1YPY
| Crystal Structure of Vaccinia Virus L1 protein | Descriptor: | Virion membrane protein | Authors: | Su, H.P, Garman, S.C, Allison, T.J, Fogg, C, Moss, B, Garboczi, D.N. | Deposit date: | 2005-01-31 | Release date: | 2005-03-01 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies. Proc.Natl.Acad.Sci.Usa, 102, 2005
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3LX9
| Interconversion of Human Lysosomal Enzyme Specificities | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | Authors: | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | Deposit date: | 2010-02-25 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3LXA
| Interconversion of Human Lysosomal Enzyme Specificities | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | Authors: | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | Deposit date: | 2010-02-25 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3LXC
| Interconversion of Human Lysosomal Enzyme Specificities | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... | Authors: | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | Deposit date: | 2010-02-25 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3LXB
| Interconversion of Human Lysosomal Enzyme Specificities | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | Authors: | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | Deposit date: | 2010-02-25 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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7KL2
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7KL1
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | Authors: | Ozden, C, Stratton, M.M, Garman, S.C. | Deposit date: | 2020-10-28 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7KL0
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) | Descriptor: | 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... | Authors: | Ozden, C, Stratton, M.M, Garman, S.C. | Deposit date: | 2020-10-28 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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5KZX
| Crystal structure of human GAA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Deming, D.T, Garman, S.C. | Deposit date: | 2016-07-25 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of human GAA: structural basis of Pompe disease To be published
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5KZW
| Crystal structure of human GAA | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Deming, D.T, Garman, S.C. | Deposit date: | 2016-07-25 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of human GAA: structural basis of Pompe disease To be published
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7UIR
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and Tiam1 in complex with ATP | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | Authors: | Ozden, C, Stratton, M.M, Garman, S.C. | Deposit date: | 2022-03-29 | Release date: | 2022-04-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7UIQ
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7UIS
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7UJT
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, ... | Authors: | Ozden, C, Stratton, M.M, Garman, S.C. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7UJR
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | Descriptor: | 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... | Authors: | Ozden, C, Santos, N.J, Stratton, M.M, Garman, S.C. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7UJS
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... | Authors: | Ozden, C, Santos, N.J, Stratton, M.M, Garman, S.C. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7UJQ
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | Descriptor: | Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, Glutamate receptor ionotropic, ... | Authors: | Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7UJP
| Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | Authors: | Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
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7URW
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7URZ
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4DO6
| Pharmacological chaperones for human alpha-N-acetylgalactosaminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminidase, ... | Authors: | Clark, N.E, Garman, S.C. | Deposit date: | 2012-02-09 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Pharmacological chaperones for human alpha-N-acetylgalactosaminidase Proc.Natl.Acad.Sci.USA, 109, 2012
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4DO4
| Pharmacological chaperones for human alpha-N-acetylgalactosaminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | Authors: | Clark, N.E, Garman, S.C. | Deposit date: | 2012-02-09 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Pharmacological chaperones for human alpha-N-acetylgalactosaminidase Proc.Natl.Acad.Sci.USA, 109, 2012
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4DO5
| Pharmacological chaperones for human alpha-N-acetylgalactosaminidase | Descriptor: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Clark, N.E, Garman, S.C. | Deposit date: | 2012-02-09 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Pharmacological chaperones for human alpha-N-acetylgalactosaminidase Proc.Natl.Acad.Sci.USA, 109, 2012
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4FDJ
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4FDI
| The molecular basis of mucopolysaccharidosis IV A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CITRIC ACID, ... | Authors: | Rivera-Colon, Y, Garman, S.C. | Deposit date: | 2012-05-28 | Release date: | 2012-09-05 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A. J.Mol.Biol., 423, 2012
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