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PDB: 5 results

1QMN
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BU of 1qmn by Molmil
Alpha1-antichymotrypsin serpin in the delta conformation (partial loop insertion)
Descriptor: ALPHA-1-ANTICHYMOTRYPSIN
Authors:Gooptu, B, Hazes, B, Lomas, D.A.
Deposit date:1999-10-04
Release date:2000-01-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two-Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease
Proc.Natl.Acad.Sci.USA, 97, 2000
3DRM
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BU of 3drm by Molmil
2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin
Descriptor: Alpha-1-antitrypsin
Authors:Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
Deposit date:2008-07-11
Release date:2009-03-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DRU
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Crystal Structure of Gly117Phe Alpha1-Antitrypsin
Descriptor: Alpha-1-antitrypsin
Authors:Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
Deposit date:2008-07-11
Release date:2009-03-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3NE4
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1.8 Angstrom structure of intact native wild-type alpha-1-antitrypsin
Descriptor: Alpha-1-antitrypsin
Authors:Patschull, A.O.M, Gooptu, B, Segu, L.
Deposit date:2010-06-08
Release date:2011-12-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Therapeutic target-site variability in [alpha]1-antitrypsin characterized at high resolution
Acta Crystallogr.,Sect.F, 67, 2011
4PYW
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BU of 4pyw by Molmil
1.92 angstrom crystal structure of A1AT:TTAI ternary complex
Descriptor: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL
Authors:Nyon, M.P, Day, J, Gooptu, B.
Deposit date:2014-03-28
Release date:2015-06-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015

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