1RWL
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![BU of 1rwl by Molmil](/molmil-images/mine/1rwl) | Extracellular domain of Mycobacterium tuberculosis PknD | 分子名称: | CADMIUM ION, Serine/threonine-protein kinase pknD | 著者 | Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-12-16 | 公開日 | 2004-04-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller. J.Mol.Biol., 339, 2004
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1RWI
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![BU of 1rwi by Molmil](/molmil-images/mine/1rwi) | Extracellular domain of Mycobacterium tuberculosis PknD | 分子名称: | CADMIUM ION, Serine/threonine-protein kinase pknD | 著者 | Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-12-16 | 公開日 | 2004-04-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller. J.Mol.Biol., 339, 2004
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3ORP
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![BU of 3orp by Molmil](/molmil-images/mine/3orp) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 5) | 分子名称: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | 著者 | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-09-07 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3ORO
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![BU of 3oro by Molmil](/molmil-images/mine/3oro) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 4) | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | 著者 | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-09-07 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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3ORT
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![BU of 3ort by Molmil](/molmil-images/mine/3ort) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 6) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | 著者 | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-09-07 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3FZE
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![BU of 3fze by Molmil](/molmil-images/mine/3fze) | Structure of the 'minimal scaffold' (ms) domain of Ste5 that cocatalyzes Fus3 phosphorylation by Ste7 | 分子名称: | Protein STE5 | 著者 | Good, M.C, Tang, G, Singleton, J, Remenyi, A, Lim, W.A. | 登録日 | 2009-01-25 | 公開日 | 2009-03-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation. Cell(Cambridge,Mass.), 136, 2009
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1TXO
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![BU of 1txo by Molmil](/molmil-images/mine/1txo) | Crystal structure of the Mycobacterium tuberculosis serine/threonine phosphatase PstP/Ppp at 1.95 A. | 分子名称: | MANGANESE (II) ION, Putative Bacterial Enzyme | 著者 | Pullen, K.E, Ng, H.L, Sung, P.Y, Good, M.C, Smith, S.M, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-07-05 | 公開日 | 2004-11-23 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | An Alternate Conformation and a Third Metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr Protein Phosphatase. Structure, 12, 2004
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2B9H
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![BU of 2b9h by Molmil](/molmil-images/mine/2b9h) | Crystal structure of Fus3 with a docking motif from Ste7 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3, ... | 著者 | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | 登録日 | 2005-10-11 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2B9F
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![BU of 2b9f by Molmil](/molmil-images/mine/2b9f) | Crystal structure of non-phosphorylated Fus3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3 | 著者 | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | 登録日 | 2005-10-11 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2B9I
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![BU of 2b9i by Molmil](/molmil-images/mine/2b9i) | Crystal structure of Fus3 with a docking motif from Msg5 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3, ... | 著者 | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | 登録日 | 2005-10-11 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2B9J
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![BU of 2b9j by Molmil](/molmil-images/mine/2b9j) | Crystal structure of Fus3 with a docking motif from Far1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cyclin-dependent kinase inhibitor FAR1, MAGNESIUM ION, ... | 著者 | Remenyi, A, Good, M.C, Bhattacharyya, R.P, Lim, W.A. | 登録日 | 2005-10-11 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network. Mol.Cell, 20, 2005
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2F9G
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![BU of 2f9g by Molmil](/molmil-images/mine/2f9g) | Crystal structure of Fus3 phosphorylated on Tyr182 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitogen-activated protein kinase FUS3 | 著者 | Bhattacharyya, R.P, Remenyi, A, Good, M.C, Bashor, C.J, Falick, A.M, Lim, W.A. | 登録日 | 2005-12-05 | 公開日 | 2006-11-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Science, 311, 2006
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2FA2
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![BU of 2fa2 by Molmil](/molmil-images/mine/2fa2) | Crystal structure of Fus3 without a peptide from Ste5 | 分子名称: | Mitogen-activated protein kinase FUS3, THIOCYANATE ION | 著者 | Bhattacharyya, R.P, Remenyi, A, Good, M.C, Bashor, C.J, Falick, A.M, Lim, W.A. | 登録日 | 2005-12-06 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway Science, 311, 2006
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3ORI
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![BU of 3ori by Molmil](/molmil-images/mine/3ori) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 1) | 分子名称: | MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | 著者 | Lombana, T.N, Echols, N, Good, M.C, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-09-07 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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5W58
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![BU of 5w58 by Molmil](/molmil-images/mine/5w58) | Crystal Complex of Cyclooxygenase-2: (S)-ARN-2508 (a dual COX and FAAH inhibitor) | 分子名称: | (2S)-2-{2-fluoro-3'-[(hexylcarbamoyl)oxy][1,1'-biphenyl]-4-yl}propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Xu, S, Goodman, M.C, Banerjee, S, Piomelli, D, Marnett, L.J. | 登録日 | 2017-06-14 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.267 Å) | 主引用文献 | Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site. J. Biol. Chem., 293, 2018
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8ET0
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![BU of 8et0 by Molmil](/molmil-images/mine/8et0) | Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IBUPROFEN, ... | 著者 | Xu, S, Banerjee, S, Uddin, M.J, Goodman, M.C, Marnett, L.J. | 登録日 | 2022-10-15 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal complex of murine cycloxygenase-2 with alpaca nanobody F9 To Be Published
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4NAZ
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![BU of 4naz by Molmil](/molmil-images/mine/4naz) | Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom Resolution | 分子名称: | GLYCEROL, Metallothiol transferase FosB, SULFATE ION, ... | 著者 | Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N. | 登録日 | 2013-10-22 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
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4NB1
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![BU of 4nb1 by Molmil](/molmil-images/mine/4nb1) | Crystal Structure of FosB from Staphylococcus aureus at 1.80 Angstrom Resolution with L-Cysteine-Cys9 Disulfide | 分子名称: | CYSTEINE, Metallothiol transferase FosB, SULFATE ION | 著者 | Cook, P.D, Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Armstrong, R.N. | 登録日 | 2013-10-22 | 公開日 | 2014-02-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
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4NAY
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![BU of 4nay by Molmil](/molmil-images/mine/4nay) | Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.42 Angstrom Resolution - SAD Phasing | 分子名称: | Metallothiol transferase FosB, SULFATE ION, ZINC ION | 著者 | Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N. | 登録日 | 2013-10-22 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
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4NB2
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![BU of 4nb2 by Molmil](/molmil-images/mine/4nb2) | Crystal Structure of FosB from Staphylococcus aureus at 1.89 Angstrom Resolution - Apo structure | 分子名称: | Metallothiol transferase FosB, SULFATE ION | 著者 | Cook, P.D, Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Armstrong, R.N. | 登録日 | 2013-10-22 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
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4NB0
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![BU of 4nb0 by Molmil](/molmil-images/mine/4nb0) | Crystal Structure of FosB from Staphylococcus aureus with BS-Cys9 disulfide at 1.62 Angstrom Resolution | 分子名称: | CYSTEINE, GLYCEROL, Metallothiol transferase FosB, ... | 著者 | Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N. | 登録日 | 2013-10-22 | 公開日 | 2014-02-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
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