8OST
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![BU of 8ost by Molmil](/molmil-images/mine/8ost) | Structure of human terminal uridylyltransferase 4 (TUT4, ZCCHC11) in complex with pre-let7g miRNA and Lin28A | Descriptor: | Protein lin-28 homolog A, Terminal uridylyltransferase 4, ZINC ION, ... | Authors: | Gilbert, R.J, Yi, G, Ye, M. | Deposit date: | 2023-04-20 | Release date: | 2024-07-17 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs. Nat.Struct.Mol.Biol., 2024
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8OEF
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4UD4
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![BU of 4ud4 by Molmil](/molmil-images/mine/4ud4) | Structural Plasticity of Cid1 Provides a Basis for its RNA Terminal Uridylyl Transferase Activity | Descriptor: | GLYCEROL, POLY(A) RNA POLYMERASE PROTEIN CID1 | Authors: | Yates, L.A, Durrant, B.P, Fleurdepine, S, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2014-12-07 | Release date: | 2015-03-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural plasticity of Cid1 provides a basis for its distributive RNA terminal uridylyl transferase activity. Nucleic Acids Res., 43, 2015
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6SB1
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![BU of 6sb1 by Molmil](/molmil-images/mine/6sb1) | Crystal structure of murine perforin-2 P2 domain crystal form 1 | Descriptor: | CHLORIDE ION, GLYCEROL, Macrophage-expressed gene 1 protein | Authors: | Ni, T, Ginger, L, Gilbert, R.J.C. | Deposit date: | 2019-07-18 | Release date: | 2020-02-05 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. Sci Adv, 6, 2020
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6SB3
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6SB4
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![BU of 6sb4 by Molmil](/molmil-images/mine/6sb4) | Crystal structure of murine perforin-2 P2 domain crystal form 2 | Descriptor: | Macrophage-expressed gene 1 protein | Authors: | Ni, T, Yu, X, Ginger, L, Gilbert, R.J.C. | Deposit date: | 2019-07-18 | Release date: | 2020-02-05 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. Sci Adv, 6, 2020
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6SB5
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4JGZ
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![BU of 4jgz by Molmil](/molmil-images/mine/4jgz) | Crystal structure of human coxsackievirus A16 uncoating intermediate (space group I222) | Descriptor: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | Authors: | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, McAuley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | Deposit date: | 2013-03-04 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Picornavirus uncoating intermediate captured in atomic detail. Nat Commun, 4, 2013
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4JGY
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![BU of 4jgy by Molmil](/molmil-images/mine/4jgy) | Crystal structure of human coxsackievirus A16 uncoating intermediate (space group P4232) | Descriptor: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | Authors: | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, Mcauley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | Deposit date: | 2013-03-04 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Picornavirus uncoating intermediate captured in atomic detail. Nat Commun, 4, 2013
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5J67
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![BU of 5j67 by Molmil](/molmil-images/mine/5j67) | Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | Authors: | Ni, T, Harlos, K, Gilbert, R.J.C. | Deposit date: | 2016-04-04 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biology, 6, 2016
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5J69
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5J68
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![BU of 5j68 by Molmil](/molmil-images/mine/5j68) | Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | Authors: | Ni, T, Harlos, K, Gilbert, R.J.C. | Deposit date: | 2016-04-04 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (5.221 Å) | Cite: | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biology, 6, 2016
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4UD5
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![BU of 4ud5 by Molmil](/molmil-images/mine/4ud5) | Structural Plasticity of Cid1 Provides a Basis for its RNA Terminal Uridylyl Transferase Activity | Descriptor: | POLY(A) RNA POLYMERASE PROTEIN CID1 | Authors: | Yates, L.A, Durrant, B.P, Fleurdepine, S, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2014-12-07 | Release date: | 2015-03-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural Plasticity of Cid1 Provides a Basis for its Distributive RNA Terminal Uridylyl Transferase Activity. Nucleic Acids Res., 43, 2015
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5L5N
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![BU of 5l5n by Molmil](/molmil-images/mine/5l5n) | Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8.5 angstrom, spacegroup P4(3)22 | Descriptor: | Plexin-A4 | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (8.502 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L5G
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![BU of 5l5g by Molmil](/molmil-images/mine/5l5g) | Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom | Descriptor: | Plexin-A2 | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (10 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L5M
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![BU of 5l5m by Molmil](/molmil-images/mine/5l5m) | Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8 angstrom, spacegroup P4(3)2(1)2 | Descriptor: | Plexin-A4 | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (8 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L74
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![BU of 5l74 by Molmil](/molmil-images/mine/5l74) | Plexin A2 extracellular segment domains 4-5 (PSI2-IPT2), resolution 1.36 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Plexin-A2, ... | Authors: | Kong, Y, Janssen, B.J.C, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-06-01 | Release date: | 2017-03-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L7N
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![BU of 5l7n by Molmil](/molmil-images/mine/5l7n) | Plexin A1 extracellular fragment, domains 7-10 (IPT3-IPT6) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kong, Y, Janssen, B.J.C, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-06-03 | Release date: | 2017-03-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L59
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![BU of 5l59 by Molmil](/molmil-images/mine/5l59) | Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P2(1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L5K
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![BU of 5l5k by Molmil](/molmil-images/mine/5l5k) | Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1) | Descriptor: | Plexin-A4 | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (7.501 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L5L
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![BU of 5l5l by Molmil](/molmil-images/mine/5l5l) | Plexin A4 full extracellular region, domains 1 to 8 modeled, data to 8 angstrom, spacegroup P2(1) | Descriptor: | Plexin-A4 | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (8.001 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L5C
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![BU of 5l5c by Molmil](/molmil-images/mine/5l5c) | Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P4(3)2(1)2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, ... | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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5L56
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![BU of 5l56 by Molmil](/molmil-images/mine/5l56) | Plexin A1 full extracellular region, domains 1 to 10, to 4 angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2016-05-28 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
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4BBK
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![BU of 4bbk by Molmil](/molmil-images/mine/4bbk) | Structural and functional characterisation of the kindlin-1 pleckstrin homology domain | Descriptor: | FERMITIN FAMILY HOMOLOG 1, GLYCEROL | Authors: | Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C. | Deposit date: | 2012-09-25 | Release date: | 2012-11-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain J.Biol.Chem., 287, 2012
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8X7T
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![BU of 8x7t by Molmil](/molmil-images/mine/8x7t) | MCM in the Apo state. | Descriptor: | mini-chromosome maintenance complex 3 | Authors: | Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Gilbert, R.J.C, Zhang, P. | Deposit date: | 2023-11-25 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | MCM in the Apo state To Be Published
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