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7UJR

Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B

Replaces:  6XDL
Summary for 7UJR
Entry DOI10.2210/pdb7ujr/pdb
Related6x5g
DescriptorCalcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, NMDA 2B, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordscamkii, kinase, human, camk2a, transferase
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight33585.50
Authors
Ozden, C.,Santos, N.J.,Stratton, M.M.,Garman, S.C. (deposition date: 2022-03-31, release date: 2022-04-13, Last modification date: 2023-10-18)
Primary citationOzden, C.,Sloutsky, R.,Mitsugi, T.,Santos, N.,Agnello, E.,Gaubitz, C.,Foster, J.,Lapinskas, E.,Esposito, E.A.,Saneyoshi, T.,Kelch, B.A.,Garman, S.C.,Hayashi, Y.,Stratton, M.M.
CaMKII binds both substrates and activators at the active site.
Cell Rep, 40:111064-111064, 2022
Cited by
PubMed: 35830796
DOI: 10.1016/j.celrep.2022.111064
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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