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7UJR

Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B

Replaces:  6XDL
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACalcium/calmodulin-dependent protein kinase type II subunit alphapolymer26830549.11UniProt (Q9UQM7)
Pfam (PF00069)
In PDB
Homo sapiens (human)CaMK-II subunit alpha
2BGlutamate receptor ionotropic, NMDA 2Bpolymer222754.21UniProt (Q13224)
In PDB
Homo sapiensGluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NR2B,N-methyl-D-aspartate receptor subunit 3,hNR3
3A, B1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4ASULFATE IONnon-polymer96.11Chemie (SO4)
5waterwater18.093Chemie (HOH)
Sequence modifications
A: 7 - 274 (UniProt: Q9UQM7)
PDBExternal DatabaseDetails
Lys 223Gln 223engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight33303.2
Non-Polymers*Number of molecules4
Total formula weight282.3
All*Total formula weight33585.5
*Water molecules are not included.

223166

PDB entries from 2024-07-31

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