1EYV
 
 | | THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG, PHOSPHATE ION | | Authors: | Gopal, B, Haire, L.F, Cox, R.A, Colston, M.J, Major, S, Brannigan, J.A, Smerdon, S.J, Dodson, G.G, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2000-05-09 | | Release date: | 2000-05-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The crystal structure of NusB from Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
|
|
1K0R
 | | Crystal Structure of Mycobacterium tuberculosis NusA | | Descriptor: | NusA, SULFATE ION | | Authors: | Gopal, B, Haire, L.F, Gamblin, S.J, Dodson, E.J, Lane, A.N, Papavinasasundaram, K.G, Colston, M.J, Dodson, G, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2001-09-20 | | Release date: | 2001-12-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.
J.Mol.Biol., 314, 2001
|
|
4XXE
 | | Structure of AgrA LytTR domain in complex with promoters | | Descriptor: | Accessory gene regulator A, DNA (5'-D(*AP*TP*TP*GP*CP*CP*TP*AP*AP*CP*TP*GP*TP*AP*G)-3'), DNA (5'-D(P*TP*AP*CP*AP*GP*TP*TP*AP*GP*GP*CP*AP*A)-3'), ... | | Authors: | Gopal, B, Rajasree, K. | | Deposit date: | 2015-01-30 | | Release date: | 2016-04-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
|
|
1Y3T
 | | Crystal structure of YxaG, a dioxygenase from Bacillus subtilis | | Descriptor: | FE (III) ION, Hypothetical protein yxaG | | Authors: | Gopal, B, Madan, L.L, Betz, S.F, Kossiakoff, A.A. | | Deposit date: | 2004-11-26 | | Release date: | 2005-01-18 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)
Biochemistry, 44, 2005
|
|
4XQQ
 | | Crystal structure of AgrA LytTR domain in complex with promoters | | Descriptor: | Accessory gene regulator A, DNA (5'-D(*AP*TP*TP*TP*CP*TP*TP*AP*AP*CP*TP*AP*GP*TP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*AP*CP*TP*AP*GP*TP*TP*AP*AP*GP*AP*AP*A)-3') | | Authors: | Gopal, B, Rajasree, K. | | Deposit date: | 2015-01-19 | | Release date: | 2016-04-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
|
|
4XQN
 | | Crystal structure of AgrA LytTR domain in complex with promoters | | Descriptor: | 1,2-ETHANEDIOL, Accessory gene regulator A, DNA (5'-D(*AP*CP*AP*GP*TP*TP*AP*AP*GP*AP*AP*T)-3'), ... | | Authors: | Gopal, B, Rajasree, K. | | Deposit date: | 2015-01-19 | | Release date: | 2016-04-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
|
|
4XYO
 | | Structure of AgrA LytTR domain | | Descriptor: | 1,2-ETHANEDIOL, Accessory gene regulator A | | Authors: | Gopal, B, Rajasree, K. | | Deposit date: | 2015-02-02 | | Release date: | 2016-04-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
|
|
4XQJ
 | | Crystal structure of AgrA LytTR domain in complex with promoters | | Descriptor: | 1,2-ETHANEDIOL, Accessory gene regulator A, CALCIUM ION, ... | | Authors: | Gopal, B, Rajasree, K. | | Deposit date: | 2015-01-19 | | Release date: | 2016-04-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
|
|
4XYQ
 | | Structure of AgrA LytTR domain in complex with promoters | | Descriptor: | 1,2-ETHANEDIOL, Accessory gene regulator A, DNA (5'-D(*AP*AP*TP*AP*CP*TP*TP*AP*AP*CP*TP*GP*TP*TP*AP*A)-3'), ... | | Authors: | Gopal, B, Rajasree, K. | | Deposit date: | 2015-02-03 | | Release date: | 2016-04-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression.
Biochem Biophys Rep, 6, 2016
|
|
3KX0
 | | Crystal Structure of the PAS domain of Rv1364c | | Descriptor: | ISOPROPYL ALCOHOL, Uncharacterized protein Rv1364c/MT1410 | | Authors: | Jaiswal, R.K, Gopal, B. | | Deposit date: | 2009-12-02 | | Release date: | 2010-06-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Role of a PAS sensor domain in the Mycobacterium tuberculosis transcription regulator Rv1364c
Biochem.Biophys.Res.Commun., 398, 2010
|
|
5J5D
 | |
5ITW
 | | Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase | | Descriptor: | Dihydroanticapsin 7-dehydrogenase, SULFATE ION | | Authors: | Perinbam, K, Balaram, H, Row, T.N.G, Gopal, B. | | Deposit date: | 2016-03-17 | | Release date: | 2017-02-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC.
Protein Eng. Des. Sel., 30, 2017
|
|
5ITV
 | | Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase in complex with NADH | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Dihydroanticapsin 7-dehydrogenase | | Authors: | Perinbam, K, Balaram, H, Row, T.N.G, Gopal, B. | | Deposit date: | 2016-03-17 | | Release date: | 2017-02-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Probing the influence of non-covalent contact networks identified by charge density analysis on the oxidoreductase BacC.
Protein Eng. Des. Sel., 30, 2017
|
|
4EWT
 | | The crystal structure of a putative aminohydrolase from methicillin resistant Staphylococcus aureus | | Descriptor: | 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | | Authors: | Girish, T.S, Vivek, B, Colaco, M, Misquith, S, Gopal, B. | | Deposit date: | 2012-04-27 | | Release date: | 2013-02-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of an amidohydrolase, SACOL0085, from methicillin-resistant Staphylococcus aureus COL
Acta Crystallogr.,Sect.F, 69, 2013
|
|
4BXI
 | | Crystal structure of ATP binding domain of AgrC from Staphylococcus aureus | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACCESSORY GENE REGULATOR PROTEIN C, ACETATE ION, ... | | Authors: | Srivastava, S.K, Rajasree, K, Gopal, B. | | Deposit date: | 2013-07-12 | | Release date: | 2014-06-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Influence of the Agrc-Agra Complex in the Response Time of Staphylococcus Aureus Quorum Sensing
J.Bacteriol., 196, 2014
|
|
5XE7
 | |
7F5Y
 | | Crystal structure of the single-stranded dna-binding protein from Mycobacterium tuberculosis- Form III | | Descriptor: | FORMIC ACID, Single-stranded DNA-binding protein | | Authors: | Srikalaivani, R, Paul, A, Sriram, R, Narayanan, S, Gopal, B, Vijayan, M. | | Deposit date: | 2021-06-23 | | Release date: | 2022-05-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural variability of Mycobacterium tuberculosis SSB and susceptibility to inhibition.
Curr.Sci., 122, 2022
|
|
7F5Z
 | | Crystal structure of the single-stranded dna-binding protein from Mycobacterium tuberculosis- Form III | | Descriptor: | Single-stranded DNA-binding protein | | Authors: | Srikalaivani, R, Paul, A, Sriram, R, Narayanan, S, Gopal, B, Vijayan, M. | | Deposit date: | 2021-06-23 | | Release date: | 2022-05-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural variability of Mycobacterium tuberculosis SSB and susceptibility to inhibition.
Curr.Sci., 122, 2022
|
|
7ESS
 | | Structure-guided studies of the Holliday junction resolvase RuvX provide novel insights into ATP-stimulated cleavage of branched DNA and RNA substrates | | Descriptor: | Putative pre-16S rRNA nuclease | | Authors: | Thakur, M, Mohan, D, Singh, A.K, Agarwal, A, Gopal, B, Muniyappa, K. | | Deposit date: | 2021-05-11 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Novel insights into ATP-Stimulated Cleavage of branched DNA and RNA Substrates through Structure-Guided Studies of the Holliday Junction Resolvase RuvX.
J.Mol.Biol., 433, 2021
|
|
8I61
 | | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid and Citric acid, Form I | | Descriptor: | 1,2-ETHANEDIOL, BARBITURIC ACID, CITRIC ACID, ... | | Authors: | Raj, P, Paul, A, Gopal, B. | | Deposit date: | 2023-01-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.
Eur.J.Med.Chem., 258, 2023
|
|
8I67
 | | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 2,4-Thiazolidinedione, Form I | | Descriptor: | 1,2-ETHANEDIOL, 1,3-thiazolidine-2,4-dione, Uracil-DNA glycosylase | | Authors: | Raj, P, Paul, A, Gopal, B. | | Deposit date: | 2023-01-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.
Eur.J.Med.Chem., 258, 2023
|
|
8I69
 | | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Fluoroorotic acid and Citric acid, Form I | | Descriptor: | 1,2-ETHANEDIOL, 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CITRIC ACID, ... | | Authors: | Raj, P, Paul, A, Gopal, B. | | Deposit date: | 2023-01-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.
Eur.J.Med.Chem., 258, 2023
|
|
8I6B
 | | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Hydroxy-2,4(1H,3H)-pyrimidinedione, Form I | | Descriptor: | 1,2-ETHANEDIOL, 5-oxidanyl-1~{H}-pyrimidine-2,4-dione, CHLORIDE ION, ... | | Authors: | Raj, P, Paul, A, Gopal, B. | | Deposit date: | 2023-01-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.
Eur.J.Med.Chem., 258, 2023
|
|
8I63
 | | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form III | | Descriptor: | 1,2-ETHANEDIOL, BARBITURIC ACID, Uracil-DNA glycosylase | | Authors: | Raj, P, Paul, A, Gopal, B. | | Deposit date: | 2023-01-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.
Eur.J.Med.Chem., 258, 2023
|
|
8I66
 | | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid) and citric acid, Form I | | Descriptor: | 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, CITRIC ACID, Uracil-DNA glycosylase | | Authors: | Raj, P, Paul, A, Gopal, B. | | Deposit date: | 2023-01-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment.
Eur.J.Med.Chem., 258, 2023
|
|
