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PDB: 36 件

2UXA
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Crystal structure of the GluR2-flip ligand binding domain, r/g unedited.
分子名称: GLUTAMATE RECEPTOR SUBUNIT GLUR2-FLIP, GLUTAMIC ACID, ZINC ION
著者Greger, I.H, Akamine, P, Khatri, L, Ziff, E.B.
登録日2007-03-27
公開日2007-04-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Developmentally Regulated, Combinatorial RNA Processing Modulates Ampa Receptor Biogenesis.
Neuron, 51, 2006
3P3W
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BU of 3p3w by Molmil
Structure of a dimeric GluA3 N-terminal domain (NTD) at 4.2 A resolution
分子名称: Glutamate receptor 3
著者Rossmann, M, Sukumaran, M, Greger, I.H.
登録日2010-10-05
公開日2011-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Dynamics and allosteric potential of the AMPA receptor N-terminal domain
Embo J., 30, 2011
7QHB
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BU of 7qhb by Molmil
Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ...
著者Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H.
登録日2021-12-11
公開日2022-02-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
7QHH
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BU of 7qhh by Molmil
Desensitized state of GluA1/2 AMPA receptor in complex with TARP-gamma 8 (TMD-LBD)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, GLUTAMIC ACID, ...
著者Herguedas, B, Kohegyi, B, Dohrke, J.N, Watson, J.F, Zhang, D, Ho, H, Shaikh, S, Lape, R, Krieger, J.M, Greger, I.H.
登録日2021-12-12
公開日2022-02-23
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor.
Nat Commun, 13, 2022
3HSY
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BU of 3hsy by Molmil
High resolution structure of a dimeric GluR2 N-terminal domain (NTD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, SULFATE ION, ...
著者Rossmann, M, Sukumaran, M, Penn, A.C, Veprintsev, D.B, Greger, I.H.
登録日2009-06-11
公開日2010-06-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers
Embo J., 30, 2011
4GPA
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BU of 4gpa by Molmil
High resolution structure of the GluA4 N-terminal domain (NTD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 4
著者Sukumaran, M, Greger, I.H.
登録日2012-08-20
公開日2012-10-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains.
Structure, 20, 2012
8AYM
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BU of 8aym by Molmil
Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-55511118
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, ...
著者Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H.
登録日2022-09-02
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics.
Nat Commun, 14, 2023
8AYN
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BU of 8ayn by Molmil
Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand LY3130481
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[(1~{S})-1-[1-[5-(2-hydroxyethyloxy)pyridin-2-yl]pyrazol-3-yl]ethyl]-3~{H}-1,3-benzothiazol-2-one, ...
著者Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H.
登録日2022-09-02
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics.
Nat Commun, 14, 2023
8AYO
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BU of 8ayo by Molmil
Open state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and ligand JNJ-61432059
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 5-[2-(4-fluorophenyl)-7-(4-oxidanylpiperidin-1-yl)pyrazolo[1,5-c]pyrimidin-3-yl]-1,3-dihydroindol-2-one, ...
著者Zhang, D, Lape, R, Shaikh, S, Kohegyi, B, Watson, J.F, Cais, O, Nakagawa, T, Greger, I.H.
登録日2022-09-02
公開日2023-04-19
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Modulatory mechanisms of TARP gamma 8-selective AMPA receptor therapeutics.
Nat Commun, 14, 2023
3N6V
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BU of 3n6v by Molmil
Structure of the GluA2 NTD-dimer interface mutant, T78A
分子名称: Glutamate receptor 2
著者Rossmann, M, Sukumaran, M, Greger, I.H.
登録日2010-05-26
公開日2011-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers
Embo J., 30, 2011
3O21
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BU of 3o21 by Molmil
High resolution structure of GluA3 N-terminal domain (NTD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 3, PHOSPHATE ION
著者Rossmann, M, Sukumaran, M, Penn, A.C, Veprintsev, D.B, Babu, M.M, Jensen, M.H, Greger, I.H.
登録日2010-07-22
公開日2011-03-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Dynamics and allosteric potential of the AMPA receptor N-terminal domain
Embo J., 30, 2011
3O2J
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BU of 3o2j by Molmil
Structure of the GluA2 NTD-dimer interface mutant, N54A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Rossmann, M, Sukumaran, M, Penn, A.C, Veprintsev, D.B, Greger, I.H.
登録日2010-07-22
公開日2011-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers
Embo J., 30, 2011
5FWX
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BU of 5fwx by Molmil
Crystal structure of the AMPA receptor GluA2/A4 N-terminal domain heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 4, ...
著者Garcia-Nafria, J, Herguedas, B, Greger, I.H.
登録日2016-02-21
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
5IDE
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BU of 5ide by Molmil
Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model I)
分子名称: Glutamate receptor 2, Glutamate receptor 3
著者Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H.
登録日2016-02-24
公開日2016-03-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.25 Å)
主引用文献Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016
5FWY
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BU of 5fwy by Molmil
Crystal structure of the AMPA receptor GluA2/A3 N-terminal domain heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR 3, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.H.
登録日2016-02-21
公開日2016-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and Organization of Heteromeric Ampa-Type Glutamate Receptors.
Science, 352, 2016
5IDF
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BU of 5idf by Molmil
Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model II)
分子名称: Glutamate receptor 2, Glutamate receptor 3
著者Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H.
登録日2016-02-24
公開日2016-03-16
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (10.31 Å)
主引用文献Structure and organization of heteromeric AMPA-type glutamate receptors.
Science, 352, 2016
9B60
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BU of 9b60 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH8, consensus structure of TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B5Z
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BU of 9b5z by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH8, consensus structure of LBD-TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B64
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BU of 9b64 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH5, class23, structure of LBD-TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B67
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BU of 9b67 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH8, class1, structure of LBD-TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B6A
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BU of 9b6a by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH8, class12, structure of LBD-TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B63
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BU of 9b63 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH5, consensus structure of TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B61
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BU of 9b61 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH5, consensus structure of LBD-TMD-TARPgamma2
分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B69
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BU of 9b69 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH8, class12, structure of NTD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform Flip of Glutamate receptor 2, ...
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024
9B68
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BU of 9b68 by Molmil
GluA2 flip Q in complex with TARPgamma2 at pH8, class1, structure of NTD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform Flip of Glutamate receptor 2, ...
著者Nakagawa, T, Greger, I.H.
登録日2024-03-23
公開日2024-07-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Nat.Struct.Mol.Biol., 31, 2024

 

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