8UH1
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1L2A
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![BU of 1l2a by Molmil](/molmil-images/mine/1l2a) | The Crystal Structure and Catalytic Mechanism of Cellobiohydrolase CelS, the Major Enzymatic Component of the Clostridium thermocellum cellulosome | Descriptor: | beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, cellobiohydrolase | Authors: | Guimaraes, B.G, Souchon, H, Lytle, B.L, Wu, J.H.D, Alzari, P.M. | Deposit date: | 2002-02-20 | Release date: | 2002-07-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure and catalytic mechanism of cellobiohydrolase CelS, the major enzymatic component of the Clostridium thermocellum Cellulosome. J.Mol.Biol., 320, 2002
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1L1Y
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![BU of 1l1y by Molmil](/molmil-images/mine/1l1y) | The Crystal Structure and Catalytic Mechanism of Cellobiohydrolase CelS, the Major Enzymatic Component of the Clostridium thermocellum cellulosome | Descriptor: | beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, cellobiohydrolase | Authors: | Guimaraes, B.G, Souchon, H, Lytle, B.L, Wu, J.H.D, Alzari, P.M. | Deposit date: | 2002-02-20 | Release date: | 2002-07-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure and catalytic mechanism of cellobiohydrolase CelS, the major enzymatic component of the Clostridium thermocellum Cellulosome. J.Mol.Biol., 320, 2002
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6OZU
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6MD3
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![BU of 6md3 by Molmil](/molmil-images/mine/6md3) | Structure of T. brucei RRP44 PIN domain | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Rrp44p homologue, ... | Authors: | Guimaraes, B.G, Cesaro, G. | Deposit date: | 2018-09-03 | Release date: | 2019-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Trypanosoma brucei RRP44 is involved in an early stage of large ribosomal subunit RNA maturation. RNA Biol, 16, 2019
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6O7Y
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![BU of 6o7y by Molmil](/molmil-images/mine/6o7y) | Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-4 | Descriptor: | 2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(S)-({(2R,3R,4R,5R)-3-{[(R)-{[(2R,3R,4R,5R)-3-{[(S)-{[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-{[(S)-hydroxy{[(2R,3R,4R,5R)-3-hydroxy-4-methoxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methoxy}phosphoryl]oxy}-4-methoxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-[6-(dimethylamino)-9H-purin-9-yl]-4-methoxytetrahydrofuran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-3H-purin-7-ium, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION | Authors: | Guimaraes, B.G, Reolon, L.W. | Deposit date: | 2019-03-08 | Release date: | 2019-05-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4. Nucleic Acids Res., 47, 2019
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6O80
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6O7Z
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![BU of 6o7z by Molmil](/molmil-images/mine/6o7z) | Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-1 | Descriptor: | 2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(S)-{[(R)-({(2R,3R,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-3-hydroxy-4-methoxytetrahydrofuran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION | Authors: | Guimaraes, B.G, Reolon, L.W. | Deposit date: | 2019-03-08 | Release date: | 2019-05-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4. Nucleic Acids Res., 47, 2019
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2BMX
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![BU of 2bmx by Molmil](/molmil-images/mine/2bmx) | Mycobacterium tuberculosis AhpC | Descriptor: | ALKYL HYDROPEROXIDASE C | Authors: | Guimaraes, B.G, Alzari, P.M. | Deposit date: | 2005-03-16 | Release date: | 2005-05-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and Mechanism of the Alkyl Hydroperoxidase Ahpc, a Key Element of the Mycobacterium Tuberculosis Defense System Against Oxidative Stress. J.Biol.Chem., 280, 2005
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4MPM
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![BU of 4mpm by Molmil](/molmil-images/mine/4mpm) | Wild-type human neuroglobin | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Guimaraes, B.G, Golinelli-Pimpaneau, B. | Deposit date: | 2013-09-13 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The crystal structure of wild-type human brain neuroglobin reveals flexibility of the disulfide bond that regulates oxygen affinity. Acta Crystallogr.,Sect.D, 70, 2014
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3PQJ
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2P38
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4WFS
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![BU of 4wfs by Molmil](/molmil-images/mine/4wfs) | Crystal Structure of tRNA-dihydrouridine(20) synthase catalytic domain | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... | Authors: | Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. | Deposit date: | 2014-09-17 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | An extended dsRBD is required for post-transcriptional modification in human tRNAs. Nucleic Acids Res., 43, 2015
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3D4M
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![BU of 3d4m by Molmil](/molmil-images/mine/3d4m) | Glutaredoxin 2 oxidized structure | Descriptor: | Glutaredoxin-2, mitochondrial | Authors: | Discola, K.F, de Oliveira, M.A, Barcena, J.A, Porras, P, Guimaraes, B.G, Netto, L.E.S. | Deposit date: | 2008-05-14 | Release date: | 2008-10-28 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural aspects of the distinct biochemical properties of glutaredoxin 1 and glutaredoxin 2 from Saccharomyces cerevisiae. J.Mol.Biol., 385, 2009
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2REM
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4P40
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![BU of 4p40 by Molmil](/molmil-images/mine/4p40) | Chlamydia pneumoniae CopN | Descriptor: | CHLORIDE ION, CopN, DIMETHYLAMINE, ... | Authors: | Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B. | Deposit date: | 2014-03-10 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae. J.Biol.Chem., 289, 2014
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4PUF
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![BU of 4puf by Molmil](/molmil-images/mine/4puf) | Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1 | Descriptor: | E3 ubiquitin-protein ligase SlrP, Thioredoxin | Authors: | Zouhir, S, Bernal-Bayard, J, Cordero-Alba, M, Cardenal-Munoz, E, Guimaraes, B, Lazar, N, Ramos-Morales, F, Nessler, S. | Deposit date: | 2014-03-13 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.296 Å) | Cite: | The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family. Biochem.J., 464, 2014
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7TUV
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4G6I
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![BU of 4g6i by Molmil](/molmil-images/mine/4g6i) | Crystallographic structure of trimeric riboflavin synthase from Brucella abortus in complex with roseoflavin | Descriptor: | 1-deoxy-1-[8-(dimethylamino)-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl]-D-ribitol, Riboflavin synthase subunit alpha | Authors: | Serer, M.I, Bonomi, H.R, Guimaraes, B.G, Rossi, R.C, Goldbaum, F.A, Klinke, S. | Deposit date: | 2012-07-19 | Release date: | 2014-03-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility. Acta Crystallogr.,Sect.D, 70, 2014
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4GPK
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![BU of 4gpk by Molmil](/molmil-images/mine/4gpk) | Crystal structure of NprR in complex with its cognate peptide NprX | Descriptor: | NprR, NprX peptide | Authors: | Zouhir, S, Guimaraes, B, Perchat, S, Nicaise, M, Lereclus, D, Nessler, S. | Deposit date: | 2012-08-21 | Release date: | 2013-07-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Peptide-binding dependent conformational changes regulate the transcriptional activity of the quorum-sensor NprR. Nucleic Acids Res., 41, 2013
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3ITJ
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![BU of 3itj by Molmil](/molmil-images/mine/3itj) | Crystal structure of Saccharomyces cerevisiae thioredoxin reductase 1 (Trr1) | Descriptor: | CITRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 1 | Authors: | Oliveira, M.A, Discola, K.F, Alves, S.V, Medrano, F.J, Guimaraes, B.G, Netto, L.E.S. | Deposit date: | 2009-08-28 | Release date: | 2010-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into the specificity of thioredoxin reductase-thioredoxin interactions. A structural and functional investigation of the yeast thioredoxin system. Biochemistry, 49, 2010
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1T13
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![BU of 1t13 by Molmil](/molmil-images/mine/1t13) | Crystal Structure Of Lumazine Synthase From Brucella Abortus Bound To 5-nitro-6-(D-ribitylamino)-2,4(1H,3H) pyrimidinedione | Descriptor: | 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION | Authors: | Klinke, S, Zylberman, V, Vega, D.R, Guimaraes, B.G, Braden, B.C, Goldbaum, F.A. | Deposit date: | 2004-04-15 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystallographic studies on Decameric Brucella spp. Lumazine Synthase: A Novel Quaternary Arrangement Evolved for a New Function? J.Mol.Biol., 353, 2005
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4RQI
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![BU of 4rqi by Molmil](/molmil-images/mine/4rqi) | Structure of TRF2/RAP1 secondary interaction binding site | Descriptor: | GLYCEROL, MAGNESIUM ION, Telomeric repeat-binding factor 2, ... | Authors: | Miron, S, Guimaraes, B, Gaullier, G, Giraud-Panis, M.-J, Gilson, E, Le Du, M.-H. | Deposit date: | 2014-11-03 | Release date: | 2016-02-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4405 Å) | Cite: | A higher-order entity formed by the flexible assembly of RAP1 with TRF2. Nucleic Acids Res., 44, 2016
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7KCJ
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5EPV
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![BU of 5epv by Molmil](/molmil-images/mine/5epv) | Histidine kinase domain from the LOV-HK blue-light receptor from Brucella abortus | Descriptor: | Blue-light-activated histidine kinase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Rinaldi, J, Guimaraes, B.G, Legrand, P, Thompson, A, Paris, G, Goldbaum, F.A, Klinke, S. | Deposit date: | 2015-11-12 | Release date: | 2016-02-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain. J.Mol.Biol., 428, 2016
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