7YAC
 
 | | Paltusotine-bound SSTR2-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Zhao, J, Shao, Z. | | 登録日 | 2022-06-27 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine.
Nat Commun, 14, 2023
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7YAE
 | | Octreotide-bound SSTR2-Gi complex | | 分子名称: | CHOLESTEROL, DPN-CYS-PHE-DTR-LYS-THR-CYS-THO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhao, J, Shao, Z. | | 登録日 | 2022-06-28 | | 公開日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine.
Nat Commun, 14, 2023
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5J2Y
 | | Molecular insight into the regulatory mechanism of the quorum-sensing repressor RsaL in Pseudomonas aeruginosa | | 分子名称: | DNA (26-MER), Regulatory protein | | 著者 | Zhao, J, Gan, J, Zhang, J, Kang, H, Kong, W, Zhu, M, Li, F, Song, Y, Qin, J, Liang, H. | | 登録日 | 2016-03-30 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of Pseudomonas aeruginosa RsaL bound to promoter DNA reaffirms its role as a global regulator involved in quorum-sensing.
Nucleic Acids Res., 45, 2017
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6Z71
 | | Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2020-05-29 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6Z70
 | | Structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2020-05-29 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8V02
 | | AaegOR10 structure bound to o-cresol | | 分子名称: | Odorant receptor OR10, Odorant receptor Orco, o-cresol | | 著者 | Zhao, J, del Marmol, J. | | 登録日 | 2023-11-16 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of odor sensing by insect heteromeric odorant receptors.
Science, 384, 2024
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8V00
 | | AaegOR10 apo structure | | 分子名称: | Odorant receptor OR10, Odorant receptor Orco | | 著者 | Zhao, J, del Marmol, J. | | 登録日 | 2023-11-16 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural basis of odor sensing by insect heteromeric odorant receptors.
Science, 384, 2024
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8V3C
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8V3D
 | | AgamOR28 structure bound to 2,4,5-trimethylthiazole | | 分子名称: | 2,4,5-trimethyl-1,3-thiazole, OR28, Odorant receptor Orco | | 著者 | Zhao, J, del Marmol, J. | | 登録日 | 2023-11-27 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structural basis of odor sensing by insect heteromeric odorant receptors.
Science, 384, 2024
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6FV7
 | | Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2018-03-01 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Dimer structure of Aq128 in the outward-facing state
To Be Published
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6FV6
 | | Monomer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2018-03-01 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Monomer structure of Aq128 in the outward-facing state
To Be Published
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6FV8
 | | Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state | | 分子名称: | Aq128 | | 著者 | Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H. | | 登録日 | 2018-03-01 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Dimer structure of the MATE family multidrug resistance transporter Aq128
in the outward-facing state
To Be Published
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6V9Y
 | | Structure of TRPA1 bound with A-967079, PMAL-C8 | | 分子名称: | Transient receptor potential cation channel subfamily A member 1 | | 著者 | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Nature, 585, 2020
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6V9X
 | | Structure of TRPA1 modified by iodoacetamide, PMAL-C8 | | 分子名称: | Transient receptor potential cation channel subfamily A member 1 | | 著者 | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-06 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Nature, 585, 2020
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6V9V
 | | Structure of TRPA1 modified by Bodipy-iodoacetamide with bound calcium, LMNG | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily A member 1, ~{N}-[[2,2-bis(fluoranyl)-10,12-dimethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-4-yl]methyl]ethanamide | | 著者 | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-06 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Nature, 585, 2020
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6V9W
 | | Structure of TRPA1 (ligand-free) with bound calcium, LMNG | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily A member 1 | | 著者 | Zhao, J, Lin King, J.V, Paulsen, C.E, Cheng, Y, Julius, D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Nature, 585, 2020
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7NAQ
 | | Human PA200-20S proteasome complex | | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... | | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | 登録日 | 2021-06-22 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAP
 | | Human PA28-20S-PA28 proteasome complex | | 分子名称: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | 登録日 | 2021-06-22 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAO
 | | Human PA28-20S proteasome complex | | 分子名称: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | 登録日 | 2021-06-22 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAN
 | | Human 20S proteasome core particle | | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | 著者 | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | 登録日 | 2021-06-22 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5I8I
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3J9T
 | | Yeast V-ATPase state 1 | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Zhao, J, Benlekbir, S, Rubinstein, J.L. | | 登録日 | 2015-02-23 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
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3J9V
 | | Yeast V-ATPase state 3 | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Zhao, J, Benlekbir, S, Rubinstein, J.L. | | 登録日 | 2015-02-23 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | | 主引用文献 | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
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8CVT
 | | Human 19S-20S proteasome, state SD2 | | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | | 著者 | Zhao, J. | | 登録日 | 2022-05-18 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8CVR
 | | Human 20S proteasome with MG-132 | | 分子名称: | N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | 著者 | Zhao, J. | | 登録日 | 2022-05-18 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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