Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 610 件
4G0W
DownloadVisualize
BU of 4g0w by Molmil
Human topoisomerase iibeta in complex with DNA and ametantrone
分子名称: 1,4-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
著者Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
登録日2012-07-10
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.696 Å)
主引用文献On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
3B6H
DownloadVisualize
BU of 3b6h by Molmil
Crystal structure of human prostacyclin synthase in complex with inhibitor minoxidil
分子名称: 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE, PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, ...
著者Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L.
登録日2007-10-29
公開日2007-11-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
3B99
DownloadVisualize
BU of 3b99 by Molmil
Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) in complex with substrate analog U51605
分子名称: (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}hept-5-enoic acid, PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase
著者Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L.
登録日2007-11-03
公開日2007-11-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
4GIL
DownloadVisualize
BU of 4gil by Molmil
Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear Pseudouridine 5'-Phosphate Adduct
分子名称: MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, pseudouridine 5'-phosphate, ...
著者Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E.
登録日2012-08-08
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.539 Å)
主引用文献Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4G0U
DownloadVisualize
BU of 4g0u by Molmil
Human topoisomerase IIbeta in complex with DNA and amsacrine
分子名称: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
著者Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
登録日2012-07-10
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
1O9K
DownloadVisualize
BU of 1o9k by Molmil
Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
分子名称: RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
著者Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J.
登録日2002-12-16
公開日2003-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
2IAG
DownloadVisualize
BU of 2iag by Molmil
Crystal structure of human prostacyclin synthase
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Prostacyclin synthase, SODIUM ION
著者Chiang, C.-W, Yeh, H.-C, Wang, L.-H, Chan, N.-L.
登録日2006-09-08
公開日2006-10-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of the Human Prostacyclin Synthase
J.Mol.Biol., 364, 2006
3B98
DownloadVisualize
BU of 3b98 by Molmil
Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1)
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase
著者Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L.
登録日2007-11-03
公開日2007-11-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change
J.Biol.Chem., 283, 2008
4C46
DownloadVisualize
BU of 4c46 by Molmil
ANDREI-N-LVPAS fused to GCN4 adaptors
分子名称: BROMIDE ION, GENERAL CONTROL PROTEIN GCN4
著者Albrecht, R, Alva, V, Ammelburg, M, Baer, K, Basina, E, Boichenko, I, Bonhoeffer, F, Braun, V, Chaubey, M, Chauhan, N, Chellamuthu, V.R, Coles, M, Deiss, S, Ewers, C.P, Forouzan, D, Fuchs, A, Groemping, Y, Hartmann, M.D, Hernandez Alvarez, B, Jeganantham, A, Kalev, I, Koenninger, U, Koiwai, K, Kopec, K.O, Korycinski, M, Laudenbach, B, Lehmann, K, Leo, J.C, Linke, D, Marialke, J, Martin, J, Mechelke, M, Michalik, M, Noll, A, Patzer, S.I, Scharfenberg, F, Schueckel, M, Shahid, S.A, Sulz, E, Ursinus, A, Wuertenberger, S, Zhu, H.
登録日2013-08-30
公開日2013-09-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Your Personalized Protein Structure: Andrei N. Lupas Fused to GCN4 Adaptors.
J.Struct.Biol., 186, 2014
1MO4
DownloadVisualize
BU of 1mo4 by Molmil
RECA-ATP-GAMMA-S COMPLEX
分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, RecA
著者Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC)
登録日2002-09-07
公開日2003-02-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition
Proteins, 50, 2003
2ASS
DownloadVisualize
BU of 2ass by Molmil
Crystal structure of the Skp1-Skp2-Cks1 complex
分子名称: BENZAMIDINE, Cyclin-dependent kinases regulatory subunit 1, PHOSPHATE ION, ...
著者Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P.
登録日2005-08-24
公開日2005-10-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
1MO5
DownloadVisualize
BU of 1mo5 by Molmil
RECA-ATP-GAMMA-S-MG COMPLEX
分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, RecA
著者Datta, S, Ganesh, N, Chandra, N.R, TB Structural Genomics Consortium (TBSGC)
登録日2002-09-07
公開日2003-02-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition
Proteins, 50, 2003
4LM5
DownloadVisualize
BU of 4lm5 by Molmil
Crystal structure of Pim1 in complex with 2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol (resulting from displacement of SKF86002)
分子名称: 2-{4-[(3-aminopropyl)amino]quinazolin-2-yl}phenol, GLYCEROL, Serine/threonine-protein kinase pim-1
著者Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
登録日2013-07-10
公開日2014-02-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
7DO1
DownloadVisualize
BU of 7do1 by Molmil
Solution structure of a heteromolecular telomeric (3+1) G-quadruplex containing right loop progression
分子名称: DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*G)-3')
著者Fu, W.Q, Jing, H.T, Zhang, N.
登録日2020-12-11
公開日2021-09-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two coexisting pseudo-mirror heteromolecular telomeric G-quadruplexes in opposite loop progressions differentially recognized by a low equivalent of Thioflavin T.
Nucleic Acids Res., 49, 2021
3ATV
DownloadVisualize
BU of 3atv by Molmil
Crystal structure of human Hsp70 NBD in the ADP-bound and Mg ion-free state
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Heat shock 70 kDa protein 1A/1B, ...
著者Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-13
公開日2011-12-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Biochemical and structural studies on the high affinity of Hsp70 for ADP.
Protein Sci., 20, 2011
3ATU
DownloadVisualize
BU of 3atu by Molmil
Crystal structure of human Hsp70 NBD in the ADP- and Mg ion-bound state
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, ...
著者Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-13
公開日2011-12-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Biochemical and structural studies on the high affinity of Hsp70 for ADP.
Protein Sci., 20, 2011
4GIM
DownloadVisualize
BU of 4gim by Molmil
Crystal Structure of Pseudouridine Monophosphate Glycosidase Complexed with Pseudouridine 5'-phosphate
分子名称: MANGANESE (II) ION, PSEUDOURIDINE-5'-MONOPHOSPHATE, Pseudouridine-5'-phosphate glycosidase
著者Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E.
登録日2012-08-08
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4G0V
DownloadVisualize
BU of 4g0v by Molmil
Human topoisomerase iibeta in complex with DNA and mitoxantrone
分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
著者Wu, C.C, Li, T.K, Li, Y.C, Chan, N.L.
登録日2012-07-10
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs
Nucleic Acids Res., 41, 2013
1WP5
DownloadVisualize
BU of 1wp5 by Molmil
Crystal structure of the C-terminal domain of DNA topoisomerase IV
分子名称: topoisomerase IV
著者Hsieh, T.-J, Farh, L, Huang, W.M, Chan, N.-L.
登録日2004-08-30
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure of the topoisomerase IV C-terminal domain: a broken beta-propeller implies a role as geometry facilitator in catalysis
J.Biol.Chem., 279, 2004
4LMU
DownloadVisualize
BU of 4lmu by Molmil
Crystal structure of Pim1 in complex with the inhibitor Quercetin (resulting from displacement of SKF86002)
分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, GLYCEROL, Serine/threonine-protein kinase pim-1
著者Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
登録日2013-07-11
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
4GIJ
DownloadVisualize
BU of 4gij by Molmil
Crystal Structure of Pseudouridine Monophosphate Glycosidase Complexed with Sulfate
分子名称: MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, SULFATE ION
著者Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E.
登録日2012-08-08
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.941 Å)
主引用文献Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
4GIK
DownloadVisualize
BU of 4gik by Molmil
Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear R5P Adduct
分子名称: MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, RIBOSE-5-PHOSPHATE
著者Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E.
登録日2012-08-08
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
1RHB
DownloadVisualize
BU of 1rhb by Molmil
WATER DEPENDENT DOMAIN MOTION AND FLEXIBILITY IN RIBONUCLEASE A AND THE INVARIANT FEATURES IN ITS HYDRATION SHELL. AN X-RAY STUDY OF TWO LOW HUMIDITY CRYSTAL FORMS OF THE ENZYME
分子名称: RIBONUCLEASE A
著者Radha Kishan, K.V, Chandra, N.R, Sudarsanakumar, C, Suguna, K, Vijayan, M.
登録日1994-11-13
公開日1995-02-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Water-dependent domain motion and flexibility in ribonuclease A and the invariant features in its hydration shell. An X-ray study of two low-humidity crystal forms of the enzyme.
Acta Crystallogr.,Sect.D, 51, 1995
2ZRB
DownloadVisualize
BU of 2zrb by Molmil
MsRecA Q196E Form II'
分子名称: PHOSPHATE ION, Protein recA
著者Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M.
登録日2008-08-27
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes
Acta Crystallogr.,Sect.D, 64, 2008
2ZRJ
DownloadVisualize
BU of 2zrj by Molmil
MsRecA Q196A ATPgS form IV
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CHLORIDE ION, GLYCEROL, ...
著者Prabu, J.R, Manjunath, G.P, Chandra, N.R, Muniyappa, K, Vijayan, M.
登録日2008-08-27
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes
Acta Crystallogr.,Sect.D, 64, 2008

221371

件を2024-06-19に公開中

PDB statisticsPDBj update infoContact PDBjnumon