8CVR

Human 20S proteasome with MG-132

Summary for 8CVR

Entry DOI	10.2210/pdb8cvr/pdb
EMDB information	27013 27014 27015 27016 27017 27018 27019
Descriptor	Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (15 entities in total)
Functional Keywords	proteolysis, protein degradation, complex, inhibitor, mg-132, mg132, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Homo sapiens (human) More
Total number of polymer chains	28
Total formula weight	736124.76
Authors	Zhao, J. (deposition date: 2022-05-18, release date: 2022-11-02)
Primary citation	Zhao, J.,Makhija, S.,Zhou, C.,Zhang, H.,Wang, Y.,Muralidharan, M.,Huang, B.,Cheng, Y. Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119:e2207200119-e2207200119, 2022 Cited by PubMed: 35858375 DOI: 10.1073/pnas.2207200119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation