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PDB: 12 件
7RAH
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BU of 7rah by Molmil
Adenylate cyclase toxin RTX domain fragment bound to M1H5 Fab and M2B10 Fab
分子名称: Bifunctional adenylate cyclase toxin/hemolysin CyaA,Bifunctional adenylate cyclase toxin/hemolysin CyaA, CALCIUM ION, M1H5 Fab Heavy Chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2021-07-01
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes.
Plos Pathog., 17, 2021
7USM
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BU of 7usm by Molmil
Integrin alphaM/beta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7USL
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BU of 7usl by Molmil
Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
8TCO
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BU of 8tco by Molmil
HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CS2it1p2_F7K Fab heavy chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2023-07-02
公開日2023-08-09
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
8TEA
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BU of 8tea by Molmil
HCMV Pentamer in complex with CS2pt1p2_A10L Fab and CS3pt1p4_C1L Fab
分子名称: CS2pt1p2_A10L Fab heavy chain, CS2pt1p2_A10L Fab light chain, CS3pt1p4_C1L Fab heavy chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2023-07-05
公開日2023-08-09
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
8DCN
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BU of 8dcn by Molmil
Crystal structure of Clostridioides difficile binary toxin CDTb D4 fragment in complex with BINTOXB/9 Fab
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/9 Fab heavy chain, BINTOXB/9 Fab light chain
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-06-16
公開日2023-04-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
7S3N
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BU of 7s3n by Molmil
SARS-CoV-2 S stem helix peptide bound to Fab22
分子名称: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
著者Goldsmith, J.A, McLellan, J.S.
登録日2021-09-07
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
7S3M
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BU of 7s3m by Molmil
MERS-CoV S stem helix peptide bound to Fab22
分子名称: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
著者Goldsmith, J.A, McLellan, J.S.
登録日2021-09-07
公開日2021-10-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
7L3N
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BU of 7l3n by Molmil
SARS-CoV 2 Spike Protein bound to LY-CoV555
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2020-12-18
公開日2021-02-03
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection.
Biorxiv, 2020
6XKL
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BU of 6xkl by Molmil
SARS-CoV-2 HexaPro S One RBD up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wrapp, D, Hsieh, C.-L, Goldsmith, J.A, McLellan, J.S.
登録日2020-06-26
公開日2020-07-15
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Science, 369, 2020
6VSB
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BU of 6vsb by Molmil
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wrapp, D, Wang, N, Corbett, K.S, Goldsmith, J.A, Hsieh, C, Abiona, O, Graham, B.S, McLellan, J.S.
登録日2020-02-10
公開日2020-02-26
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020

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件を2024-10-30に公開中

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