1T0D
| Crystal Structure of 2-aminopurine labelled bacterial decoding site RNA | 分子名称: | 5'-R(*CP*AP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3', 5'-R(*GP*GP*UP*GP*GP*UP*GP*(MTU)P*AP*GP*UP*CP*GP*CP*UP*GP*G)-3' | 著者 | Shandrick, S, Zhao, Q, Han, Q, Ayida, B.K, Takahashi, M, Winters, G.C, Simonsen, K.B, Vourloumis, D, Hermann, T. | 登録日 | 2004-04-08 | 公開日 | 2004-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Monitoring molecular recognition of the ribosomal decoding site. Angew.Chem.Int.Ed.Engl., 43, 2004
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1T0E
| Crystal Structure of 2-aminopurine labelled bacterial decoding site RNA | 分子名称: | 5'-R(*CP*GP*AP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3', 5'-R(*GP*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*UP*CP*GP*G)-3', SULFATE ION | 著者 | Shandrick, S, Zhao, Q, Han, Q, Ayida, B.K, Takahashi, M, Winters, G.C, Simonsen, K.B, Vourloumis, D, Hermann, T. | 登録日 | 2004-04-08 | 公開日 | 2004-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Monitoring molecular recognition of the ribosomal decoding site. Angew.Chem.Int.Ed.Engl., 43, 2004
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3BR9
| Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor | 分子名称: | (2R)-2-({3-[5-hydroxy-2-(3-methylbutyl)-3-oxo-6-thiophen-2-yl-2,3-dihydropyridazin-4-yl]-1,1-dioxido-2H-1,2,4-benzothia diazin-7-yl}oxy)propanamide, RNA-directed RNA polymerase | 著者 | Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. | 登録日 | 2007-12-21 | 公開日 | 2008-12-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg.Med.Chem.Lett., 18, 2008
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3BSC
| Crystal Structure of HCV NS5B Polymerase with a Novel Pyridazinone Inhibitor | 分子名称: | 5-hydroxy-4-(7-methoxy-1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-2-(3-methylbutyl)-6-phenylpyridazin-3(2H)-one, RNA-directed RNA polymerase | 著者 | Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. | 登録日 | 2007-12-23 | 公開日 | 2008-12-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine. Bioorg.Med.Chem.Lett., 18, 2008
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3D5M
| Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor | 分子名称: | N-({3-[(5S)-5-tert-butyl-1-(3-chloro-4-fluorobenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-1,2-benzis othiazol-7-yl}methyl)methanesulfonamide, RNA-directed RNA polymerase | 著者 | Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. | 登録日 | 2008-05-16 | 公開日 | 2009-05-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
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1W7L
| Crystal structure of human kynurenine aminotransferase I | 分子名称: | KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PYRIDOXAL-5'-PHOSPHATE | 著者 | Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. | 登録日 | 2004-09-06 | 公開日 | 2004-09-08 | 最終更新日 | 2015-12-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
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1W7N
| Crystal structure of human kynurenine aminotransferase I in PMP form | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, KYNURENINE--OXOGLUTARATE TRANSAMINASE I | 著者 | Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. | 登録日 | 2004-09-06 | 公開日 | 2004-09-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
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1W7M
| Crystal structure of human kynurenine aminotransferase I in complex with L-Phe | 分子名称: | KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PHENYLALANINE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. | 登録日 | 2004-09-06 | 公開日 | 2004-09-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
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8JI8
| Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ... | 著者 | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | 登録日 | 2023-05-26 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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8JIB
| Crystal Structure of Prophenoloxidase PPO6 from Aedes aegypti | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, TK receptor | 著者 | Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q. | 登録日 | 2023-05-26 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Mosquitoes have evolved two types of prophenoloxidases To Be Published
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3R4L
| Human very long half life Plasminogen Activator Inhibitor type-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J. | 登録日 | 2011-03-17 | 公開日 | 2011-11-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure. Int.J.Mol.Med., 29, 2012
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1PG8
| Crystal Structure of L-methionine alpha-, gamma-lyase | 分子名称: | DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Allen, T.W, Sridhar, V, Prasad, G.S, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S. | 登録日 | 2003-05-28 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | To Be Published
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1PFF
| Crystal Structure of Homocysteine alpha-, gamma-lyase at 1.8 Angstroms | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, methionine gamma-lyase | 著者 | Allen, T.W, Sridhar, V, Prasad, S.G, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S. | 登録日 | 2003-05-26 | 公開日 | 2004-08-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 |
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6JRL
| Crystal structure of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase | 分子名称: | 3,4-dihydroxyphenylacetaldehyde synthase | 著者 | Wei, S, Vavrick, C.J, Guan, H, Liao, C, Robinson, H, Liang, J, Wang, D, Han, Q, Li, J. | 登録日 | 2019-04-04 | 公開日 | 2019-04-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the bifunctional mechanism of Drosophila alpha methyldopa-resistant protein/3,4-dihydroxyphenylacetaldehyde synthase To Be Published
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3PDX
| Crystal structural of mouse tyrosine aminotransferase | 分子名称: | Tyrosine aminotransferase | 著者 | Mehere, P.V, Han, Q, Lemkul, J.A, Robinson, H, Bevan, D.R, Li, J. | 登録日 | 2010-10-25 | 公開日 | 2010-11-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. Protein Cell, 1, 2010
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3CVK
| Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor | 分子名称: | N-{3-[1-(3,3-Dimethyl-butyl)-4-hydroxy-2-oxo-1,2,4a,5,6,7-hexahydro-pyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxo-1,2-dihydro -1lambda6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide, RNA-directed RNA polymerase | 著者 | Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. | 登録日 | 2008-04-18 | 公開日 | 2009-04-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
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