7X0E
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![BU of 7x0e by Molmil](/molmil-images/mine/7x0e) | Structure of Pseudomonas NRPS protein, AmbB-TC in apo form | Descriptor: | AMB antimetabolite synthase AmbB, N-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentakis(oxidanyl)hexyl]nonanamide | Authors: | ChuYuanKee, M, Bharath, S.R, Song, H. | Deposit date: | 2022-02-22 | Release date: | 2022-07-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB. Sci Rep, 12, 2022
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8I3Y
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![BU of 8i3y by Molmil](/molmil-images/mine/8i3y) | Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA. | Descriptor: | CALCIUM ION, SUCCINIC ACID, SUCCINYL-COENZYME A, ... | Authors: | Mochizuki, K, Inaoka, D.K, Fukuda, K, Kurasawa, H, Iyoda, K, Nakai, U, Harada, S, Balogun, E.O, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Hirayama, K, Kita, K, Shiba, T. | Deposit date: | 2023-01-18 | Release date: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA. To Be Published
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8I40
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![BU of 8i40 by Molmil](/molmil-images/mine/8i40) | Crystal structure of ASCT from Trypanosoma brucei in complex with CoA. | Descriptor: | ACETATE ION, CALCIUM ION, COENZYME A, ... | Authors: | Mochizuki, K, Inaoka, D.K, Fukuda, K, Kurasawa, H, Iyoda, K, Nakai, U, Harada, S, Balogun, E.O, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Hirayama, K, Kita, K, Shiba, T. | Deposit date: | 2023-01-18 | Release date: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal structure of ligand complexes of ASCT from Trypanosoma brucei and molecular mechanism in comparison with mammalian SCOT. To Be Published
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5XX1
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![BU of 5xx1 by Molmil](/molmil-images/mine/5xx1) | Crystal structure of Arginine decarboxylase (AdiA) from Salmonella typhimurium | Descriptor: | Arginine decarboxylase, PHOSPHATE ION | Authors: | Deka, G, Bharath, S.R, Shavithri, H.S, Murthy, M.R.N. | Deposit date: | 2017-06-30 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural studies on the decameric S. typhimurium arginine decarboxylase (ADC): Pyridoxal 5'-phosphate binding induces conformational changes Biochem. Biophys. Res. Commun., 490, 2017
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5X30
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![BU of 5x30 by Molmil](/molmil-images/mine/5x30) | Crystal structure of Pseudomonas putida methionine gamma-lyase C116H mutant with L-homocysteine intermediates. | Descriptor: | (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, (2~{S})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-sulfanyl-butanoic acid, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... | Authors: | Shiba, T, Sato, D, Harada, S. | Deposit date: | 2017-02-02 | Release date: | 2017-04-12 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
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4XGM
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![BU of 4xgm by Molmil](/molmil-images/mine/4xgm) | |
1X26
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![BU of 1x26 by Molmil](/molmil-images/mine/1x26) | Solution structure of the AA-mismatch DNA complexed with naphthyridine-azaquinolone | Descriptor: | 5'-D(*CP*AP*TP*TP*CP*AP*GP*TP*TP*AP*G)-3', 5'-D(*CP*TP*AP*AP*CP*AP*GP*AP*AP*TP*G)-3', N~3~-{3-[(7-METHYL-1,8-NAPHTHYRIDIN-2-YL)AMINO]-3-OXOPROPYL}-N~1~-[(7-OXO-7,8-DIHYDRO-1,8-NAPHTHYRIDIN-2-YL)METHYL]-BET A-ALANINAMIDE | Authors: | Nakatani, K, Hagihara, S, Goto, Y, Kobori, A, Hagihara, M, Hayashi, G, Kyo, M, Nomura, M, Mishima, M, Kojima, C. | Deposit date: | 2005-04-20 | Release date: | 2006-04-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide repeats Nat.Chem.Biol., 1, 2005
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4XGL
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5YJX
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![BU of 5yjx by Molmil](/molmil-images/mine/5yjx) | Structure of the Ndi1 protein from Saccharomyces cerevisiae in complex with myxothiazol. | Descriptor: | (2Z,6E)-7-{2'-[(2E,4E)-1,6-DIMETHYLHEPTA-2,4-DIENYL]-2,4'-BI-1,3-THIAZOL-4-YL}-3,5-DIMETHOXY-4-METHYLHEPTA-2,6-DIENAMID E, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Yamasita, T, Inaoka, D.K, Shiba, T, Oohashi, T, Iwata, S, Yagi, T, Kosaka, H, Harada, S, Kita, K, Hirano, K. | Deposit date: | 2017-10-11 | Release date: | 2018-02-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors Sci Rep, 8, 2018
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5YJY
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![BU of 5yjy by Molmil](/molmil-images/mine/5yjy) | Structure of the Ndi1 protein from Saccharomyces cerevisiae in complex with AC0-12. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-dodecyl-1-oxidanidyl-quinolin-1-ium-4-ol, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Yamasita, T, Inaoka, D.K, Shiba, T, Oohashi, T, Iwata, S, Yagi, T, Kosaka, H, Harada, S, Kita, K, Hirano, K. | Deposit date: | 2017-10-11 | Release date: | 2018-02-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors Sci Rep, 8, 2018
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5YJW
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![BU of 5yjw by Molmil](/molmil-images/mine/5yjw) | Structure of the Ndi1 protein from Saccharomyces cerevisiae in complex with the competitive inhibitor, stigmatellin. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yamasita, T, Inaoka, D.K, Shiba, T, Oohashi, T, Iwata, S, Yagi, T, Kosaka, H, Harada, S, Kita, K, Hirano, K. | Deposit date: | 2017-10-11 | Release date: | 2018-02-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors Sci Rep, 8, 2018
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5ZDR
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![BU of 5zdr by Molmil](/molmil-images/mine/5zdr) | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative | Descriptor: | 3-chloro-4,6-dihydroxy-5-[(2E,6E,8S)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | Authors: | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | Deposit date: | 2018-02-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg, 1860, 2019
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5ZDQ
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![BU of 5zdq by Molmil](/molmil-images/mine/5zdq) | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with COLLETOCHLORIN B | Descriptor: | 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | Authors: | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | Deposit date: | 2018-02-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg, 1860, 2019
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5ZDP
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![BU of 5zdp by Molmil](/molmil-images/mine/5zdp) | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ferulenol | Descriptor: | 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one, Alternative oxidase, mitochondrial, ... | Authors: | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | Deposit date: | 2018-02-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg, 1860, 2019
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5X2W
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5X2Z
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![BU of 5x2z by Molmil](/molmil-images/mine/5x2z) | |
5X2X
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7ED9
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![BU of 7ed9 by Molmil](/molmil-images/mine/7ed9) | Crystal structure of selenomethionine-labeled Thermus thermophilus FakA ATP-binding domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable kinase | Authors: | Nakatani, M, Nakahara, S, Fukui, K, Murakawa, T, Masui, R. | Deposit date: | 2021-03-15 | Release date: | 2022-03-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.01764154 Å) | Cite: | Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8. J.Struct.Biol., 214, 2022
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7UN5
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![BU of 7un5 by Molmil](/molmil-images/mine/7un5) | |
7UMQ
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![BU of 7umq by Molmil](/molmil-images/mine/7umq) | |
6AJ6
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![BU of 6aj6 by Molmil](/molmil-images/mine/6aj6) | Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADP+ | Descriptor: | Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wang, X, Inaoka, D.K, Shiba, T, Balogun, E.O, Ziebart, N, Allman, S, Watanabe, Y, Nozaki, T, Boshart, M, Bringaud, F, Harada, S, Kita, K. | Deposit date: | 2018-08-27 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Biochemical characterization of a novel Trypanosoma brucei glycosomal isocitrate dehydrogenase with dual coenzyme specificity (NADP+/NAD+) To Be Published
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5X2V
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5X2Y
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7ED6
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![BU of 7ed6 by Molmil](/molmil-images/mine/7ed6) | Crystal structure of Thermus thermophilus FakA ATP-binding domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable kinase | Authors: | Nakatani, M, Nakahara, S, Fukui, K, Murakawa, T, Masui, R. | Deposit date: | 2021-03-15 | Release date: | 2022-03-16 | Last modified: | 2023-01-11 | Method: | X-RAY DIFFRACTION (1.92850327 Å) | Cite: | Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8. J.Struct.Biol., 214, 2022
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7CII
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![BU of 7cii by Molmil](/molmil-images/mine/7cii) | Crystal structure of L-methionine decarboxylase from Streptomyces sp.590 in complexed with L- methionine methyl ester (external aldimine form). | Descriptor: | L-methionine decarboxylase, methyl (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-4-methylsulfanyl-butanoate | Authors: | Okawa, A, Shiba, T, Hayashi, M, Onoue, Y, Murota, M, Sato, D, Inagaki, J, Tamura, T, Harada, S, Inagaki, K. | Deposit date: | 2020-07-07 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structural basis for substrate specificity of l-methionine decarboxylase. Protein Sci., 30, 2021
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