9DNA
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2D25
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![BU of 2d25 by Molmil](/molmil-images/mine/2d25) | C-C-A-G-G-C-M5C-T-G-G; HELICAL FINE STRUCTURE, HYDRATION, AND COMPARISON WITH C-C-A-G-G-C-C-T-G-G | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*GP*CP*(5CM)P*TP*GP*G)-3'), MAGNESIUM ION | Authors: | Heinemann, U, Hahn, M. | Deposit date: | 1991-04-23 | Release date: | 1991-04-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | C-C-A-G-G-C-m5C-T-G-G. Helical fine structure, hydration, and comparison with C-C-A-G-G-C-C-T-G-G. J.Biol.Chem., 267, 1992
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6HD0
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6HD3
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![BU of 6hd3 by Molmil](/molmil-images/mine/6hd3) | Common mode of remodeling AAA ATPases p97/CDC48 by their disassembly cofactors ASPL/PUX1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 48 homolog A, PHOSPHATE ION | Authors: | Heinemann, U, Roske, Y, Banchenko, S, Arumughan, A, Petrovic, S. | Deposit date: | 2018-08-17 | Release date: | 2019-08-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1. Structure, 27, 2019
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3ANA
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1D26
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1CGC
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1BD1
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![BU of 1bd1 by Molmil](/molmil-images/mine/1bd1) | CRYSTALLOGRAPHIC STUDY OF ONE TURN OF G/C-RICH B-DNA | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*GP*CP*CP*TP*GP*G)-3'), TRIETHYLAMMONIUM ION | Authors: | Heinemann, U. | Deposit date: | 1989-08-16 | Release date: | 1990-01-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic study of one turn of G/C-rich B-DNA. J.Mol.Biol., 210, 1989
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2RNT
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![BU of 2rnt by Molmil](/molmil-images/mine/2rnt) | THREE-DIMENSIONAL STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE AT 1.8 ANGSTROMS RESOLUTION | Descriptor: | CALCIUM ION, GUANYLYL-2',5'-PHOSPHOGUANOSINE, RIBONUCLEASE T1 | Authors: | Saenger, W, Koepke, J, Maslowska, M, Heinemann, U. | Deposit date: | 1988-07-06 | Release date: | 1989-10-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of ribonuclease T1 complexed with guanylyl-2',5'-guanosine at 1.8 A resolution. J.Mol.Biol., 206, 1989
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1MAC
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![BU of 1mac by Molmil](/molmil-images/mine/1mac) | CRYSTAL STRUCTURE AND SITE-DIRECTED MUTAGENESIS OF BACILLUS MACERANS ENDO-1,3-1,4-BETA-GLUCANASE | Descriptor: | 1,3-1,4-BETA-D-GLUCAN 4-GLUCANOHYDROLASE, CALCIUM ION | Authors: | Hahn, M, Heinemann, U. | Deposit date: | 1994-12-22 | Release date: | 1995-02-27 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure and site-directed mutagenesis of Bacillus macerans endo-1,3-1,4-beta-glucanase. J.Biol.Chem., 270, 1995
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4URR
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![BU of 4urr by Molmil](/molmil-images/mine/4urr) | Tailspike protein of Sf6 bacteriophage bound to Shigella flexneri O- antigen octasaccharide fragment | Descriptor: | 1,2-ETHANEDIOL, BIFUNCTIONAL TAIL PROTEIN, MANGANESE (II) ION, ... | Authors: | Gohlke, U, Heinemann, U, Seckler, R, Barbirz, S. | Deposit date: | 2014-07-01 | Release date: | 2015-07-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein-Polysaccharide Interactions. J.Am.Chem.Soc., 138, 2016
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9RNT
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4UUY
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![BU of 4uuy by Molmil](/molmil-images/mine/4uuy) | Structural Identification of the Vps18 beta-propeller reveals a critical role in the HOPS complex stability and function. | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | Authors: | Behrmann, H, Gohlke, U, Heinemann, U. | Deposit date: | 2014-08-01 | Release date: | 2014-10-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural Identification of the Vps18 Beta-Propeller Reveals a Critical Role in the Hops Complex Stability and Function. J.Biol.Chem., 289, 2014
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4ULW
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5IFW
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2R80
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![BU of 2r80 by Molmil](/molmil-images/mine/2r80) | Pigeon Hemoglobin (OXY form) | Descriptor: | Hemoglobin subunit alpha-A, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | Authors: | Ponnuswamy, M.N, Packianathan, C, Sundaresan, S, Neelagandan, K, Palani, K, Muller, J.J, Heinemann, U. | Deposit date: | 2007-09-10 | Release date: | 2008-09-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | X-ray crystal structure analysis of Hemolgobin from Pigeon (Columba Livia) at 1.44 angstrom To be Published
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6XYD
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![BU of 6xyd by Molmil](/molmil-images/mine/6xyd) | Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi | Descriptor: | CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ... | Authors: | Roske, Y, Heinemann, U, Andrea, E.D. | Deposit date: | 2020-01-30 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi. J.Struct.Biol., 211, 2020
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3RNT
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![BU of 3rnt by Molmil](/molmil-images/mine/3rnt) | CRYSTAL STRUCTURE OF GUANOSINE-FREE RIBONUCLEASE T1, COMPLEXED WITH VANADATE(V), SUGGESTS CONFORMATIONAL CHANGE UPON SUBSTRATE BINDING | Descriptor: | CALCIUM ION, RIBONUCLEASE T1, VANADATE ION | Authors: | Kostrewa, D, Choe, H.-W, Heinemann, U, Saenger, W. | Deposit date: | 1989-05-31 | Release date: | 1989-10-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of guanosine-free ribonuclease T1, complexed with vanadate (V), suggests conformational change upon substrate binding. Biochemistry, 28, 1989
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7NDH
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![BU of 7ndh by Molmil](/molmil-images/mine/7ndh) | Crystal structure of ZC3H12C PIN domain | Descriptor: | 1,2-ETHANEDIOL, Probable ribonuclease ZC3H12C, SODIUM ION | Authors: | Garg, A, Heinemann, U. | Deposit date: | 2021-02-01 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases. Nucleic Acids Res., 49, 2021
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7NDJ
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7NDI
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![BU of 7ndi by Molmil](/molmil-images/mine/7ndi) | Crystal structure of ZC3H12C PIN domain with Mg2+ Ion | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Probable ribonuclease ZC3H12C, ... | Authors: | Garg, A, Heinemann, U. | Deposit date: | 2021-02-01 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.875 Å) | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases. Nucleic Acids Res., 49, 2021
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7NDK
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![BU of 7ndk by Molmil](/molmil-images/mine/7ndk) | Crystal structure of ZC3H12C PIN catalytic mutant | Descriptor: | Probable ribonuclease ZC3H12C, SODIUM ION | Authors: | Garg, A, Heinemann, U. | Deposit date: | 2021-02-01 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases. Nucleic Acids Res., 49, 2021
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5JDT
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![BU of 5jdt by Molmil](/molmil-images/mine/5jdt) | Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K | Descriptor: | AZIDE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | Deposit date: | 2016-04-17 | Release date: | 2016-09-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling. J.Am.Chem.Soc., 138, 2016
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7ZIH
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![BU of 7zih by Molmil](/molmil-images/mine/7zih) | Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor AG-01-128 | Descriptor: | 8-(1~{H}-benzimidazol-2-ylmethyl)-3-ethyl-7-(phenylmethyl)purine-2,6-dione, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | Authors: | Schuetz, A, Gogolin, A, Pfeifer, J, Mallow, K, Nazare, M, Specker, E, Heinemann, U. | Deposit date: | 2022-04-08 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.46890831 Å) | Cite: | Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem., 65, 2022
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7ZIK
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![BU of 7zik by Molmil](/molmil-images/mine/7zik) | Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor LP533401 | Descriptor: | (2~{R})-2-azanyl-3-[4-[2-azanyl-6-[(1~{R})-1-[4-chloranyl-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]phenyl]propanoic acid, FE (III) ION, Tryptophan 5-hydroxylase 1 | Authors: | Schuetz, A, Heinemann, U. | Deposit date: | 2022-04-08 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.58925915 Å) | Cite: | Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem., 65, 2022
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