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PDB: 478 件
5GRJ
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Crystal structure of human PD-L1 with monoclonal antibody avelumab
分子名称: Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain
著者Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F.
登録日2016-08-11
公開日2016-11-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.206 Å)
主引用文献Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
5XJ4
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Complex structure of durvalumab-scFv/PD-L1
分子名称: Programmed cell death 1 ligand 1, durvalumab-VH, durvalumab-VL
著者Tan, S, Liu, K, Chai, Y, Gao, G.F, Qi, J.
登録日2017-04-29
公開日2018-04-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab
Protein Cell, 9, 2018
5H3X
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BU of 5h3x by Molmil
The structure of the N-terminal of the fibronectin/fibrinogen-binding protein from Streptococcus suis (FBPS)
分子名称: Fibronectin/fibrinogen binding protein
著者MokiMusyoki, A, Qi, J, Gao, G.F.
登録日2016-10-27
公開日2016-11-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and functional analysis of an anchorless fibronectin-binding protein FBPS from Gram-positive bacterium Streptococcus suis
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4G42
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Structure of the Chicken MHC Class I Molecule BF2*0401 complexed to pepitde P8D
分子名称: 8-MERIC PEPTIDE P8D, Beta-2 microglobulin, MHC class I alpha chain 2
著者Zhang, J, Chen, Y, Qi, J, Gao, F, Liu, J, Kaufman, J, Xia, C, Gao, G.F.
登録日2012-07-16
公開日2012-11-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
5H3W
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BU of 5h3w by Molmil
The structure of the C-terminal of the fibronectin/fibrinogen-binding protein from Streptococcus suis (FBPS)
分子名称: Fibronectin/fibrinogen binding protein
著者Musyoki, A.M, Qi, J, Gao, G.F.
登録日2016-10-27
公開日2016-11-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional analysis of an anchorless fibronectin-binding protein FBPS from Gram-positive bacterium Streptococcus suis
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4E0R
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BU of 4e0r by Molmil
Structure of the chicken MHC class I molecule BF2*0401
分子名称: 8-MERIC PEPTIDE (FUS/TLS), Beta-2 microglobulin, MHC class I alpha chain 2
著者Zhang, J, Chen, Y, Qi, J, Gao, F, Kaufman, J, Xia, C, Gao, G.F.
登録日2012-03-05
公開日2012-11-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
4F23
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BU of 4f23 by Molmil
Influenza A virus hemagglutinin H16 HA0 structure with an alpha-helix conformation in the cleavage site: a potential drug target
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Lu, X, Shi, Y, Gao, F, Xiao, H, Qi, J, Gao, G.F.
登録日2012-05-07
公開日2012-11-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage.
J.Virol., 86, 2012
4FIU
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The structure of hemagglutinin of H16 subtype influenza virus with V327G mutation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Lu, X, Shi, Y, Gao, F, Xiao, H, Wang, M, Qi, J, Gao, G.F.
登録日2012-06-11
公開日2012-11-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage.
J.Virol., 86, 2012
5XLO
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BU of 5xlo by Molmil
Anti-CRISPR proteins AcrF1/2 bound to Csy surveillance complex with a 32nt spacer crRNA backbone region
分子名称: CRISPR-associated protein Csy3, Uncharacterized protein AcrF1, crRNA with 32nt spacer sequence
著者Peng, R, Shi, Y, Gao, G.F.
登録日2017-05-11
公開日2018-01-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures.
Cell Res., 27, 2017
4G43
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BU of 4g43 by Molmil
Structure of the chicken MHC class I molecule BF2*0401 complexed to P5E
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 8-MERIC PEPTIDE P5E, Beta-2 microglobulin, ...
著者Zhang, J, Chen, Y, Qi, J, Gao, F, Liu, J, Kaufman, J, Xia, C, Gao, G.F.
登録日2012-07-16
公開日2012-11-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
5XLP
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BU of 5xlp by Molmil
Anti-CRISPR proteins AcrF1/2 bound to Csy surveillance complex with a 20nt spacer crRNA backbone region
分子名称: CRISPR-associated protein Csy3, Uncharacterized protein AcrF1, crRNA with 20nt spacer sequence
著者Peng, R, Shi, Y, Gao, G.F.
登録日2017-05-11
公開日2018-01-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures.
Cell Res., 27, 2017
4H32
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BU of 4h32 by Molmil
The crystal structure of the hemagglutinin H17 derived the bat influenza A virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Sun, X, Shi, Y, Lu, X, He, J, Gao, F, Yan, J, Qi, J, Gao, G.F.
登録日2012-09-13
公開日2013-07-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Bat-derived influenza hemagglutinin H17 does not bind canonical avian or human receptors and most likely uses a unique entry mechanism.
Cell Rep, 3, 2013
7XNF
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BU of 7xnf by Molmil
Structure of SARS-CoV-2 antibody P2C-1F11 with GX/P2V/2017 RBD
分子名称: P2C-1F11 Heavy Chain, P2C-1F11 Lambda chain, Spike protein S1
著者Jia, Y.F, Chai, Y, Wang, Q.H, Gao, G.F.
登録日2022-04-28
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017.
Cell Rep, 41, 2022
7WVD
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BU of 7wvd by Molmil
Crystal structure of H14 complexed with SIA28
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ...
著者Chen, Y, Qi, J, Gao, G.F.
登録日2022-02-10
公開日2023-01-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
7WVI
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BU of 7wvi by Molmil
Crystal structure of SIA28
分子名称: Heavy chain of SIA28, Light chain of SIA28
著者Chen, Y, Qi, J, Gao, G.F.
登録日2022-02-10
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
7WVG
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Crystal structure of H18 complexed with SIA28
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ...
著者Chen, Y, Qi, J, Gao, G.F.
登録日2022-02-10
公開日2023-01-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
1WDF
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crystal structure of MHV spike protein fusion core
分子名称: E2 glycoprotein
著者Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z.
登録日2004-05-14
公開日2004-06-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
J.Biol.Chem., 279, 2004
1WDG
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BU of 1wdg by Molmil
crystal structure of MHV spike protein fusion core
分子名称: E2 glycoprotein
著者Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z.
登録日2004-05-14
公開日2004-06-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
J.Biol.Chem., 279, 2004
7XAD
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BU of 7xad by Molmil
Crystal strucutre of PD-L1 and DBL2_02 designed protein binder
分子名称: DBL2_02 binder, Programmed cell death 1 ligand 1
著者Liu, K.F, Xu, Z.P, Han, P, Pacesa, M, Gao, G.F, Chai, Y, Tan, S.G.
登録日2022-03-17
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献De novo design of protein interactions with learned surface fingerprints.
Nature, 617, 2023
1WP8
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crystal structure of Hendra Virus fusion core
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0
著者Xu, Y, Liu, Y, Lou, Z, Su, N, Bai, Z, Gao, G.F, Rao, Z.
登録日2004-08-31
公開日2005-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of Nipah and Hendra virus fusion core proteins
FEBS J., 273, 2006
7XAE
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BU of 7xae by Molmil
Crystal strucutre of PD-L1 and 3ONJA protein
分子名称: 2IC6, Programmed cell death 1 ligand 1
著者Liu, K.F, Xu, Z.P, Han, P, Gao, G.F, Chai, Y, Tan, S.G.
登録日2022-03-17
公開日2023-09-20
実験手法X-RAY DIFFRACTION (3.44 Å)
主引用文献Crystal strucutre of PD-L1 and 2IC6 protein
To Be Published
1WP7
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BU of 1wp7 by Molmil
crystal structure of Nipah Virus fusion core
分子名称: fusion protein
著者Xu, Y, Liu, Y, Lou, Z, Su, N, Bai, Z, Gao, G.F, Rao, Z.
登録日2004-08-31
公開日2005-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Nipah Virus fusion core
To be Published
1WNC
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BU of 1wnc by Molmil
Crystal structure of the SARS-CoV Spike protein fusion core
分子名称: E2 glycoprotein
著者Xu, Y, Lou, Z, Liu, Y, Pang, H, Tien, P, Gao, G.F, Rao, Z.
登録日2004-07-29
公開日2004-09-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core
J.Biol.Chem., 279, 2004
4JU0
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BU of 4ju0 by Molmil
Crystal structure of 2009 pandemic influenza virus hemagglutinin mutant D225E complexed with human receptor analogue LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4JUH
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Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G complexed with avian receptor analogue LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhang, W, Shi, Y, Qi, J, Gao, F, Li, Q, Fan, Z, Yan, J, Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013

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