6S7D
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![BU of 6s7d by Molmil](/molmil-images/mine/6s7d) | Self-complementary duplex DNA containing an internucleoside phosphoroselenolate | Descriptor: | BARIUM ION, CHLORIDE ION, DNA (5'-D(*GP*(XCI)P*CP*CP*CP*GP*GP*GP*AP*C)-3'), ... | Authors: | Conlon, P.F, Steinhogl, J, Vyle, J.S, Hall, J.P. | Deposit date: | 2019-07-04 | Release date: | 2019-11-06 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography. Chem Sci, 10, 2019
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4YMC
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![BU of 4ymc by Molmil](/molmil-images/mine/4ymc) | Lambda-[Ru(TAP)2(dppz)]2+ bound to d(CCGGATCCGG)2 | Descriptor: | BARIUM ION, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*GP*AP*TP*CP*CP*GP*G)-3'), ... | Authors: | Gurung, S.P, Hall, J.P, Cardin, C.J. | Deposit date: | 2015-03-06 | Release date: | 2016-03-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Reversal of a single base pair step controls guanine photo-oxidation by an intercalating Ru(II) dipyridophenazine complex. To Be Published
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8OE3
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![BU of 8oe3 by Molmil](/molmil-images/mine/8oe3) | |
8OEB
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![BU of 8oeb by Molmil](/molmil-images/mine/8oeb) | |
8OE8
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![BU of 8oe8 by Molmil](/molmil-images/mine/8oe8) | |
8OE7
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![BU of 8oe7 by Molmil](/molmil-images/mine/8oe7) | |
8OEX
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![BU of 8oex by Molmil](/molmil-images/mine/8oex) | |
8OEZ
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![BU of 8oez by Molmil](/molmil-images/mine/8oez) | |
8OEA
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![BU of 8oea by Molmil](/molmil-images/mine/8oea) | |
8OE9
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![BU of 8oe9 by Molmil](/molmil-images/mine/8oe9) | |
8OEC
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![BU of 8oec by Molmil](/molmil-images/mine/8oec) | |
5LS8
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![BU of 5ls8 by Molmil](/molmil-images/mine/5ls8) | Light-activated ruthenium complex bound to a DNA quadruplex | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*A)-3'), POTASSIUM ION, delta-[Ru(tap2-dppz-CN)]2+, ... | Authors: | McQuaid, K.T, Abell, H, Hall, J.P, Cardin, C.J. | Deposit date: | 2016-08-22 | Release date: | 2018-01-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural Studies Reveal Enantiospecific Recognition of a DNA G-Quadruplex by a Ruthenium Polypyridyl Complex. Angew.Chem.Int.Ed.Engl., 58, 2019
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5NBE
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![BU of 5nbe by Molmil](/molmil-images/mine/5nbe) | [Ru(TAP)2(dppz-11-CN)]2+ bound to d(TCGGCGCCGA)2 | Descriptor: | BARIUM ION, DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3'), lambda-[Ru(tap2-dppz-CN)]2+ | Authors: | McQuaid, K.T, Hall, J.P, Cardin, C.J. | Deposit date: | 2017-03-01 | Release date: | 2018-03-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes. Chemistry, 24, 2018
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4JD8
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![BU of 4jd8 by Molmil](/molmil-images/mine/4jd8) | Racemic-[Ru(phen)2(dppz)]2+] bound to synthetic DNA at high resolution | Descriptor: | DNA (5'-D(*AP*TP*GP*CP*AP*T)-3'), Delta-Ru(phen)2(dppz) complex, Lambda-Ru(phen)2(dppz) complex, ... | Authors: | Cook, D.S, Hall, J.P, Cardin, C.J. | Deposit date: | 2013-02-24 | Release date: | 2013-04-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | X-ray Crystal Structure of rac-[Ru(phen)2dppz](2+) with d(ATGCAT)2 Shows Enantiomer Orientations and Water Ordering. J.Am.Chem.Soc., 135, 2013
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7NRP
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![BU of 7nrp by Molmil](/molmil-images/mine/7nrp) | The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG | Descriptor: | CACODYLATE ION, DNA (5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3'), RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-03-04 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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8ASO
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![BU of 8aso by Molmil](/molmil-images/mine/8aso) | Nickel(II) bound to a non-canonical quadruplex | Descriptor: | COBALT HEXAMMINE(III), DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), NICKEL (II) ION | Authors: | Lambert, M.C, Hall, J.P. | Deposit date: | 2022-08-19 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Identifying metal-DNA binding sites, what is the best method to get transition metals into a crystal system? To Be Published
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8ASM
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![BU of 8asm by Molmil](/molmil-images/mine/8asm) | Cobalt(II) bound to a non-canonical quadruplex | Descriptor: | COBALT (II) ION, COBALT HEXAMMINE(III), DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3') | Authors: | Lambert, M.C, Hall, J.P. | Deposit date: | 2022-08-19 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identifying metal-DNA binding sites, what is the best method to get transition metals into a crystal system? To Be Published
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4QIO
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![BU of 4qio by Molmil](/molmil-images/mine/4qio) | Lambda-[Ru(TAP)2(dppz)]2+ bound to d(TCGGCGCCIA) at high resolution | Descriptor: | 5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*IP*A)-3', BARIUM ION, CHLORIDE ION, ... | Authors: | Gurung, S.P, Hall, J.P, Cardin, C.J. | Deposit date: | 2014-06-01 | Release date: | 2015-06-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Inosine Can Increase DNA's Susceptibility to Photo-oxidation by a Ru II Complex due to Structural Change in the Minor Groove. Chemistry, 23, 2017
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7OTB
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![BU of 7otb by Molmil](/molmil-images/mine/7otb) | Ruthenium polypridyl complex bound to a unimolecular chair-form G-quadruplex | Descriptor: | BARIUM ION, DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*TP*GP*GP*G)-3'), POTASSIUM ION, ... | Authors: | McQuaid, K.T, Cardin, C.J, Hall, J.P, Paterson, N.G, Baumgaertner, L. | Deposit date: | 2021-06-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Ruthenium Polypyridyl Complex Bound to a Unimolecular Chair-Form G-Quadruplex. J.Am.Chem.Soc., 144, 2022
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7OOO
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![BU of 7ooo by Molmil](/molmil-images/mine/7ooo) | The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG containing an LNA-Amide-LNA modification | Descriptor: | DNA (5'-D(*CP*TP*(05A)P*TP*CP*TP*TP*TP*G)-3'), MAGNESIUM ION, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-05-28 | Release date: | 2022-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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7OOS
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![BU of 7oos by Molmil](/molmil-images/mine/7oos) | The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG | Descriptor: | DNA (5'-D(*CP*TP*(05K)P*TP*CP*TP*TP*TP*G)-3'), RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3'), STRONTIUM ION | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-05-28 | Release date: | 2022-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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7OZZ
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![BU of 7ozz by Molmil](/molmil-images/mine/7ozz) | The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG with LNA-amide modification | Descriptor: | DNA (5'-D(*CP*TP*(05H)P*TP*CP*TP*TP*TP*G)-3'), POTASSIUM ION, RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3') | Authors: | Thorpe, C, Hardwick, J, McDonough, M.A, Hall, J.P, Baker, Y.R, El-Sagheer, A.H, Brown, T. | Deposit date: | 2021-06-29 | Release date: | 2022-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nat Commun, 13, 2022
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6G8S
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![BU of 6g8s by Molmil](/molmil-images/mine/6g8s) | [Ru(TAP)2(11,12-CN2-dppz)]2+ bound to d(CCGGACCCGG/CCGGGTCCGG)2 | Descriptor: | BARIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*CP*CP*CP*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*GP*TP*CP*CP*GP*G)-3'), ... | Authors: | McQuaid, K.T, Hall, J.P, Cardin, C.J. | Deposit date: | 2018-04-09 | Release date: | 2019-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes. Chemistry, 24, 2018
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3QF8
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![BU of 3qf8 by Molmil](/molmil-images/mine/3qf8) | |
3QRN
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![BU of 3qrn by Molmil](/molmil-images/mine/3qrn) | |