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PDB: 2350 件

2R85
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Crystal structure of PurP from Pyrococcus furiosus complexed with AMP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-10
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R86
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Crystal structure of PurP from Pyrococcus furiosus complexed with ATP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-10
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R7K
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BU of 2r7k by Molmil
Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMPPCP and AICAR
分子名称: 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, CHLORIDE ION, ...
著者Zhang, Y, White, R.H, Ealick, S.E.
登録日2007-09-09
公開日2007-12-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
6L2C
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BU of 6l2c by Molmil
Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA
分子名称: Acetyl-CoA-acetyltransferase, putative, COENZYME A
著者Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W.
登録日2019-10-03
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
6KQF
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BU of 6kqf by Molmil
Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt
分子名称: DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Li, L, Ebright, R.H.
登録日2019-08-17
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
3OGG
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BU of 3ogg by Molmil
Crystal structure of the receptor binding domain of botulinum neurotoxin D
分子名称: Botulinum neurotoxin type D
著者Zhang, Y, Gao, X, Qin, L, Buchko, G.W, Robinson, H, Varnum, S.M.
登録日2010-08-16
公開日2010-09-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D.
Biochem.Biophys.Res.Commun., 401, 2010
4L12
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Crystal structure of EGFP-based Calcium Sensor CatchER complexed with Gd
分子名称: EGFP-based Calcium Sensor CatchER, GADOLINIUM ATOM
著者Zhang, Y, Weber, I.T.
登録日2013-06-01
公開日2013-12-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr.,Sect.D, 69, 2013
2P72
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crystal structure of a glycosyltransferase involved in the glycosylation of the major capsid of PBCV-1
分子名称: MANGANESE (II) ION, Putative glycosyltransferase (Mannosyltransferase) involved in glycosylating the PBCV-1 major capsid protein, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Zhang, Y, Xiang, Y, Van Etten, J.L, Rossmann, M.G.
登録日2007-03-19
公開日2007-08-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of a chlorella virus-encoded glycosyltransferase.
Structure, 15, 2007
2P73
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crystal structure of a glycosyltransferase involved in the glycosylation of the major capsid of PBCV-1
分子名称: MANGANESE (II) ION, Putative glycosyltransferase (Mannosyltransferase) involved in glycosylating the PBCV-1 major capsid protein, URIDINE-5'-DIPHOSPHATE
著者Zhang, Y, Xiang, Y, Van Etten, J.L, Rossmann, M.G.
登録日2007-03-19
公開日2007-08-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and function of a chlorella virus-encoded glycosyltransferase.
Structure, 15, 2007
2A8Y
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BU of 2a8y by Molmil
Crystal structure of 5'-deoxy-5'methylthioadenosine phosphorylase complexed with 5'-deoxy-5'methylthioadenosine and sulfate
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5'-methylthioadenosine phosphorylase (mtaP), SULFATE ION
著者Zhang, Y, Porcelli, M, Cacciapuoti, G, Ealick, S.E.
登録日2005-07-10
公開日2006-03-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase II from Sulfolobus solfataricus, a thermophilic enzyme stabilized by intramolecular disulfide bonds.
J.Mol.Biol., 357, 2006
2MNY
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BU of 2mny by Molmil
NMR Structure of KDM5B PHD1 finger
分子名称: Lysine-specific demethylase 5B, ZINC ION
著者Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C.
登録日2014-04-16
公開日2014-08-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B.
Protein Cell, 5, 2014
4NPU
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BU of 4npu by Molmil
Crystal Structure of HIV-1 Protease Multiple Mutant P51
分子名称: Protease
著者Zhang, Y, Weber, I.T.
登録日2013-11-22
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps.
Acs Chem.Biol., 9, 2014
7XRJ
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BU of 7xrj by Molmil
crystal structure of N-acetyltransferase DgcN-25328
分子名称: Putative NAD-dependent epimerase/dehydratase family protein, SULFATE ION
著者Zhang, Y.Z, Yu, Y, Cao, H.Y, Chen, X.L, Wang, P.
登録日2022-05-10
公開日2023-02-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel D-glutamate catabolic pathway in marine Proteobacteria and halophilic archaea.
Isme J, 17, 2023
4LXO
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BU of 4lxo by Molmil
Crystal structure of 9,10Fn3-elegantin chimera
分子名称: CALCIUM ION, Fibronectin
著者Chang, Y.S, Shiu, J.H, Chuang, W.J.
登録日2013-07-30
公開日2014-08-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Design, Structure Determination, and Biological Evaluation of Potent Integrin Alpha5beta1-Specific Antagonist Using the Ninth and Tenth Module of Fibronectin Type III Domain
To be Published
5TIG
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BU of 5tig by Molmil
CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY BrHPD
分子名称: (3E)-5-hydroxy-2-oxopent-3-enoic acid, 2-hydroxymuconate tautomerase
著者Zhang, Y, Li, W, Stack, T.
登録日2016-10-02
公開日2018-02-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates.
Biochemistry, 57, 2018
4OIP
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BU of 4oip by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077, ATP, and CMPcPP
分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ...
著者Zhang, Y, Ebright, R.H, Arnold, E.
登録日2014-01-20
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
7XP0
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BU of 7xp0 by Molmil
Crystal structure of PmiR from Pseudomonas aeruginosa
分子名称: Probable transcriptional regulator, SULFATE ION, ZINC ION
著者Zhang, Y.X, Liang, H.H, Gan, J.H.
登録日2022-05-02
公開日2023-04-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa.
Sci Adv, 8, 2022
7XP1
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Crystal structure of PmiR from Pseudomonas aeruginosa
分子名称: ALPHA-METHYLISOCITRIC ACID, GLYCEROL, Probable transcriptional regulator, ...
著者Zhang, Y.X, Liang, H.H, Gan, J.H.
登録日2022-05-02
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa.
Sci Adv, 8, 2022
4ES7
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BU of 4es7 by Molmil
crystal structure of protein HC from Homo sapiens at 2 angstrom
分子名称: DI(HYDROXYETHYL)ETHER, Protein AMBP
著者Zhang, Y.L, Gao, Z.Q, Wang, D.Q, Dong, Y.H.
登録日2012-04-22
公開日2013-04-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献crystal structure of protein HC from Home sapiens at 2 angstrom
To be Published
4OIR
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BU of 4oir by Molmil
Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV
分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ...
著者Zhang, Y, Ebright, R.H, Arnold, E.
登録日2014-01-20
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
7YIR
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BU of 7yir by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein from human
分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, DI(HYDROXYETHYL)ETHER
著者Zhang, Y.J, Liu, Y.R, Wu, B.
登録日2022-07-18
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
7YIS
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Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate
分子名称: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
著者Zhang, Y.J, Liu, Y.R, Wu, B.
登録日2022-07-18
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
7XS3
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AlXyn26A E243A-X3X4X
分子名称: AlXyn26A E243A-X3X4X, beta-D-xylopyranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose
著者Zhang, Y.Z, Chen, X.L, Zhao, F, Yu, C.M.
登録日2022-05-12
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel class of xylanases specifically degrade marine red algal beta 1,3/1,4-mixed-linkage xylan.
J.Biol.Chem., 299, 2023
5Y4O
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Cryo-EM structure of MscS channel, YnaI
分子名称: Low conductance mechanosensitive channel YnaI
著者Zhang, Y, Yu, J.
登録日2017-08-04
公開日2019-03-20
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A binding-block ion selective mechanism revealed by a Na/K selective channel.
Protein Cell, 9, 2018
6J1L
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BU of 6j1l by Molmil
Crystal Structure Analysis of the ROR gamma(C455E)
分子名称: 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide, Nuclear receptor ROR-gamma
著者zhang, Y, Li, C.C, wu, X.S.
登録日2018-12-28
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem., 62, 2019

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