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PDB: 738 results

7BVF
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BU of 7bvf by Molmil
Cryo-EM structure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol
Descriptor: CALCIUM ION, CARDIOLIPIN, Ethambutol, ...
Authors:Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
Deposit date:2020-04-10
Release date:2020-04-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVE
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BU of 7bve by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol
Descriptor: CALCIUM ION, Ethambutol, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, ...
Authors:Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
Deposit date:2020-04-10
Release date:2020-04-29
Last modified:2020-07-01
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVG
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BU of 7bvg by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose.
Descriptor: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ...
Authors:Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
Deposit date:2020-04-10
Release date:2020-04-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
8B35
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BU of 8b35 by Molmil
Chalcone synthase from Hordeum vulgare complexed with CoA and naringenin
Descriptor: COENZYME A, Chalcone synthase 2, NARINGENIN
Authors:Zhang, L, Groves, M.R.
Deposit date:2022-09-15
Release date:2023-09-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids.
J.Agric.Food Chem., 72, 2024
8B32
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BU of 8b32 by Molmil
Chalcone synthase from Hordeum vulgare complexed with CoA
Descriptor: COENZYME A, Chalcone synthase 2
Authors:Zhang, L, Groves, M.R.
Deposit date:2022-09-15
Release date:2023-09-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids.
J.Agric.Food Chem., 72, 2024
8B3C
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BU of 8b3c by Molmil
Chalcone synthase from Hordeum vulgare complexed with CoA and eriodictyol
Descriptor: (2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, COENZYME A, Chalcone synthase 2
Authors:Zhang, L, Groves, M.R.
Deposit date:2022-09-16
Release date:2023-09-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids.
J.Agric.Food Chem., 72, 2024
8AHX
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BU of 8ahx by Molmil
Cryo-EM structure of the nitrogen-fixation associated NADH:ferredoxin oxidoreductase RNF from Azotobacter vinelandii
Descriptor: DODECYL-BETA-D-MALTOSIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Zhang, L, Einsle, O.
Deposit date:2022-07-24
Release date:2023-11-01
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Architecture of the RNF1 complex that drives biological nitrogen fixation.
Nat.Chem.Biol., 2024
7ZNQ
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ABC transporter complex NosDFYL in GDN
Descriptor: COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ...
Authors:Zhang, L, Mueller, C, Zipfel, S, Chami, M, Einsle, O.
Deposit date:2022-04-21
Release date:2022-08-03
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
1HGU
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BU of 1hgu by Molmil
HUMAN GROWTH HORMONE
Descriptor: HUMAN GROWTH HORMONE
Authors:Chantalat, L, Jones, N, Korber, F, Navaza, J, Pavlovsky, A.G.
Deposit date:1995-05-11
Release date:1995-12-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:THE CRYSTAL-STRUCTURE OF WILD-TYPE GROWTH-HORMONE AT 2.5 ANGSTROM RESOLUTION.
Protein Pept.Lett., 2, 1995
8C9T
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BU of 8c9t by Molmil
Catechol O-methyltransferase from Streptomyces avermitilis
Descriptor: GLYCEROL, Putative O-methyltransferase
Authors:Zhang, L, Groves, M.R.
Deposit date:2023-01-23
Release date:2023-04-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Characterization and Extended Substrate Scope Analysis of Two Mg 2+ -Dependent O-Methyltransferases from Bacteria.
Chembiochem, 24, 2023
8C9V
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BU of 8c9v by Molmil
O-methyltransferase from Desulfuromonas acetoxidans
Descriptor: MAGNESIUM ION, O-methyltransferase, family 3
Authors:Zhang, L, Groves, M.R.
Deposit date:2023-01-23
Release date:2023-04-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Characterization and Extended Substrate Scope Analysis of Two Mg 2+ -Dependent O-Methyltransferases from Bacteria.
Chembiochem, 24, 2023
8C9S
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BU of 8c9s by Molmil
Catechol O-methyltransferase from Streptomyces avermitilis in complex with SAH
Descriptor: MAGNESIUM ION, Putative O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhang, L, Groves, M.R.
Deposit date:2023-01-23
Release date:2023-04-05
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Characterization and Extended Substrate Scope Analysis of Two Mg 2+ -Dependent O-Methyltransferases from Bacteria.
Chembiochem, 24, 2023
1HQ3
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BU of 1hq3 by Molmil
CRYSTAL STRUCTURE OF THE HISTONE-CORE-OCTAMER IN KCL/PHOSPHATE
Descriptor: CHLORIDE ION, HISTONE H2A-IV, HISTONE H2B, ...
Authors:Chantalat, L, Nicholson, J.M, Lambert, S.J, Reid, A.J, Donovan, M.J, Reynolds, C.D, Wood, C.M, Baldwin, J.P.
Deposit date:2000-12-14
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the histone-core octamer in KCl/phosphate crystals at 2.15 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
5N19
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BU of 5n19 by Molmil
Structure of SARS coronavirus main protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide
Descriptor: (S)-N-benzyl-3-((S)-2-cinnamamido-3-phenylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide, DIMETHYL SULFOXIDE, SARS coronavirus main protease
Authors:Zhang, L, Ma, Q, Hilgenfeld, R.
Deposit date:2017-02-05
Release date:2018-02-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
5N5O
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BU of 5n5o by Molmil
Structure of SARS coronavirus main protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-cyclopropylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide (Cinnamoyl-cyclopropylalanine-GlnLactam-CO-CO-NH-benzyl)
Descriptor: (2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanoyl]amino]-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-~{N}-(phenylmethyl)butanamide, Replicase polyprotein 1ab
Authors:Zhang, L, Hilgenfeld, R.
Deposit date:2017-02-14
Release date:2018-03-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
5NH0
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BU of 5nh0 by Molmil
Structure of human coronavirus NL63 main protease in complex with the alpha-ketoamide tert-Butyl ((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)b- utan-2-yl)carbamate (tert-butyl -GlnLactam-CO-CO-NH-benzyl)
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Zhang, L, Hilgenfeld, R.
Deposit date:2017-03-21
Release date:2018-05-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
5MGY
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BU of 5mgy by Molmil
Crystal structure of Pseudomonas stutzeri flavinyl transferase ApbE, apo form
Descriptor: FAD:protein FMN transferase, MAGNESIUM ION
Authors:Zhang, L, Trncik, C, Andrade, S.L.A, Einsle, O.
Deposit date:2016-11-22
Release date:2016-12-14
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The flavinyl transferase ApbE of Pseudomonas stutzeri matures the NosR protein required for nitrous oxide reduction.
Biochim. Biophys. Acta, 1858, 2016
6RL0
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BU of 6rl0 by Molmil
Recombinant Pseudomonas stutzeri nitrous oxide reductase, form I
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Zhang, L, Wuest, A, Prasser, B, Mueller, C, Einsle, O.
Deposit date:2019-04-30
Release date:2019-06-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Functional assembly of nitrous oxide reductase provides insights into copper site maturation.
Proc.Natl.Acad.Sci.USA, 116, 2019
7FAE
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BU of 7fae by Molmil
S protein of SARS-CoV-2 in complex bound with P36-5D2(state2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P36-5D2 heavy chain, ...
Authors:Zhang, L, Wang, X, Shan, S, Zhang, S.
Deposit date:2021-07-06
Release date:2021-12-22
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants.
Front Immunol, 12, 2021
7FAF
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BU of 7faf by Molmil
S protein of SARS-CoV-2 in complex bound with P36-5D2 (state1)
Descriptor: P36-5D2 heavy chain, P36-5D2 light chain, Spike glycoprotein
Authors:Zhang, L, Wang, X, Zhang, S, Shan, S.
Deposit date:2021-07-06
Release date:2021-12-22
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants.
Front Immunol, 12, 2021
6FX0
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BU of 6fx0 by Molmil
Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne
Descriptor: 6-[3-(1-adamantyl)-4-oxidanyl-phenyl]naphthalene-2-carboxylic acid, Retinoic acid receptor gamma, TETRAETHYLENE GLYCOL
Authors:Chantalat, L, Thoreau, E.
Deposit date:2018-03-08
Release date:2018-05-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the treatment of acne.
Bioorg. Med. Chem. Lett., 28, 2018
5H9G
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BU of 5h9g by Molmil
apo-ACP from Helicobacter pylori
Descriptor: Acyl carrier protein
Authors:Zhang, L, Zhang, L, Shen, X, Jiang, H.
Deposit date:2015-12-28
Release date:2016-12-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:apo-ACP from Helicobacter pylori
To Be Published
5H9H
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BU of 5h9h by Molmil
holo acyl carrier protein (holo-ACP) from Helicobacter pylori
Descriptor: Acyl carrier protein
Authors:Zhang, L, Zhang, L, Shen, X, Jiang, H.
Deposit date:2015-12-28
Release date:2016-12-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:holo acyl carrier protein (holo-ACP) from Helicobacter pylori
To Be Published
3CF8
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BU of 3cf8 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with quercetin
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, BENZAMIDINE, ...
Authors:Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H.
Deposit date:2008-03-03
Release date:2008-12-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008
3CF9
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Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin
Descriptor: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, BENZAMIDINE, ...
Authors:Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H.
Deposit date:2008-03-03
Release date:2008-12-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17, 2008

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