7CII

Crystal structure of L-methionine decarboxylase from Streptomyces sp.590 in complexed with L- methionine methyl ester (external aldimine form).

Summary for 7CII

• Entry DOI: 10.2210/pdb7cii/pdb
• Descriptor: L-methionine decarboxylase, methyl (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-4-methylsulfanyl-butanoate (3 entities in total)
• Functional Keywords: decarboxylase, plp-dependent enzymes, lyase
• Biological source: Streptomyces sp. 590 KI-2014
• Total number of polymer chains: 2
• Total formula weight: 123738.93

Authors

Okawa, A.,Shiba, T.,Hayashi, M.,Onoue, Y.,Murota, M.,Sato, D.,Inagaki, J.,Tamura, T.,Harada, S.,Inagaki, K. (deposition date: 2020-07-07, release date: 2021-01-27, Last modification date: 2023-11-29)

• Primary citation: Okawa, A.,Shiba, T.,Hayashi, M.,Onoue, Y.,Murota, M.,Sato, D.,Inagaki, J.,Tamura, T.,Harada, S.,Inagaki, K.; Structural basis for substrate specificity of l-methionine decarboxylase.; Protein Sci., 30:663-677, 2021; PubMed: 33452696; DOI: 10.1002/pro.4027

Experimental method

X-RAY DIFFRACTION (1.51 Å)