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PDB: 117 件

3B8J
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Q191A mutant of DegS-deltaPDZ
分子名称: Protease degS
著者Grant, R.A, Sohn, J, Sauer, R.T.
登録日2007-11-01
公開日2008-09-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.507 Å)
主引用文献biochemical characterization of DegS-deltaPDZ q191A mutant
To be Published
2V75
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N-terminal domain of Nab2
分子名称: NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN NAB2
著者Grant, R.P, Marshall, N.J, Stewart, M.
登録日2007-07-26
公開日2008-01-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the N-Terminal Mlp1-Binding Domain of the Saccharomyces Cerevisiae Mrna-Binding Protein, Nab2.
J.Mol.Biol., 376, 2008
2BJR
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Crystal structure of the nematode sperm cell motility protein MFP2B
分子名称: MFP2B, SULFATE ION, ZINC ION
著者Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M.
登録日2005-02-07
公開日2005-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility
J.Mol.Biol., 347, 2005
2BJQ
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Crystal structure of the nematode sperm cell motility protein MFP2
分子名称: MFP2A
著者Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M.
登録日2005-02-07
公開日2005-03-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility
J.Mol.Biol., 347, 2005
2JPS
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NAB2 N-terminal domain
分子名称: Nuclear polyadenylated RNA-binding protein NAB2
著者Grant, R, Marshall, N.J, Yang, J, Fasken, M, Kelly, S, Harreman, M.T, Neuhaus, D, Corbett, A.H, Stewart, M.
登録日2007-05-23
公開日2008-03-18
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2
J.Mol.Biol., 376, 2008
1VBB
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POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBC
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POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBD
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POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBE
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POLIOVIRUS (TYPE 3, SABIN STRAIN, MUTANT 242-H2) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBA
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POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1OAI
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Complex between Tap UBA domain and FxFG nucleoporin peptide
分子名称: FXFG NUCLEOPORIN PEPTIDE, NUCLEAR RNA EXPORT FACTOR
著者Grant, R.P, Neuhaus, D, Stewart, M.
登録日2003-01-14
公開日2003-02-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural Basis for the Interaction between the Tap/Nxf1 Uba Domain and Fg Nucleoporins at 1 A Resolution
J.Mol.Biol., 326, 2003
7MX1
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PLK-1 polo-box domain in complex with a high affinity macrocycle synthesized using a novel glutamic acid analog
分子名称: ACE-PRO-LEU-ALA-SER-TPO, N-[(4S)-4,5-diamino-5-oxopentyl]-10-phenyldecanamide, Serine/threonine-protein kinase PLK1
著者Grant, R.A, Hymel, D, Yaffe, M.B, Burke, T.R.
登録日2021-05-17
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles.
Org.Biomol.Chem., 19, 2021
1DPS
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THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA
分子名称: DPS, SODIUM ION
著者Grant, R.A, Filman, D.J, Finkel, S.E, Kolter, R, Hogle, J.M.
登録日1998-02-23
公開日1998-09-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of Dps, a ferritin homolog that binds and protects DNA.
Nat.Struct.Biol., 5, 1998
1TME
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THREE-DIMENSIONAL STRUCTURE OF THEILER VIRUS
分子名称: THEILER'S MURINE ENCEPHALOMYELITIS VIRUS (SUBUNIT VP1), THEILER'S MURINE ENCEPHALOMYELITIS VIRUS (SUBUNIT VP2), THEILER'S MURINE ENCEPHALOMYELITIS VIRUS (SUBUNIT VP3), ...
著者Grant, R.A, Filman, D.J, Hogle, J.M.
登録日1992-01-30
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Three-dimensional structure of Theiler virus.
Proc.Natl.Acad.Sci.USA, 89, 1992
1DU0
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ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX
分子名称: DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3'), ENGRAILED HOMEODOMAIN
著者Grant, R.A, Rould, M.A, Klemm, J.D, Pabo, C.O.
登録日2000-01-13
公開日2000-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
Biochemistry, 39, 2000
2PIE
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Crystal structure of the FHA domain of RNF8 in complex with its optimal phosphopeptide
分子名称: E3 ubiquitin-protein ligase RNF8, phosphopeptide
著者Grant, R.A, Yaffe, M.B.
登録日2007-04-13
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly.
Cell(Cambridge,Mass.), 131, 2007
4X9V
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PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3C
分子名称: Phosphopeptide macrocycle 3C, Serine/threonine-protein kinase PLK1
著者Grant, R.A, Qian, W.-J, Yaffe, M.B, Burke, T.R.
登録日2014-12-11
公開日2015-07-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.429 Å)
主引用文献Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.
Biopolymers, 104, 2015
4X9W
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PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 4C
分子名称: Macrocyclic phosphopeptide 4C, Serine/threonine-protein kinase PLK1
著者Grant, R.A, Qian, W.-J, Yaffe, M.B, Burke, T.R.
登録日2014-12-11
公開日2015-07-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.
Biopolymers, 104, 2015
4X9R
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PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3B
分子名称: Phosphopeptide macrocycle 3B, Serine/threonine-protein kinase PLK1
著者Grant, R.A, Qian, W.-J, Yaffe, M.B, Burke, T.R.
登録日2014-12-11
公開日2015-07-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.398 Å)
主引用文献Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.
Biopolymers, 104, 2015
1GO5
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Structure of the C-terminal FG-binding domain of human Tap
分子名称: TIP ASSOCIATING PROTEIN
著者Grant, R.P, Hurt, E, Neuhaus, D, Stewart, M.
登録日2001-10-18
公開日2002-02-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the C-Terminal Fg-Nucleoporin Binding Domain of Tap/Nxf1
Nat.Struct.Biol., 9, 2002
6AX4
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Plk-1 polo-box domain in complex with histidine N(tau)-cyclized Macrocycle 5b.
分子名称: AMYLAMINE, Serine/threonine-protein kinase PLK1, histidine N(tau)-cyclized Macrocycle 5b
著者Grant, R.A, Hymel, D, Yaffe, M.B, Burke, T.R.
登録日2017-09-06
公開日2018-09-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Histidine N( tau )-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors.
Bioorg. Med. Chem. Lett., 28, 2018
6OTT
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Structure of PurF in complex with ppApp
分子名称: Amidophosphoribosyltransferase, PurF, MAGNESIUM ION, ...
著者Grant, R.A, Wang, B, Laub, M.T.
登録日2019-05-03
公開日2019-11-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp.
Nature, 575, 2019
5JI3
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HslUV complex
分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV
著者Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
登録日2016-04-21
公開日2016-12-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
5JI2
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HslU L199Q in HslUV complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ...
著者Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V.
登録日2016-04-21
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
5TXV
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HslU P21 cell with 4 hexamers
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU
著者Grant, R.A, Chen, J, Glynn, S.E, Sauer, R.T.
登録日2016-11-17
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (7.086 Å)
主引用文献Covalently linked HslU hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding and translocation.
J. Biol. Chem., 292, 2017

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件を2024-09-04に公開中

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