1GQ0
 
 | | Solution structure of Antiamoebin I, a membrane channel-forming polypeptide; NMR, 20 structures | | 分子名称: | ANTIAMOEBIN I | | 著者 | Galbraith, T.P, Harris, R, Driscoll, P.C, Wallace, B.A. | | 登録日 | 2001-11-16 | | 公開日 | 2003-01-24 | | 最終更新日 | 2017-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR studies of antiamoebin, a membrane channel-forming polypeptide.
Biophys. J., 84, 2003
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1JM6
 | | Pyruvate dehydrogenase kinase, isozyme 2, containing ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pyruvate dehydrogenase kinase, ... | | 著者 | Steussy, C.N, Popov, K.M, Bowker-Kinley, M.M, Sloan, R.B, Harris, R.A, Hamilton, J.A. | | 登録日 | 2001-07-17 | | 公開日 | 2001-10-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of pyruvate dehydrogenase kinase. Novel folding pattern for a serine protein kinase.
J.Biol.Chem., 276, 2001
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7TGR
 | | Structure of SARS-CoV-2 main protease in complex with GC376 | | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 1,2-ETHANEDIOL, ... | | 著者 | Esler, M.A, Shi, K, Aihara, H, Harris, R.S. | | 登録日 | 2022-01-09 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells.
Mbio, 13, 2022
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1IG3
 | | Mouse Thiamin Pyrophosphokinase Complexed with Thiamin | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, SULFATE ION, thiamin pyrophosphokinase | | 著者 | Timm, D.E, Liu, J, Baker, L.-J, Harris, R.A. | | 登録日 | 2001-04-16 | | 公開日 | 2001-04-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of thiamin pyrophosphokinase.
J.Mol.Biol., 310, 2001
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2MZZ
 | | NMR structure of APOBEC3G NTD variant, sNTD | | 分子名称: | Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G variant, ZINC ION | | 著者 | Kouno, T, Luengas, E.M, Shigematu, M, Shandilya, S.M.D, Zhang, J, Chen, L, Hara, M, Schiffer, C.A, Harris, R.S, Matsuo, H. | | 登録日 | 2015-02-28 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.
Nat.Struct.Mol.Biol., 22, 2015
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1ZHB
 | | Crystal Structure Of The Murine Class I Major Histocompatibility Complex Of H-2Db, B2-Microglobulin, and a 9-Residue Peptide Derived from rat dopamine beta-monooxigenase | | 分子名称: | 9-mer peptide from Dopamine beta-monooxygenase, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Sandalova, T, Michaelsson, J, Harris, R.A, Odeberg, J, Schneider, G, Karre, K, Achour, A. | | 登録日 | 2005-04-25 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity
J.Biol.Chem., 280, 2005
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1IG0
 | | Crystal Structure of yeast Thiamin Pyrophosphokinase | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Thiamin pyrophosphokinase | | 著者 | Baker, L.-J, Dorocke, J.A, Harris, R.A, Timm, D.E. | | 登録日 | 2001-04-16 | | 公開日 | 2001-06-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of yeast thiamin pyrophosphokinase.
Structure, 9, 2001
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2K2O
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4HFH
 | | The GLIC pentameric Ligand-Gated Ion Channel (wild-type) complexed to bromoform | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. | | 登録日 | 2012-10-05 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nat Commun, 4, 2013
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4HFB
 | | The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant (Apo) | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. | | 登録日 | 2012-10-05 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nat Commun, 4, 2013
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4HFD
 | | The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to bromoform | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. | | 登録日 | 2012-10-05 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nat Commun, 4, 2013
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2JYW
 | | Solution structure of C-terminal domain of APOBEC3G | | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | 著者 | Chen, K, Harjes, E, Gross, P.J, Fahmy, A, Lu, Y, Shindo, K, Harris, R.S, Matsuo, H. | | 登録日 | 2007-12-20 | | 公開日 | 2008-02-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.
Nature, 452, 2008
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4HFC
 | | The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to 2-bromo-ethanol | | 分子名称: | 2-BROMOETHANOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. | | 登録日 | 2012-10-05 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nat Commun, 4, 2013
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2JVE
 | | Solution structure of the extracellular domain of Prod1, a protein implicated in proximodistal identity during amphibian limb regeneration | | 分子名称: | Prod 1 | | 著者 | Garza-Garcia, A, Harris, R, Esposito, D, Driscoll, P.C. | | 登録日 | 2007-09-19 | | 公開日 | 2008-09-30 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration.
Plos One, 4, 2009
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1LR1
 | | Solution Structure of the Oligomerization Domain of the Bacterial Chromatin-Structuring Protein H-NS | | 分子名称: | dna-binding protein h-ns | | 著者 | Esposito, D, Petrovic, A, Harris, R, Ono, S, Eccleston, J, Mbabaali, A, Haq, I, Higgins, C.F, Hinton, J.C.D, Driscoll, P.C, Ladbury, J.E. | | 登録日 | 2002-05-14 | | 公開日 | 2003-01-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | H-NS Oligomerization Domain Structure Reveals the Mechanism for High Order
Self-association of the Intact Protein
J.Mol.Biol., 324, 2002
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4HFE
 | | The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to ethanol | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Sauguet, L, Howard, R.J, Malherbe, L, Lee, U.S, Corringer, P.J, Harris, R.A, Delarue, M. | | 登録日 | 2012-10-05 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nat Commun, 4, 2013
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2JP0
 | | Solution structure of the N-terminal extraceullular domain of the lymphocyte receptor CD5 calculated using inferential structure determination (ISD) | | 分子名称: | T-cell surface glycoprotein CD5 | | 著者 | Garza-Garcia, A, Harris, R, Esposito, D, Driscoll, P.C, Rieping, W. | | 登録日 | 2007-04-16 | | 公開日 | 2008-02-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure and conformational plasticity of the N-terminal scavenger receptor cysteine-rich domain of human CD5
J.Mol.Biol., 378, 2008
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2JOP
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4J71
 | | Crystal Structure of GSK3b in complex with inhibitor 1R | | 分子名称: | (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, CHLORIDE ION, Glycogen synthase kinase-3 beta, ... | | 著者 | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-12 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
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1N59
 | | Crystal structure of the Murine class I Major Histocompatibility Complex of H-2KB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | | 著者 | Achour, A, Michaelsson, J, Harris, R.A, Odeberg, J, Grufman, P, Sandberg, J.K, Levitsky, V, Karre, K, Sandalova, T, Schneider, G. | | 登録日 | 2002-11-05 | | 公開日 | 2003-01-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | A Structural Basis for LCMV Immune Evasion. Subversion of H-2D(b) and H-2K(b) Presentation of gp33
Revealed by Comparative Crystal Structure Analyses.
Immunity, 17, 2002
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1N5A
 | | Crystal structure of the Murine class I Major Histocompatibility Complex of H-2DB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV | | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | 著者 | Achour, A, Michaelsson, J, Harris, R.A, Odeberg, J, Grufman, P, Sandberg, J.K, Levitsky, V, Karre, K, Sandalova, T, Schneider, G. | | 登録日 | 2002-11-05 | | 公開日 | 2003-01-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A Structural Basis for LCMV Immune Evasion. Subversion of H-2D(b) and H-2K(b) Presentation of
gp33 Revealed by Comparative Crystal Structure Analyses.
Immunity, 17, 2002
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4J1R
 | | Crystal Structure of GSK3b in complex with inhibitor 15R | | 分子名称: | (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ... | | 著者 | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-01 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
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1WA1
 | | Crystal Structure Of H313Q Mutant Of Alcaligenes Xylosoxidans Nitrite Reductase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ... | | 著者 | Barrett, M.L, Harris, R.L, Antonyuk, S.V, Strange, R.W, Hough, M.A, Eady, R.R, Sawers, G, Hasnain, S.S. | | 登録日 | 2004-10-22 | | 公開日 | 2005-01-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Insights Into Redox Partner Interactions and Substrate Binding in Nitrite Reductase from Alcaligenes Xylosoxidans: Crystal Structures of the Trp138His and His313Gln Mutants
Biochemistry, 43, 2004
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1WA0
 | | Crystal Structure Of W138H Mutant Of Alcaligenes Xylosoxidans Nitrite Reductase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ... | | 著者 | Barrett, M.L, Harris, R.L, Antonyuk, S.V, Strange, R.W, Hough, M.A, Eady, R.R, Sawers, G, Hasnain, S.S. | | 登録日 | 2004-10-22 | | 公開日 | 2005-01-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Insights Into Redox Partner Interactions and Substrate Binding in Nitrite Reductase from Alcaligenes Xylosoxidans: Crystal Structures of the Trp138His and His313Gln Mutants
Biochemistry, 43, 2004
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1WA2
 | | Crystal Structure Of H313Q Mutant Of Alcaligenes Xylosoxidans Nitrite Reductase with nitrite bound | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE,, ... | | 著者 | Barrett, M.L, Harris, R.L, Antonyuk, S.V, Strange, R.W, Hough, M.A, Eady, R.R, Sawers, G, Hasnain, S.S. | | 登録日 | 2004-10-22 | | 公開日 | 2005-01-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Insights Into Redox Partner Interactions and Substrate Binding in Nitrite Reductase from Alcaligenes Xylosoxidans: Crystal Structures of the Trp138His and His313Gln Mutants
Biochemistry, 43, 2004
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