1B9Y
 
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1JJ7
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6D9W
 | | Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter, in the inward-open apo state | | Descriptor: | Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ... | | Authors: | Gaudet, R, Bane, L.B, Weihofen, W.A, Singharoy, A, Zimanyi, C.M, Bozzi, A.T. | | Deposit date: | 2018-04-30 | | Release date: | 2019-02-13 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (3.941 Å) | | Cite: | Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter.
Elife, 8, 2019
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1B9X
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2TRC
 | | PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX | | Descriptor: | GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN | | Authors: | Gaudet, R, Bohm, A, Sigler, P.B. | | Deposit date: | 1997-01-06 | | Release date: | 1997-06-05 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
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2PNN
 | | Crystal Structure of the Ankyrin Repeat Domain of Trpv1 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transient receptor potential cation channel subfamily V member 1 | | Authors: | Jin, X, Gaudet, R. | | Deposit date: | 2007-04-24 | | Release date: | 2007-07-03 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity.
Neuron, 54, 2007
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6MEQ
 | | PcdhgB3 EC1-4 in 50 mM HEPES | | Descriptor: | CALCIUM ION, Protocadherin gamma-B3 | | Authors: | Nicoludis, J.M, Gaudet, R. | | Deposit date: | 2018-09-06 | | Release date: | 2019-09-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7UL6
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6ORR
 | | Co-crystal structure of human NicotinamideN-Methyltransferase (NNMT) in complex with High-Affinity Alkynyl Bisubstrate Inhibitor NS1 | | Descriptor: | 9-{9-amino-6-[(3-carbamoylphenyl)ethynyl]-5,6,7,8,9-pentadeoxy-D-glycero-alpha-L-talo-decofuranuronosyl}-9H-purin-6-amine, GLYCEROL, NNMT protein | | Authors: | May, E.J, Policarpo, R.L, Gaudet, R. | | Deposit date: | 2019-04-30 | | Release date: | 2019-10-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | High-Affinity Alkynyl Bisubstrate Inhibitors of NicotinamideN-Methyltransferase (NNMT).
J.Med.Chem., 62, 2019
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8VC2
 | | CryoEM structure of insect gustatory receptor BmGr9 in the presence of fructose | | Descriptor: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, Gustatory receptor | | Authors: | Frank, H.M, Walsh Jr, R.M, Garrity, P.A, Gaudet, R. | | Deposit date: | 2023-12-13 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Structure of an insect gustatory receptor.
Biorxiv, 2023
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8VC1
 | | CryoEM structure of insect gustatory receptor BmGr9 | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, ... | | Authors: | Frank, H.M, Walsh Jr, R.M, Garrity, P.A, Gaudet, R. | | Deposit date: | 2023-12-13 | | Release date: | 2024-01-10 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Structure of an insect gustatory receptor.
Biorxiv, 2023
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4K8O
 | | CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Antigen peptide transporter 1, CITRIC ACID, ... | | Authors: | Vakkasoglu, A.S, Grossmann, N, Hulpke, S, Abele, R, Tampe, R, Gaudet, R. | | Deposit date: | 2013-04-18 | | Release date: | 2014-09-03 | | Last modified: | 2014-12-03 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
Nat Commun, 5, 2014
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6MER
 | | PcdhgB3 EC1-4 in 50 mM HEPES | | Descriptor: | CALCIUM ION, Protocadherin gamma-B3 | | Authors: | Nicoludis, J.M, Gaudet, R. | | Deposit date: | 2018-09-06 | | Release date: | 2019-09-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7MDC
 | | Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid | | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... | | Authors: | Velilla, J.A, Volpe, M.R, Gaudet, R. | | Deposit date: | 2021-04-03 | | Release date: | 2022-09-28 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A small molecule inhibitor prevents gut bacterial genotoxin production.
Nat.Chem.Biol., 19, 2023
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7MDE
 | | Full-length S95A ClbP | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... | | Authors: | Velilla, J.A, Volpe, M.R, Gaudet, R. | | Deposit date: | 2021-04-04 | | Release date: | 2022-09-28 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of colibactin activation by the ClbP peptidase.
Nat.Chem.Biol., 19, 2023
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7MDF
 | | Full-length S95A ClbP bound to N-acyl-D-asparagine analog | | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... | | Authors: | Velilla, J.A, Volpe, M.R, Gaudet, R. | | Deposit date: | 2021-04-04 | | Release date: | 2022-09-28 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis of colibactin activation by the ClbP peptidase.
Nat.Chem.Biol., 19, 2023
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5UCG
 | | Structure of the PP2C Phosphatase Domain and a Fragment of the Regulatory Domain of the Cell Fate Determinant SpoIIE from Bacillus Subtilis | | Descriptor: | Stage II sporulation protein E | | Authors: | Bradshaw, N, Levdikov, V, Zimanyi, C, Gaudet, R, Wilkinson, A, Losick, R. | | Deposit date: | 2016-12-22 | | Release date: | 2017-05-31 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.906 Å) | | Cite: | A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
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2ETC
 | | Crystal structure of the ankyrin repeat domain of TRPV2 | | Descriptor: | Transient receptor potential cation channel subfamily V member 2 | | Authors: | Jin, X, Gaudet, R. | | Deposit date: | 2005-10-27 | | Release date: | 2006-06-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of the N-terminal Ankyrin Repeat Domain of the TRPV2 Ion Channel.
J.Biol.Chem., 281, 2006
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1XD3
 | | Crystal structure of UCHL3-UbVME complex | | Descriptor: | MAGNESIUM ION, METHYL 4-AMINOBUTANOATE, UBC protein, ... | | Authors: | Misaghi, S, Galardy, P.J, Meester, W.J.N, Ovaa, H, Ploegh, H.L, Gaudet, R. | | Deposit date: | 2004-09-03 | | Release date: | 2004-11-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J.Biol.Chem., 280, 2005
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4WAI
 | | Structural characterization of the late competence protein ComFB from Bacillus subtilis. | | Descriptor: | ComF operon protein 2, ZINC ION | | Authors: | Sysoeva, T.A, Bane, L.B, Xiao, D, Gaudet, R, Burton, B.M. | | Deposit date: | 2014-08-29 | | Release date: | 2014-12-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.427 Å) | | Cite: | Structural characterization of the late competence protein ComFB from Bacillus subtilis.
Biosci.Rep., 35, 2015
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3SUI
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3JXJ
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3JXI
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5K8R
 | | Structure of human clustered protocadherin gamma B3 EC1-4 | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Nicoludis, J.M, Vogt, B.E, Gaudet, R. | | Deposit date: | 2016-05-30 | | Release date: | 2016-08-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4.
Elife, 5, 2016
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5KTE
 | | Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter | | Descriptor: | Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ... | | Authors: | Bane, L.B, Gaudet, R, Weihofen, W.A, Singharoy, A. | | Deposit date: | 2016-07-11 | | Release date: | 2016-11-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.941 Å) | | Cite: | Crystal Structure and Conformational Change Mechanism of a Bacterial Nramp-Family Divalent Metal Transporter.
Structure, 24, 2016
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