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PDB: 351 件

8EKL
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Clostridioides difficile binary toxin translocase CDTb wild-type after calcium depletion from receptor binding domain 1 (RBD1) - Class 1
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Abeyawardhane, D.L, Pozharski, E.
登録日2022-09-21
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Calcium-mediated Pore Formation of Clostridioides difficile Binary Toxin
To Be Published
8UK6
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BU of 8uk6 by Molmil
Candida albicans glutaminyl tRNA synthetase (GLN4) in complex with N-pyrimidinyl-beta-thiophenylacrylamide
分子名称: (2E)-N-(pyrimidin-2-yl)-3-(thiophen-2-yl)prop-2-enamide, ZINC ION, glutamine--tRNA ligase
著者Sychantha, D, Wright, G.D.
登録日2023-10-12
公開日2024-03-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-beta-thiophenylacrylamides exerts highly selective antifungal activity.
Cell Chem Biol, 31, 2024
7OCC
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BU of 7occ by Molmil
NTD of resting state GluA1/A2 heterotertramer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 1, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCA
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BU of 7oca by Molmil
Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
5VZ3
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BU of 5vz3 by Molmil
Growth Factor Crystal Structure at 1.97 Angstrom Resolution
分子名称: Growth/differentiation factor 15
著者Lakshminarasimhan, D, White, A, Suto, R.K.
登録日2017-05-26
公開日2017-09-27
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
Nature, 550, 2017
5VZ4
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BU of 5vz4 by Molmil
Receptor-growth factor crystal structure at 2.20 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, GDNF family receptor alpha-like, ...
著者Lakshminarasimhan, D, White, A, Suto, R.K.
登録日2017-05-26
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.
Nature, 550, 2017
5W4Z
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BU of 5w4z by Molmil
Crystal Structure of Riboflavin Lyase (RcaE) with modified FMN and substrate Riboflavin
分子名称: 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-3-O-phosphono-D-ribitol, RIBOFLAVIN, Riboflavin Lyase
著者Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P.
登録日2017-06-13
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical
To be Published
3NS8
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BU of 3ns8 by Molmil
Crystal structure of an open conformation of Lys48-linked diubiquitin at pH 7.5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ubiquitin
著者Zhang, D, LaRonde-LeBlanc, N, Fushman, D.
登録日2010-07-01
公開日2011-07-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Structural and biochemical studies of the open state of Lys48-linked diubiquitin.
Biochim.Biophys.Acta, 1823, 2012
2JY5
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BU of 2jy5 by Molmil
NMR structure of Ubiquilin 1 UBA domain
分子名称: Ubiquilin-1
著者Zhang, D, Raasi, S, Fushman, D.
登録日2007-12-06
公開日2008-03-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008
2JY6
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BU of 2jy6 by Molmil
Solution structure of the complex of ubiquitin and ubiquilin 1 UBA domain
分子名称: Ubiquilin-1, Ubiquitin protein
著者Zhang, D, Raasi, S, Fushman, D.
登録日2007-12-06
公開日2008-03-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains
J.Mol.Biol., 377, 2008
5V8E
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BU of 5v8e by Molmil
Structure of Bacillus cereus PatB1
分子名称: Bacillus cereus PatB1, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Sychantha, D, Little, D.J, Chapman, R.N, Boons, G.J, Robinson, H, Howell, P.L, Clarke, A.J.
登録日2017-03-21
公開日2017-10-18
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.
Nat. Chem. Biol., 14, 2018
7OCD
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BU of 7ocd by Molmil
Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCE
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BU of 7oce by Molmil
Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, CHOLESTEROL, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
7OCF
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BU of 7ocf by Molmil
Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLOTHIAZIDE, GLUTAMIC ACID, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
2MRO
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BU of 2mro by Molmil
Structure of the complex of ubiquitin and the UBA domain from DNA-damage-inducible 1 protein (Ddi1)
分子名称: DNA damage-inducible protein 1, Polyubiquitin-B
著者Zhang, D, Fushman, D.
登録日2014-07-14
公開日2015-02-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
2MR9
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BU of 2mr9 by Molmil
NMR structure of UBA domain of DNA-damage-inducible 1 protein (Ddi1)
分子名称: DNA damage-inducible protein 1
著者Zhang, D, Fushman, D.
登録日2014-07-02
公開日2015-02-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
5W4Y
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BU of 5w4y by Molmil
Crystal Structure of Riboflavin Lyase (RcaE) with cofactor FMN
分子名称: FLAVIN MONONUCLEOTIDE, Riboflavin Lyase
著者Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P.
登録日2017-06-13
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical
To be Published
5W48
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BU of 5w48 by Molmil
Crystal Structure of Riboflavin Lyase (RcaE)
分子名称: Riboflavin Lyase, SULFATE ION
著者Bhandari, D.M, Chakrabarty, Y, Zhao, B, Wood, J, Li, P, Begley, T.P.
登録日2017-06-09
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cannibalism Among the Flavins: a Novel C-N Bond Cleavage in Riboflavin Catabolism Mediated by Flavin-Generated Superoxide Radical
To be Published
1MVU
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BU of 1mvu by Molmil
SINGLE CHAIN FV OF C219 HEAVY CHAIN V101L MUTANT IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE
分子名称: Ig VDJ-region (HEAVY CHAIN), Ig kappa-chain VJ-region (Light chain), P-GLYCOPROTEIN, ...
著者Chan, D.C.M, Kuntz, D.A, Rose, D.R.
登録日2002-09-26
公開日2003-10-07
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Single Chain C219 V(101H)L Mutant Antibody Complexed with a Helical Peptide
To be Published
4YH4
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BU of 4yh4 by Molmil
Crystal structure of human BRD4(1) in complex with 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19d)
分子名称: 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one, Bromodomain-containing protein 4, GLYCEROL, ...
著者Lakshminarasimhan, D, White, A, Suto, R.K.
登録日2015-02-26
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
Bioorg.Med.Chem.Lett., 25, 2015
6BT4
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BU of 6bt4 by Molmil
Crystal structure of the SLH domain of Sap from Bacillus anthracis in complex with a pyruvylated SCWP unit
分子名称: 2-(acetylamino)-4-O-{2-(acetylamino)-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranose, S-layer protein sap, SULFATE ION
著者Sychantha, D, Chapman, R.N, Bamford, N.C, Boons, G.J, Howell, P.L, Clarke, A.J.
登録日2017-12-05
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.
Biochemistry, 57, 2018
1H6H
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BU of 1h6h by Molmil
Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate
分子名称: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, GLYCEROL, NEUTROPHIL CYTOSOL FACTOR 4
著者Karathanassis, D, Bravo, J, Pacold, M, Perisic, O, Williams, R.L.
登録日2001-06-15
公開日2001-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate
Mol.Cell, 8, 2001
6ASL
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BU of 6asl by Molmil
Crystal Structure of Flavin monooxygenase CmoJ (earlier YtnJ) bound with FMN
分子名称: FLAVIN MONONUCLEOTIDE, LUMIFLAVIN, Putative monooxygenase MoxC
著者Bhandari, D.M, Zhao, B, Li, P, Begley, T.P.
登録日2017-08-24
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Flavin mediated Pummerer type rearrangement in cysteine salvage pathway
To Be Published
6ASK
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BU of 6ask by Molmil
Crystal Structure of apo Flavin monooxygenase CmoJ (earlier YtnJ)
分子名称: Putative monooxygenase MoxC
著者Bhandari, D.M, Zhao, B, Li, P, Begley, T.P.
登録日2017-08-24
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Flavin mediated Pummerer type rearrangement in cysteine salvage pathway
To Be Published
1AV1
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BU of 1av1 by Molmil
CRYSTAL STRUCTURE OF HUMAN APOLIPOPROTEIN A-I
分子名称: APOLIPOPROTEIN A-I
著者Borhani, D.W, Rogers, D.P, Engler, J.A, Brouillette, C.G.
登録日1997-09-23
公開日1998-02-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation.
Proc.Natl.Acad.Sci.USA, 94, 1997

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