4RNS
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![BU of 4rns by Molmil](/molmil-images/mine/4rns) | PcpR inducer binding domain (apo-form) | 分子名称: | PCP degradation transcriptional activation protein | 著者 | Hayes, R.P, Moural, T.W, Lewis, K.M, Onofrei, D, Xun, L, Kang, C. | 登録日 | 2014-10-25 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of the Inducer-Binding Domain of Pentachlorophenol-Degrading Gene Regulator PcpR from Sphingobium chlorophenolicum. Int J Mol Sci, 15, 2014
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4RPO
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![BU of 4rpo by Molmil](/molmil-images/mine/4rpo) | PcpR inducer binding domain (Complex with 2,4,6-trichlorophenol) | 分子名称: | 2,4,6-trichlorophenol, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Hayes, R.P, Moural, T.W, Lewis, K.M, Onofrei, D, Xun, L, Kang, C. | 登録日 | 2014-10-30 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structures of the Inducer-Binding Domain of Pentachlorophenol-Degrading Gene Regulator PcpR from Sphingobium chlorophenolicum. Int J Mol Sci, 15, 2014
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4RPN
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![BU of 4rpn by Molmil](/molmil-images/mine/4rpn) | PcpR inducer binding domain complex with pentachlorophenol | 分子名称: | PCP degradation transcriptional activation protein, PENTACHLOROPHENOL | 著者 | Hayes, R.P, Moural, T.W, Lewis, K.M, Onofrei, D, Xun, L, Kang, C. | 登録日 | 2014-10-30 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.272 Å) | 主引用文献 | Structures of the Inducer-Binding Domain of Pentachlorophenol-Degrading Gene Regulator PcpR from Sphingobium chlorophenolicum. Int J Mol Sci, 15, 2014
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3S2I
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![BU of 3s2i by Molmil](/molmil-images/mine/3s2i) | Crystal Structure of FurX NADH+:Furfuryl alcohol II | 分子名称: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | 登録日 | 2011-05-16 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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5H9F
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![BU of 5h9f by Molmil](/molmil-images/mine/5h9f) | Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution. | 分子名称: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | 著者 | Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A. | 登録日 | 2015-12-28 | 公開日 | 2016-02-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli. Nature, 530, 2016
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7LUF
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![BU of 7luf by Molmil](/molmil-images/mine/7luf) | HSV1 polymerase ternary complex with dsDNA and PNU-183792 | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | 著者 | Hayes, R.P, Klein, D. | 登録日 | 2021-02-22 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
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8DI4
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![BU of 8di4 by Molmil](/molmil-images/mine/8di4) | Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia | 分子名称: | 2-methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine, MAGNESIUM ION, ZINC ION, ... | 著者 | Hayes, R.P, Yan, Y. | 登録日 | 2022-06-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.016 Å) | 主引用文献 | Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia. J.Med.Chem., 66, 2023
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5H9E
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![BU of 5h9e by Molmil](/molmil-images/mine/5h9e) | Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target (32-nt spacer) at 3.20 angstrom resolution. | 分子名称: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | 著者 | Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A. | 登録日 | 2015-12-28 | 公開日 | 2016-02-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli. Nature, 530, 2016
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4HUZ
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![BU of 4huz by Molmil](/molmil-images/mine/4huz) | 2,6-Dichloro-p-hydroquinone 1,2-Dioxygenase | 分子名称: | 2,6-dichloro-p-hydroquinone 1,2-dioxygenase, FE (III) ION, SULFATE ION | 著者 | Hayes, R.P, Nissen, M.S, Green, A.R, Lewis, K.M, Xun, L, Kang, C. | 登録日 | 2012-11-05 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural characterization of 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA) from Sphingobium chlorophenolicum, a new type of aromatic ring-cleavage enzyme. Mol.Microbiol., 88, 2013
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4LBI
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![BU of 4lbi by Molmil](/molmil-images/mine/4lbi) | |
4LBH
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![BU of 4lbh by Molmil](/molmil-images/mine/4lbh) | 5-chloro-2-hydroxyhydroquinone dehydrochlorinase (TftG) from Burkholderia phenoliruptrix AC1100: Apo-form | 分子名称: | 5-chloro-2-hydroxyhydroquinone dehydrochlorinase (TftG), DI(HYDROXYETHYL)ETHER | 著者 | Hayes, R.P, Lewis, K.M, Xun, L, Kang, C. | 登録日 | 2013-06-20 | 公開日 | 2013-08-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Catalytic Mechanism of 5-Chlorohydroxyhydroquinone Dehydrochlorinase from the YCII Superfamily of Largely Unknown Function. J.Biol.Chem., 288, 2013
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4LBP
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![BU of 4lbp by Molmil](/molmil-images/mine/4lbp) | 5-chloro-2-hydroxyhydroquinone dehydrochlorinase (TftG) from Burkholderia phenoliruptrix AC1100: Complex with 2,5-dihydroxybenzoquinone | 分子名称: | 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione, 5-chloro-2-hydroxyhydroquinone dehydrochlorinase (TftG) | 著者 | Hayes, R.P, Lewis, K.M, Xun, L, Kang, C. | 登録日 | 2013-06-20 | 公開日 | 2013-08-28 | 最終更新日 | 2013-10-23 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Catalytic Mechanism of 5-Chlorohydroxyhydroquinone Dehydrochlorinase from the YCII Superfamily of Largely Unknown Function. J.Biol.Chem., 288, 2013
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3S2G
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![BU of 3s2g by Molmil](/molmil-images/mine/3s2g) | Crystal Structure of FurX NADH+:Furfuryl alcohol I | 分子名称: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | 登録日 | 2011-05-16 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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3S1L
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![BU of 3s1l by Molmil](/molmil-images/mine/3s1l) | Crystal Structure of Apo-form FurX | 分子名称: | HEXAETHYLENE GLYCOL, ZINC ION, Zinc-containing alcohol dehydrogenase superfamily | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | 登録日 | 2011-05-15 | 公開日 | 2012-04-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Furfural reduction mechanism of a zinc-dependent alcohol dehydrogenase from Cupriavidus necator JMP134. Mol.Microbiol., 83, 2012
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3S2E
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![BU of 3s2e by Molmil](/molmil-images/mine/3s2e) | Crystal Structure of FurX NADH Complex 1 | 分子名称: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | 登録日 | 2011-05-16 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.763 Å) | 主引用文献 | Crystal Structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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3S2F
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![BU of 3s2f by Molmil](/molmil-images/mine/3s2f) | Crystal Structure of FurX NADH:Furfural | 分子名称: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHORYLISOPROPANE, ... | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | 登録日 | 2011-05-16 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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4G5E
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![BU of 4g5e by Molmil](/molmil-images/mine/4g5e) | 2,4,6-Trichlorophenol 4-monooxygenase | 分子名称: | 2,4,6-Trichlorophenol 4-monooxygenase | 著者 | Hayes, R.P, Webb, B.N, Subramanian, A.K, Nissen, M, Popchock, A, Xun, L, Kang, C. | 登録日 | 2012-07-17 | 公開日 | 2012-09-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Catalytic Differences between Two FADH(2)-Dependent Monooxygenases: 2,4,5-TCP 4-Monooxygenase (TftD) from Burkholderia cepacia AC1100 and 2,4,6-TCP 4-Monooxygenase (TcpA) from Cupriavidus necator JMP134. Int J Mol Sci, 13, 2012
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6Y7C
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![BU of 6y7c by Molmil](/molmil-images/mine/6y7c) | Early cytoplasmic yeast pre-40S particle (purified with Tsr1 as bait) | 分子名称: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Shayan, R, Plassart, L, Plisson-Chastang, C. | 登録日 | 2020-02-28 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Good Vibrations: Structural Remodeling of Maturing Yeast Pre-40S Ribosomal Particles Followed by Cryo-Electron Microscopy. Molecules, 25, 2020
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6OLA
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![BU of 6ola by Molmil](/molmil-images/mine/6ola) | Structure of the PCV2d virus-like particle | 分子名称: | Capsid protein, DNA (5'-D(P*CP*CP*GP*G)-3') | 著者 | Khayat, R, Wen, K, Alimova, A, Galarza, J, Gottlieb, P. | 登録日 | 2019-04-16 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural characterization of the PCV2d virus-like particle at 3.3 angstrom resolution reveals differences to PCV2a and PCV2b capsids, a tetranucleotide, and an N-terminus near the icosahedral 3-fold axes. Virology, 537, 2019
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1NJT
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![BU of 1njt by Molmil](/molmil-images/mine/1njt) | COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | 分子名称: | CHLORIDE ION, Capsid protein P40, Peptidomimetic Inhibitor | 著者 | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | 登録日 | 2003-01-02 | 公開日 | 2003-02-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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6RBD
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![BU of 6rbd by Molmil](/molmil-images/mine/6rbd) | State 1 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles | 分子名称: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C. | 登録日 | 2019-04-10 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism. Nat Commun, 10, 2019
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6RBE
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![BU of 6rbe by Molmil](/molmil-images/mine/6rbe) | State 2 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C. | 登録日 | 2019-04-10 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism. Nat Commun, 10, 2019
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1NJU
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![BU of 1nju by Molmil](/molmil-images/mine/1nju) | Complex structure of HCMV Protease and a peptidomimetic inhibitor | 分子名称: | Assemblin, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | 著者 | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | 登録日 | 2003-01-02 | 公開日 | 2003-02-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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1NKM
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![BU of 1nkm by Molmil](/molmil-images/mine/1nkm) | Complex structure of HCMV Protease and a peptidomimetic inhibitor | 分子名称: | Assemblin, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | 著者 | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | 登録日 | 2003-01-03 | 公開日 | 2003-02-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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1NKK
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![BU of 1nkk by Molmil](/molmil-images/mine/1nkk) | COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | 分子名称: | Capsid protein P40, Peptidomimetic inhibitor | 著者 | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | 登録日 | 2003-01-03 | 公開日 | 2003-02-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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