURE OF THE MAMMALIAN CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND AN INHIBITOR PEPTIDE DISPLAYS AN OPEN CONFORMATION | | Descriptor: | MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE, cAMP-dependent protein kinase inhibitor, ... | | Authors: | Karlsson, R, Zheng, J, Xuong, N.H, Taylor, S.S, Sowadski, J.M. | | Deposit date: | 1993-04-08 | | Release date: | 1994-01-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of the mammalian catalytic subunit of cAMP-dependent protein kinase and an inhibitor peptide displays an open conformation.
Acta Crystallogr.,Sect.D, 49, 1993
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5AYW
 | | Structure of a membrane complex | | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | Authors: | Huang, Y, Han, L, Zheng, J. | | Deposit date: | 2015-09-14 | | Release date: | 2016-02-24 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.555 Å) | | Cite: | Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins
Nat.Struct.Mol.Biol., 23, 2016
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1BJH
 | | HAIRPIN LOOPS CONSISTING OF SINGLE ADENINE RESIDUES CLOSED BY SHEARED A(DOT)A AND G(DOT)G PAIRS FORMED BY THE DNA TRIPLETS AAA AND GAG: SOLUTION STRUCTURE OF THE D(GTACAAAGTAC) HAIRPIN, NMR, 16 STRUCTURES | | Descriptor: | DNA (5'-D(*GP*TP*AP*CP*AP*AP*AP*GP*TP*AP*C)-3') | | Authors: | Chou, S.-H, Zhu, L, Gao, Z, Cheng, J.-W, Reid, B.R. | | Deposit date: | 1997-07-25 | | Release date: | 1997-12-03 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Hairpin loops consisting of single adenine residues closed by sheared A.A and G.G pairs formed by the DNA triplets AAA and GAG: solution structure of the d(GTACAAAGTAC) hairpin.
J.Mol.Biol., 264, 1996
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1D69
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4DSI
 | | Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, Se-dGTP and Calcium | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, CALCIUM ION, DNA, ... | | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | | Deposit date: | 2012-02-19 | | Release date: | 2013-03-27 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase
To be Published
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4BCD
 | | PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN WITH A NON-COVALENTLY BOUND P2-substituted N-acyl-prolylpyrrolidine inhibitor | | Descriptor: | 1-[(2S,4S)-4-[4-(4-fluorophenyl)-1,2,3-triazol-1-yl]-2-pyrrolidin-1-ylcarbonyl-pyrrolidin-1-yl]-4-phenyl-butan-1-one, GLYCEROL, PROLYL ENDOPEPTIDASE, ... | | Authors: | VanDerVeken, P, Fulop, V, Rea, D, Gerard, M, VanElzen, R, Joossens, J, Cheng, J.D, Baekelandt, V, DeMeester, I, Lambeir, A.M, Augustyns, K. | | Deposit date: | 2012-10-01 | | Release date: | 2013-03-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | P2-Substituted N-Acylprolylpyrrolidine Inhibitors of Prolyl Oligopeptidase: Biochemical Evaluation, Binding Mode Determination, and Assessment in a Cellular Model of Synucleinopathy.
J.Med.Chem., 55, 2012
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4BCB
 | | PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN WITH A COVALENTLY BOUND P2- substituted N-acyl-prolylpyrrolidine inhibitor | | Descriptor: | (5R,6R,8S)-8-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-5-CYCLOHEXYL-6-HYDROXY-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE, GLYCEROL, PROLYL ENDOPEPTIDASE, ... | | Authors: | VanDerVeken, P, Fulop, V, Rea, D, Gerard, M, VanElzen, R, Joossens, J, Cheng, J.D, Baekelandt, V, DeMeester, I, Lambeir, A.M, Augustyns, K. | | Deposit date: | 2012-10-01 | | Release date: | 2013-03-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | P2-Substituted N-Acylprolylpyrrolidine Inhibitors of Prolyl Oligopeptidase: Biochemical Evaluation, Binding Mode Determination, and Assessment in a Cellular Model of Synucleinopathy.
J.Med.Chem., 55, 2012
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8PV2
 | | Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1 | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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175D
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8PV3
 | | Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV7
 | | Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.12 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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4DWI
 | | Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with self complementary DNA, Se-dGTP and Calcium | | Descriptor: | 9-METHYLGUANINE, CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), ... | | Authors: | Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. | | Deposit date: | 2012-02-24 | | Release date: | 2013-03-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase
To be Published
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8PV1
 | | Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV5
 | | Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV4
 | | Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PV6
 | | Chaetomium thermophilum pre-60S State 3 - post-5S rotation with Rix1 complex with Foot - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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6G53
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State E | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-28 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G18
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State C | | Descriptor: | 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-20 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G4S
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | | Descriptor: | 40S ribosomal protein S11, 40S ribosomal protein S13, 40S ribosomal protein S14, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-28 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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6G5H
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | Deposit date: | 2018-03-29 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
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2CPK
 | | CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CYCLIC ADENOSINE MONOPHOSPHATE-DEPENDENT PROTEIN KINASE | | Descriptor: | PEPTIDE INHIBITOR 20-MER, cAMP-DEPENDENT PROTEIN KINASE, CATALYTIC SUBUNIT | | Authors: | Knighton, D.R, Zheng, J, Teneyck, L.F, Ashford, V.A, Xuong, N.-H, Taylor, S.S, Sowadski, J.M. | | Deposit date: | 1992-10-21 | | Release date: | 1993-01-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
Science, 253, 1991
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8PVK
 | | Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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8PVL
 | | Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure | | Descriptor: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | Deposit date: | 2023-07-17 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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5TDJ
 | | RNA decamer duplex with four 2'-5'-linkages | | Descriptor: | RNA (5'-R(*CP*CP*GP*GP*CP*GP*CP*CP*GP*G)-3'), STRONTIUM ION | | Authors: | Luo, Z, Sheng, J. | | Deposit date: | 2016-09-19 | | Release date: | 2017-01-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural insights into RNA duplexes with multiple 2 -5 -linkages.
Nucleic Acids Res., 45, 2017
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