8G1P
 
 | | Co-crystal structure of Compound 11 in complex with the bromodomain of human SMARCA2 and pVHL:ElonginC:ElonginB | | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | 著者 | Ghimire Rijal, S, Wurz, R.P, Vaish, A. | | 登録日 | 2023-02-02 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation.
Nat Commun, 14, 2023
|
|
8G1Q
 | | Co-crystal structure of Compound 1 in complex with the bromodomain of human SMARCA4 and pVHL:ElonginC:ElonginB | | 分子名称: | DI(HYDROXYETHYL)ETHER, Elongin-B, Elongin-C, ... | | 著者 | Ghimire Rijal, S, Wurz, R.P, Vaish, A. | | 登録日 | 2023-02-02 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.73 Å) | | 主引用文献 | Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation.
Nat Commun, 14, 2023
|
|
5HM4
 | | Crystal structure of oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1226) from THERMOTOGA MARITIMA at 2.0 A resolution | | 分子名称: | CALCIUM ION, Mannoside ABC transport system, sugar-binding protein | | 著者 | Lu, X, Ghimire-Rijal, S, Myles, D.A.A, Cuneo, M.J. | | 登録日 | 2016-01-15 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Periplasmic Binding Protein Dimer Has a Second Allosteric Event Tied to Ligand Binding.
Biochemistry, 56, 2017
|
|
4PFU
 | | Crystal structure of mannobiose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1226) from THERMOTOGA MARITIMA at 2.05 A resolution | | 分子名称: | ABC transporter substrate-binding protein, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Lu, X, Ghimire-Rijal, S, Cuneo, M.J. | | 登録日 | 2014-04-30 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | | 主引用文献 | Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity.
J.Biol.Chem., 289, 2014
|
|
4PFW
 | | Crystal structure of mannohexaose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1226) from THERMOTOGA MARITIMA at 2.2 A resolution | | 分子名称: | ABC transporter substrate-binding protein, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Lu, X, Ghimire-Rijal, S, Cuneo, M.J. | | 登録日 | 2014-04-30 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity.
J.Biol.Chem., 289, 2014
|
|
4PFY
 | | Crystal structure of mannohexaose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1223) from THERMOTOGA MARITIMA at 1.5 A resolution | | 分子名称: | ABC transporter substrate-binding protein, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Lu, X, Ghimire-Rijal, S, Cuneo, M.J. | | 登録日 | 2014-05-01 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity.
J.Biol.Chem., 289, 2014
|
|
4PFT
 | | Crystal structure of mannobiose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1223) from THERMOTOGA MARITIMA at 1.75 A resolution | | 分子名称: | ABC transporter substrate-binding protein, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Lu, X, Ghimire-Rijal, S, Cuneo, M.J. | | 登録日 | 2014-04-30 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | | 主引用文献 | Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity.
J.Biol.Chem., 289, 2014
|
|
