7MBS
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![BU of 7mbs by Molmil](/molmil-images/mine/7mbs) | Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (open state) | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7MBR
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![BU of 7mbr by Molmil](/molmil-images/mine/7mbr) | Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (apo state) | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7MBT
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![BU of 7mbt by Molmil](/molmil-images/mine/7mbt) | Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (low calcium occupancy in the transmembrane domain) | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7MBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mbq by Molmil](/molmil-images/mine/7mbq) | Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7MBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mbu by Molmil](/molmil-images/mine/7mbu) | Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high calcium occupancy in the transmembrane domain) | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7MBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mbv by Molmil](/molmil-images/mine/7mbv) | Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium and 0.5 mM NDNA | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-07-07 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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7MBP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mbp by Molmil](/molmil-images/mine/7mbp) | Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mM EDTA | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | Deposit date: | 2021-04-01 | Release date: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat.Struct.Mol.Biol., 28, 2021
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