6KL9
 
 | | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex) | | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | | 登録日 | 2019-07-30 | | 公開日 | 2019-09-11 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4F7T
 | | Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505) | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | | 著者 | Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F. | | 登録日 | 2012-05-16 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
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4HX1
 | | Structure of HLA-A68 complexed with a tumor antigen derived peptide | | 分子名称: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | 登録日 | 2012-11-09 | | 公開日 | 2013-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4HZW
 | | Crystal structure of influenza A neuraminidase N3 complexed with laninamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | | 著者 | Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. | | 登録日 | 2012-11-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
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4HZX
 | | Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. | | 登録日 | 2012-11-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
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4HZZ
 | | Crystal structure of influenza neuraminidase N3-H274Y complexed with oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. | | 登録日 | 2012-11-16 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
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4I00
 | | Crystal structure of influenza A neuraminidase N3-H274Y complexed with zanamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... | | 著者 | Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. | | 登録日 | 2012-11-16 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
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4HZV
 | | The crystal structure of influenza A neuraminidase N3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. | | 登録日 | 2012-11-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
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5YGH
 | | Crystal Structure of the Capsid Protein from Zika Virus | | 分子名称: | Capsid protein | | 著者 | Shang, Z, Song, H, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2017-09-23 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.884 Å) | | 主引用文献 | Crystal Structure of the Capsid Protein from Zika Virus.
J. Mol. Biol., 430, 2018
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8GV6
 | | Crystal structure of PN-SIA28 in complex with influenza hemagglutinin H14 (A/long-tailed duck/Wisconsin/10OS3912/2010) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin H14-HA1, ... | | 著者 | Chen, Y, Song, H, Qi, J, Gao, G.F. | | 登録日 | 2022-09-14 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
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8GRY
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with rat ACE2 (local refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ... | | 著者 | Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F. | | 登録日 | 2022-09-03 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
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7XAE
 | | Crystal strucutre of PD-L1 and 3ONJA protein | | 分子名称: | 2IC6, Programmed cell death 1 ligand 1 | | 著者 | Liu, K.F, Xu, Z.P, Han, P, Gao, G.F, Chai, Y, Tan, S.G. | | 登録日 | 2022-03-17 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | | 主引用文献 | Crystal strucutre of PD-L1 and 2IC6 protein
To Be Published
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6A7W
 | | Structure of a catalytic domain of the colistin resistance enzyme | | 分子名称: | Putative integral membrane protein, ZINC ION | | 著者 | Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F. | | 登録日 | 2018-07-04 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | | 主引用文献 | Structural and functional insights into MCR-2 mediated colistin resistance.
Sci China Life Sci, 61, 2018
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6LGW
 | | Structure of Rabies virus glycoprotein in complex with neutralizing antibody 523-11 at acidic pH | | 分子名称: | Glycoprotein, scFv 523-11 | | 著者 | Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W. | | 登録日 | 2019-12-06 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.9037 Å) | | 主引用文献 | Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
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5XEA
 | | Structure of Thogoto virus envelope glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ... | | 著者 | Peng, R, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2017-04-03 | | 公開日 | 2017-10-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | | 主引用文献 | Structures of human-infecting Thogotovirus fusogens support a common ancestor with insect baculovirus
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6LGX
 | | Structure of Rabies virus glycoprotein at basic pH | | 分子名称: | Glycoprotein,Glycoprotein,Glycoprotein | | 著者 | Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W. | | 登録日 | 2019-12-06 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.097 Å) | | 主引用文献 | Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
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8I5D
 | | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) | | 分子名称: | Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ... | | 著者 | Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F. | | 登録日 | 2023-01-25 | | 公開日 | 2023-08-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
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4H53
 | | Influenza N2-Tyr406Asp neuraminidase in complex with beta-Neu5Ac | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Vavricka, C.J, Liu, Y, Kiyota, H, Sriwilaijaroen, N, Qi, J, Tanaka, K, Wu, Y, Li, Q, Li, Y, Yan, J, Suzuki, Y, Gao, G.F. | | 登録日 | 2012-09-18 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Nat Commun, 4, 2013
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7WVD
 | | Crystal structure of H14 complexed with SIA28 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | | 著者 | Chen, Y, Qi, J, Gao, G.F. | | 登録日 | 2022-02-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
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8GPX
 | | YFV_E_YD73Fab_postfusion | | 分子名称: | Envelope protein, YD73Fab_H, YD73Fab_K | | 著者 | Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
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6KUR
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) | | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | 登録日 | 2019-09-02 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUK
 | | Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1) | | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | 登録日 | 2019-09-02 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUP
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2) | | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | 登録日 | 2019-09-02 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUU
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3) | | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | 登録日 | 2019-09-02 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3)
To Be Published
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6KUV
 | | Structure of influenza D virus polymerase bound to cRNA promoter in class 2 | | 分子名称: | 3'-cRNA, 5'-cRNA, Polymerase 3, ... | | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | 登録日 | 2019-09-02 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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