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PDB: 63 件

6IOK
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Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state)
分子名称: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM
著者Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E.
登録日2018-10-30
公開日2019-04-03
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Nat Commun, 10, 2019
2RU6
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The pure alternative state of ubiquitin
分子名称: Ubiquitin
著者Kitazawa, S, Kameda, T, Kumo, A, Utsumi, M, Baxter, N, Kato, K, Williamson, M.P, Kitahara, R.
登録日2013-12-04
公開日2014-02-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Close Identity between Alternatively Folded State N2 of Ubiquitin and the Conformation of the Protein Bound to the Ubiquitin-Activating Enzyme
Biochemistry, 53, 2014
2RSU
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Alternative structure of Ubiquitin
分子名称: Ubiquitin
著者Kitazawa, S, Kameda, T, Yagi-Utsumi, M, Kato, K, Kitahara, R.
登録日2012-06-15
公開日2013-03-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Q41N Variant of Ubiquitin as a Model for the Alternatively Folded N2 State of Ubiquitin
Biochemistry, 52, 2013
5GHK
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Crystal Structure Analysis of Canine serum albumin
分子名称: Serum albumin
著者Kihira, K, Yamada, K, Kureishi, M, Yokomaku, K, Shinohara, R, Akiyama, M, Komatsu, T.
登録日2016-06-20
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Artificial Blood for Dogs
Sci Rep, 6, 2016
4JP8
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Crystal structure of Pro-F17H/S324A
分子名称: CALCIUM ION, Tk-subtilisin
著者Yuzaki, K, You, D.J, Uehara, R, Koga, Y, Kanaya, S.
登録日2013-03-19
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Increase in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domain
Protein Sci., 22, 2013
4JXI
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Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, BROMIDE ION, GLYCEROL, ...
著者Kuzin, A, Smith, M.D, Richter, F, Lew, S, Seetharaman, R, Bryan, C, Lech, Z, Kiss, G, Moretti, R, Maglaqui, M, Xiao, R, Kohan, E, Smith, M, Everett, J.K, Nguyen, R, Pande, V, Hilvert, D, Kornhaber, G, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2013-03-28
公開日2013-05-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184
To be Published
3SN6
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Crystal structure of the beta2 adrenergic receptor-Gs protein complex
分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid antibody VHH fragment, Endolysin,Beta-2 adrenergic receptor, ...
著者Rasmussen, S.G.F, DeVree, B.T, Zou, Y, Kruse, A.C, Chung, K.Y, Kobilka, T.S, Thian, F.S, Chae, P.S, Pardon, E, Calinski, D, Mathiesen, J.M, Shah, S.T.A, Lyons, J.A, Caffrey, M, Gellman, S.H, Steyaert, J, Skiniotis, G, Weis, W.I, Sunahara, R.K, Kobilka, B.K.
登録日2011-06-28
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Nature, 477, 2011
3WCU
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The structure of a deoxygenated 400 kda hemoglobin provides a more accurate description of the cooperative mechanism of giant hemoglobins: Deoxygenated form
分子名称: A1 globin chain of giant V2 hemoglobin, A2 globin chain of giant V2 hemoglobin, B1 globin chain of giant V2 hemoglobin, ...
著者Numoto, N, Nakagawa, T, Ohara, R, Hasegawa, T, Kita, A, Yoshida, T, Maruyama, T, Imai, K, Fukumori, Y, Miki, K.
登録日2013-06-01
公開日2014-06-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of a deoxygenated 400 kDa haemoglobin reveals ternary- and quaternary-structural changes of giant haemoglobins
Acta Crystallogr.,Sect.D, 70, 2014
3WCV
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The structure of a deoxygenated 400 kda hemoglobin provides a more accurate description of the cooperative mechanism of giant hemoglobins: CA bound form
分子名称: A1 globin chain of giant V2 hemoglobin, A2 globin chain of giant V2 hemoglobin, B1 globin chain of giant V2 hemoglobin, ...
著者Numoto, N, Nakagawa, T, Ohara, R, Hasegawa, T, Kita, A, Yoshida, T, Maruyama, T, Imai, K, Fukumori, Y, Miki, K.
登録日2013-06-01
公開日2014-06-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of a deoxygenated 400 kDa haemoglobin reveals ternary- and quaternary-structural changes of giant haemoglobins
Acta Crystallogr.,Sect.D, 70, 2014
3WCW
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The structure of a deoxygenated 400 kda hemoglobin provides a more accurate description of the cooperative mechanism of giant hemoglobins: MG bound form
分子名称: A1 globin chain of giant V2 hemoglobin, A2 globin chain of giant V2 hemoglobin, B1 globin chain of giant V2 hemoglobin, ...
著者Numoto, N, Nakagawa, T, Ohara, R, Hasegawa, T, Kita, A, Yoshida, T, Maruyama, T, Imai, K, Fukumori, Y, Miki, K.
登録日2013-06-01
公開日2014-06-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of a deoxygenated 400 kDa haemoglobin reveals ternary- and quaternary-structural changes of giant haemoglobins
Acta Crystallogr.,Sect.D, 70, 2014
3WCT
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The structure of a deoxygenated 400 kda hemoglobin provides a more accurate description of the cooperative mechanism of giant hemoglobins: Oxygenated form
分子名称: A1 globin chain of giant V2 hemoglobin, A2 globin chain of giant V2 hemoglobin, B1 globin chain of giant V2 hemoglobin, ...
著者Numoto, N, Nakagawa, T, Ohara, R, Hasegawa, T, Kita, A, Yoshida, T, Maruyama, T, Imai, K, Fukumori, Y, Miki, K.
登録日2013-06-01
公開日2014-06-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of a deoxygenated 400 kDa haemoglobin reveals ternary- and quaternary-structural changes of giant haemoglobins
Acta Crystallogr.,Sect.D, 70, 2014
3PDS
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Irreversible Agonist-Beta2 Adrenoceptor Complex
分子名称: 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one, CHOLESTEROL, Fusion protein Beta-2 adrenergic receptor/Lysozyme, ...
著者Rosenbaum, D.M, Zhang, C, Lyons, J.A, Holl, R, Aragao, D, Arlow, D.H, Rasmussen, S.G.F, Choi, H.-J, DeVree, B.T, Sunahara, R.K, Chae, P.S, Gellman, S.H, Dror, R.O, Shaw, D.E, Weis, W.I, Caffrey, M, Gmeiner, P, Kobilka, B.K.
登録日2010-10-24
公開日2011-01-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure and function of an irreversible agonist-beta(2) adrenoceptor complex
Nature, 469, 2011
3P0G
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Structure of a nanobody-stabilized active state of the beta2 adrenoceptor
分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor, Lysozyme, ...
著者Rasmussen, S.G.F, Choi, H.-J, Fung, J.J, Pardon, E, Casarosa, P, Chae, P.S, DeVree, B.T, Rosenbaum, D.M, Thian, F.S, Kobilka, T.S, Schnapp, A, Konetzki, I, Sunahara, R.K, Gellman, S.H, Pautsch, A, Steyaert, J, Weis, W.I, Kobilka, B.K.
登録日2010-09-28
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
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