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PDB: 8 件

1QQS
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NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN HOMODIMER
分子名称: DECANOIC ACID, NEUTROPHIL GELATINASE, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Goetz, D.H, Willie, S.T, Armen, R, Bratt, T, Borregaard, N, Strong, R.K.
登録日1999-06-07
公開日2000-04-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin
Biochemistry, 39, 2000
1L6M
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Neutrophil Gelatinase-associated Lipocalin is a Novel Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition
分子名称: 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, FE (III) ION, ...
著者Goetz, D.H, Borregaard, N, Bluhm, M.E, Raymond, K.N, Strong, R.K.
登録日2002-03-11
公開日2003-03-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Neutrophil Lipocalin NGAL is a Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition
Mol.Cell, 10, 2002
1DFV
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CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN MONOMER
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN NEUTROPHIL GELATINASE, ...
著者Goetz, D.H, Willie, S.T, Armen, R.S, Bratt, T, Borregaard, N, Strong, R.K.
登録日1999-11-22
公開日2000-03-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin
Biochemistry, 39, 2000
2OP9
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Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus
分子名称: NALPHA-[(BENZYLOXY)CARBONYL]-N-[(1R)-4-HYDROXY-1-METHYL-2-OXOBUTYL]-L-PHENYLALANINAMIDE, Replicase polyprotein 1ab (pp1ab, ORF1AB) 3C-like proteinase (3CL-PRO, ...
著者Craik, C.S, Goetz, D.H.
登録日2007-01-27
公開日2007-07-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus.
Biochemistry, 46, 2007
2PBK
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Crystal structure of KSHV protease in complex with hexapeptide phosphonate inhibitor
分子名称: ACETATE ION, KSHV protease, hexapeptide phosphonate inhibitor
著者Lazic, A, Goetz, D.H.
登録日2007-03-28
公開日2007-12-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Substrate modulation of enzyme activity in the herpesvirus protease family.
J.Mol.Biol., 373, 2007
1ORF
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The Oligomeric Structure of Human Granzyme A Reveals the Molecular Determinants of Substrate Specificity
分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Granzyme A, SULFATE ION
著者Bell, J.K, Goetz, D.H, Mahrus, S, Harris, J.L, Fletterick, R.J, Craik, C.S.
登録日2003-03-12
公開日2003-07-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.
Nat.Struct.Biol., 10, 2003
3SO3
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Structures of Fab-Protease Complexes Reveal a Highly Specific Non-Canonical Mechanism of Inhibition.
分子名称: A11 FAB heavy chain, A11 FAB light chain, GLYCEROL, ...
著者Schneider, E.L, Farady, C.J, Egea, P.F, Goetz, D.H, Baharuddin, A, Craik, C.S.
登録日2011-06-29
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A reverse binding motif that contributes to specific protease inhibition by antibodies.
J.Mol.Biol., 415, 2012
3BN9
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Crystal Structure of MT-SP1 in complex with Fab Inhibitor E2
分子名称: 1,2-ETHANEDIOL, E2 Fab Heavy Chain, E2 Fab Light Chain, ...
著者Farady, C.J, Schneider, E.L, Egea, P.F, Goetz, D.H, Craik, C.S.
登録日2007-12-13
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.173 Å)
主引用文献Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition
J.Mol.Biol., 380, 2008

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件を2024-08-07に公開中

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