4V9R
| Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | Deposit date: | 2013-12-05 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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4V9S
| Crystal structure of antibiotic GE82832 bound to 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | Deposit date: | 2013-12-05 | Release date: | 2014-07-09 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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5ME1
| Structure of the 30S Pre-Initiation Complex 2 (30S IC-2) Stalled by GE81112 | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | Deposit date: | 2016-11-14 | Release date: | 2017-01-11 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways. Nucleic Acids Res., 45, 2017
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1Z9B
| Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2 | Descriptor: | Translation initiation factor IF-2 | Authors: | Wienk, H, Tomaselli, S, Bernard, C, Spurio, R, Picone, D, Gualerzi, C.O, Boelens, R. | Deposit date: | 2005-04-01 | Release date: | 2005-08-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the C1-subdomain of Bacillus stearothermophilus translation initiation factor IF2 Protein Sci., 14, 2005
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5ME0
| Structure of the 30S Pre-Initiation Complex 1 (30S IC-1) Stalled by GE81112 | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Lopez-Alonso, J.P, Fabbretti, A, Kaminishi, T, Iturrioz, I, Brandi, L, Gil Carton, D, Gualerzi, C, Fucini, P, Connell, S. | Deposit date: | 2016-11-14 | Release date: | 2017-01-11 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways. Nucleic Acids Res., 45, 2017
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3J4J
| Model of full-length T. thermophilus Translation Initiation Factor 2 refined against its cryo-EM density from a 30S Initiation Complex map | Descriptor: | Translation initiation factor IF-2 | Authors: | Simonetti, A, Marzi, S, Billas, I.M.L, Tsai, A, Fabbretti, A, Myasnikov, A, Roblin, P, Vaiana, A.C, Hazemann, I, Eiler, D, Steitz, T.A, Puglisi, J.D, Gualerzi, C.O, Klaholz, B.P. | Deposit date: | 2013-08-26 | Release date: | 2013-09-25 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11.5 Å) | Cite: | Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor. Proc.Natl.Acad.Sci.USA, 110, 2013
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2NBG
| Structure of the Geobacillus stearothermophilus IF2 G3-subdomain | Descriptor: | Translation initiation factor IF-2 | Authors: | Dongre, R, Folkers, G.E, Gualerzi, C.O, Boelens, R, Wienk, H. | Deposit date: | 2016-02-11 | Release date: | 2016-07-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A model for the interaction of the G3-subdomain of Geobacillus stearothermophilus IF2 with the 30S ribosomal subunit. Protein Sci., 25, 2016
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1AH9
| THE STRUCTURE OF THE TRANSLATIONAL INITIATION FACTOR IF1 FROM ESCHERICHIA COLI, NMR, 19 STRUCTURES | Descriptor: | INITIATION FACTOR 1 | Authors: | Sette, M, Van Tilborg, P, Spurio, R, Kaptein, R, Paci, M, Gualerzi, C.O, Boelens, R. | Deposit date: | 1997-04-16 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif. EMBO J., 16, 1997
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2LKC
| Free B.st IF2-G2 | Descriptor: | Translation initiation factor IF-2 | Authors: | Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R. | Deposit date: | 2011-10-10 | Release date: | 2012-02-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Dynamics of Bacterial Translation Initiation Factor IF2. J.Biol.Chem., 287, 2012
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2LKD
| IF2-G2 GDP complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2 | Authors: | Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R. | Deposit date: | 2011-10-10 | Release date: | 2012-02-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Dynamics of Bacterial Translation Initiation Factor IF2. J.Biol.Chem., 287, 2012
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3G8A
| T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoHcy in space group P61 | Descriptor: | Ribosomal RNA small subunit methyltransferase G, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-02-11 | Release date: | 2009-06-30 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG Rna, 15, 2009
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3FUX
| T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with 5'-methylthioadenosine in space group P212121 | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, Dimethyladenosine transferase | Authors: | Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-01-14 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. J.Mol.Biol., 388, 2009
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3FUT
| Apo-form of T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in space group P21212 | Descriptor: | Dimethyladenosine transferase | Authors: | Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-01-14 | Release date: | 2009-03-31 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. J.Mol.Biol., 388, 2009
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3G89
| T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet and AMP in space group P61 | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE | Authors: | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-02-11 | Release date: | 2009-06-30 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG Rna, 15, 2009
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3FUV
| Apo-form of T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in space group P43212 | Descriptor: | Dimethyladenosine transferase | Authors: | Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-01-14 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. J.Mol.Biol., 388, 2009
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3G8B
| T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet in space group I222 | Descriptor: | Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE, SULFATE ION | Authors: | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-02-11 | Release date: | 2009-06-30 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG Rna, 15, 2009
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3G88
| T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet in space group P61 | Descriptor: | DI(HYDROXYETHYL)ETHER, Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE | Authors: | Demirci, H, Belardinelli, R, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-02-11 | Release date: | 2009-06-30 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG Rna, 15, 2009
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3FUU
| T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with Adenosine in space group P212121 | Descriptor: | ADENOSINE, Dimethyladenosine transferase | Authors: | Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-01-14 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. J.Mol.Biol., 388, 2009
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3FUW
| T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in complex with 5'-methylthioadenosine in space group P212121 | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, Dimethyladenosine transferase | Authors: | Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-01-14 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. J.Mol.Biol., 388, 2009
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