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PDB: 351 results

8EKL
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BU of 8ekl by Molmil
Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 1
Descriptor: ADP-ribosyltransferase binding component, CALCIUM ION
Authors:Abeyawardhane, D.L, Pozharski, E.
Deposit date:2022-09-21
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin
To Be Published
8UK6
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BU of 8uk6 by Molmil
Candida albicans glutaminyl tRNA synthetase (GLN4) in complex with N-pyrimidinyl-beta-thiophenylacrylamide
Descriptor: (2E)-N-(pyrimidin-2-yl)-3-(thiophen-2-yl)prop-2-enamide, ZINC ION, glutamine--tRNA ligase
Authors:Sychantha, D, Wright, G.D.
Deposit date:2023-10-12
Release date:2024-03-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-beta-thiophenylacrylamides exerts highly selective antifungal activity.
Cell Chem Biol, 31, 2024
7OCC
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BU of 7occ by Molmil
NTD of resting state GluA1/A2 heterotertramer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 1, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCA
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BU of 7oca by Molmil
Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
5VZ3
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BU of 5vz3 by Molmil
Growth Factor Crystal Structure at 1.97 Angstrom Resolution
Descriptor: Growth/differentiation factor 15
Authors:Lakshminarasimhan, D, White, A, Suto, R.K.
Deposit date:2017-05-26
Release date:2017-09-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
Nature, 550, 2017
5VZ4
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BU of 5vz4 by Molmil
Receptor-growth factor crystal structure at 2.20 Angstrom resolution
Descriptor: 1,2-ETHANEDIOL, BROMIDE ION, GDNF family receptor alpha-like, ...
Authors:Lakshminarasimhan, D, White, A, Suto, R.K.
Deposit date:2017-05-26
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
Nature, 550, 2017
5W4Z
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BU of 5w4z by Molmil
Crystal Structure of Riboflavin Lyase (RcaE) with modified FMN and substrate Riboflavin
Descriptor: 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-3-O-phosphono-D-ribitol, RIBOFLAVIN, Riboflavin Lyase
Authors:Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P.
Deposit date:2017-06-13
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical
To be Published
3NS8
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BU of 3ns8 by Molmil
Crystal structure of an open conformation of Lys48-linked diubiquitin at pH 7.5
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ubiquitin
Authors:Zhang, D, LaRonde-LeBlanc, N, Fushman, D.
Deposit date:2010-07-01
Release date:2011-07-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.707 Å)
Cite:Structural and biochemical studies of the open state of Lys48-linked diubiquitin.
Biochim.Biophys.Acta, 1823, 2012
2JY5
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BU of 2jy5 by Molmil
NMR structure of Ubiquilin 1 UBA domain
Descriptor: Ubiquilin-1
Authors:Zhang, D, Raasi, S, Fushman, D.
Deposit date:2007-12-06
Release date:2008-03-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008
2JY6
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BU of 2jy6 by Molmil
Solution structure of the complex of ubiquitin and ubiquilin 1 UBA domain
Descriptor: Ubiquilin-1, Ubiquitin protein
Authors:Zhang, D, Raasi, S, Fushman, D.
Deposit date:2007-12-06
Release date:2008-03-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008
5V8E
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BU of 5v8e by Molmil
Structure of Bacillus cereus PatB1
Descriptor: Bacillus cereus PatB1, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Sychantha, D, Little, D.J, Chapman, R.N, Boons, G.J, Robinson, H, Howell, P.L, Clarke, A.J.
Deposit date:2017-03-21
Release date:2017-10-18
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.
Nat. Chem. Biol., 14, 2018
7OCD
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BU of 7ocd by Molmil
Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCE
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BU of 7oce by Molmil
Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, CHOLESTEROL, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCF
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BU of 7ocf by Molmil
Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLOTHIAZIDE, GLUTAMIC ACID, ...
Authors:Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
Deposit date:2021-04-26
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
2MRO
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BU of 2mro by Molmil
Structure of the complex of ubiquitin and the UBA domain from DNA-damage-inducible 1 protein (Ddi1)
Descriptor: DNA damage-inducible protein 1, Polyubiquitin-B
Authors:Zhang, D, Fushman, D.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
2MR9
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BU of 2mr9 by Molmil
NMR structure of UBA domain of DNA-damage-inducible 1 protein (Ddi1)
Descriptor: DNA damage-inducible protein 1
Authors:Zhang, D, Fushman, D.
Deposit date:2014-07-02
Release date:2015-02-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
5W4Y
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BU of 5w4y by Molmil
Crystal Structure of Riboflavin Lyase (RcaE) with cofactor FMN
Descriptor: FLAVIN MONONUCLEOTIDE, Riboflavin Lyase
Authors:Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P.
Deposit date:2017-06-13
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical
To be Published
5W48
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BU of 5w48 by Molmil
Crystal Structure of Riboflavin Lyase (RcaE)
Descriptor: Riboflavin Lyase, SULFATE ION
Authors:Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P.
Deposit date:2017-06-09
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical
To be Published
1MVU
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BU of 1mvu by Molmil
SINGLE CHAIN FV OF C219 HEAVY CHAIN V101L MUTANT IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE
Descriptor: Ig VDJ-region (HEAVY CHAIN), Ig kappa-chain VJ-region (Light chain), P-GLYCOPROTEIN, ...
Authors:Chan, D.C.M, Kuntz, D.A, Rose, D.R.
Deposit date:2002-09-26
Release date:2003-10-07
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Single Chain C219 V(101H)L Mutant Antibody Complexed with a Helical Peptide
To be Published
4YH4
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BU of 4yh4 by Molmil
Crystal structure of human BRD4(1) in complex with 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19d)
Descriptor: 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one, Bromodomain-containing protein 4, GLYCEROL, ...
Authors:Lakshminarasimhan, D, White, A, Suto, R.K.
Deposit date:2015-02-26
Release date:2016-01-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
Bioorg.Med.Chem.Lett., 25, 2015
6BT4
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BU of 6bt4 by Molmil
Crystal structure of the SLH domain of Sap from Bacillus anthracis in complex with a pyruvylated SCWP unit
Descriptor: 2-(acetylamino)-4-O-{2-(acetylamino)-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranose, S-layer protein sap, SULFATE ION
Authors:Sychantha, D, Chapman, R.N, Bamford, N.C, Boons, G.J, Howell, P.L, Clarke, A.J.
Deposit date:2017-12-05
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.
Biochemistry, 57, 2018
1H6H
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BU of 1h6h by Molmil
Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate
Descriptor: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, GLYCEROL, NEUTROPHIL CYTOSOL FACTOR 4
Authors:Karathanassis, D, Bravo, J, Pacold, M, Perisic, O, Williams, R.L.
Deposit date:2001-06-15
Release date:2001-11-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate
Mol.Cell, 8, 2001
6ASL
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BU of 6asl by Molmil
Crystal Structure of Flavin monooxygenase CmoJ (earlier YtnJ) bound with FMN
Descriptor: FLAVIN MONONUCLEOTIDE, LUMIFLAVIN, Putative monooxygenase MoxC
Authors:Bhandari, D.M, Zhao, B, Li, P, Begley, T.P.
Deposit date:2017-08-24
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Flavin mediated Pummerer type rearrangement in cysteine salvage pathway
To Be Published
6ASK
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BU of 6ask by Molmil
Crystal Structure of apo Flavin monooxygenase CmoJ (earlier YtnJ)
Descriptor: Putative monooxygenase MoxC
Authors:Bhandari, D.M, Zhao, B, Li, P, Begley, T.P.
Deposit date:2017-08-24
Release date:2018-08-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Flavin mediated Pummerer type rearrangement in cysteine salvage pathway
To Be Published
1AV1
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BU of 1av1 by Molmil
CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I
Descriptor: APOLIPOPROTEIN A-I
Authors:Borhani, D.W, Rogers, D.P, Engler, J.A, Brouillette, C.G.
Deposit date:1997-09-23
Release date:1998-02-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation.
Proc.Natl.Acad.Sci.USA, 94, 1997

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