2WF8
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![BU of 2wf8 by Molmil](/molmil-images/mine/2wf8) | Structure of Beta-Phosphoglucomutase inhibited with Glucose-6- phosphate, Glucose-1-phosphate and Beryllium trifluoride | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, 6-O-phosphono-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Bowler, M.W, Baxter, N.J, Webster, C.E, Pollard, S, Alizadeh, T, Hounslow, A.M, Cliff, M.J, Bermel, W, Williams, N.H, Hollfelder, F, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-04-03 | Release date: | 2010-05-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Near attack conformers dominate beta-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
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2WZB
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![BU of 2wzb by Molmil](/molmil-images/mine/2wzb) | The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP, 3PG and magnesium trifluoride | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hownslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-11-27 | Release date: | 2010-04-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis. J.Am.Chem.Soc., 132, 2010
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2X13
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![BU of 2x13 by Molmil](/molmil-images/mine/2x13) | The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP and 3phosphoglycerate | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hownslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-12-21 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation with Ground State Analogues To be Published
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2X15
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![BU of 2x15 by Molmil](/molmil-images/mine/2x15) | The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP and 1,3- bisphosphoglycerate | Descriptor: | 1,3-BISPHOSPHOGLYCERIC ACID, 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hounslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-12-21 | Release date: | 2011-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analoges To be Published
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2WZC
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![BU of 2wzc by Molmil](/molmil-images/mine/2wzc) | The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP, 3PG and aluminium tetrafluoride | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hownslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-11-27 | Release date: | 2010-04-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis. J.Am.Chem.Soc., 132, 2010
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2X14
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![BU of 2x14 by Molmil](/molmil-images/mine/2x14) | The catalytically active fully closed conformation of human phosphoglycerate kinase K219A mutant in complex with AMP-PCP and 3PG | Descriptor: | 3-PHOSPHOGLYCERIC ACID, MAGNESIUM ION, PHOSPHOGLYCERATE KINASE 1, ... | Authors: | Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hownslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-12-21 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analogues To be Published
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2WFA
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![BU of 2wfa by Molmil](/molmil-images/mine/2wfa) | Structure of Beta-Phosphoglucomutase inhibited with Beryllium trifluoride, in an open conformation. | Descriptor: | BERYLLIUM TRIFLUORIDE ION, BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION | Authors: | Bowler, M.W, Baxter, N.J, Webster, C.E, Pollard, S, Alizadeh, T, Hounslow, A.M, Cliff, M.J, Bermel, W, Williams, N.H, Hollfelder, F, Blackburn, G.M, Waltho, J.P. | Deposit date: | 2009-04-03 | Release date: | 2010-05-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Near Attack Conformers Dominate Beta-Phosphoglucomutase Complexes Where Geometry and Charge Distribution Reflect Those of Substrate. Proc.Natl.Acad.Sci.USA, 109, 2012
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2XDF
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![BU of 2xdf by Molmil](/molmil-images/mine/2xdf) | Solution Structure of the Enzyme I Dimer Complexed with HPr Using Residual Dipolar Couplings and Small Angle X-Ray Scattering | Descriptor: | PHOSPHOCARRIER PROTEIN HPR, PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE | Authors: | Schwieters, C.D, Suh, J.-Y, Grishaev, A, Guirlando, R, Takayama, Y, Clore, G.M. | Deposit date: | 2010-04-30 | Release date: | 2010-09-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Solution Structure of the 128 kDa Enzyme I Dimer from Escherichia Coli and its 146 kDa Complex with Hpr Using Residual Dipolar Couplings and Small- and Wide-Angle X-Ray Scattering. J.Am.Chem.Soc., 132, 2010
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2Y8N
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![BU of 2y8n by Molmil](/molmil-images/mine/2y8n) | Crystal structure of glycyl radical enzyme | Descriptor: | 4-HYDROXYPHENYLACETATE DECARBOXYLASE LARGE SUBUNIT, 4-HYDROXYPHENYLACETATE DECARBOXYLASE SMALL SUBUNIT, IRON/SULFUR CLUSTER | Authors: | Martins, B.M, Blaser, M, Feliks, M, Ullmann, G.M, Selmer, T. | Deposit date: | 2011-02-08 | Release date: | 2011-09-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for a Kolbe-Type Decarboxylation Catalyzed by a Glycyl Radical Enzyme. J.Am.Chem.Soc., 133, 2011
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1U12
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![BU of 1u12 by Molmil](/molmil-images/mine/1u12) | M. loti cyclic nucleotide binding domain mutant | Descriptor: | IODIDE ION, POTASSIUM ION, SULFATE ION, ... | Authors: | Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. | Deposit date: | 2004-07-14 | Release date: | 2004-11-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel Cell(Cambridge,Mass.), 119, 2004
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1RZY
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![BU of 1rzy by Molmil](/molmil-images/mine/1rzy) | Crystal structure of rabbit Hint complexed with N-ethylsulfamoyladenosine | Descriptor: | 5'-O-(N-ETHYL-SULFAMOYL)ADENOSINE, Histidine triad nucleotide-binding protein 1 | Authors: | Krakowiak, A.K, Pace, H.C, Blackburn, G.M, Adams, M, Mekhalfia, A, Kaczmarek, R, Baraniak, J, Stec, W.J, Brenner, C. | Deposit date: | 2003-12-29 | Release date: | 2004-03-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors J.Biol.Chem., 279, 2004
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1UNJ
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![BU of 1unj by Molmil](/molmil-images/mine/1unj) | Crystal structure of a 7-Aminoactinomycin D complex with non-complementary DNA | Descriptor: | 5'-D(*TP*TP*AP*GP*BRU*TP)-3', 7-AMINO-ACTINOMYCIN D | Authors: | Alexopoulos, E.C, Klement, R, Jares-Erijman, E.A, Uson, I, Jovin, T.M, Sheldrick, G.M. | Deposit date: | 2003-09-10 | Release date: | 2004-12-16 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal and Solution Structures of 7-Amino-Actinomycin D Complexes with D(Ttagbrut), D(Ttagtt) and D(Tttagttt) Acta Crystallogr.,Sect.D, 61, 2005
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1RYJ
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![BU of 1ryj by Molmil](/molmil-images/mine/1ryj) | Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526. | Descriptor: | unknown | Authors: | Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-22 | Release date: | 2004-02-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | AN NMR APPROACH TO STRUCTURAL PROTEOMICS Proc.Natl.Acad.Sci.USA, 99, 2002
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1SHO
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![BU of 1sho by Molmil](/molmil-images/mine/1sho) | |
1UNM
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![BU of 1unm by Molmil](/molmil-images/mine/1unm) | Crystal structure of 7-Aminoactinomycin D with non-complementary DNA | Descriptor: | 5'-D(*TP*TP*AP*GP*BRU*TP)-3', 7-AMINOACTINOMYCIN D | Authors: | Alexopoulos, E.C, Klement, R, Jares-Erijman, E.A, Uson, I, Jovin, T.M, Sheldrick, G.M. | Deposit date: | 2003-09-11 | Release date: | 2004-09-24 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal and Solution Structures of 7-Amino-Actinomycin D Complexes with D(Ttagbrut), D(Ttagtt) and D(Tttagttt) Acta Crystallogr.,Sect.D, 61, 2005
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1UNO
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![BU of 1uno by Molmil](/molmil-images/mine/1uno) | Crystal structure of a d,l-alternating peptide | Descriptor: | H-(L-TYR-D-TYR)4-LYS-OH | Authors: | Alexopoulos, E, Kuesel, A, Uson, I, Diederichsen, U, Sheldrick, G.M. | Deposit date: | 2003-09-11 | Release date: | 2004-09-24 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Solution and Structure of an Alternating D,L-Peptide Acta Crystallogr.,Sect.D, 60, 2004
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1VCJ
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![BU of 1vcj by Molmil](/molmil-images/mine/1vcj) | Influenza B virus neuraminidase complexed with 1-(4-Carboxy-2-(3-pentylamino)phenyl)-5-aminomethyl-5-hydroxymethyl-pyrrolidin-2-one | Descriptor: | 4-[(2R)-2-(AMINOMETHYL)-2-(HYDROXYMETHYL)-5-OXOPYRROLIDIN-1-YL]-3-[(1-ETHYLPROPYL)AMINO]BENZOIC ACID, NEURAMINIDASE | Authors: | Lommer, B.S, Ali, S.M, Bajpai, S.N, Brouillette, W.J, Air, G.M, Luo, M. | Deposit date: | 2004-03-09 | Release date: | 2004-03-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase. Acta Crystallogr.,Sect.D, 60, 2004
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1VKR
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1VMC
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![BU of 1vmc by Molmil](/molmil-images/mine/1vmc) | STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA) | Descriptor: | Stromal cell-derived factor 1 | Authors: | Gozansky, E.K, Clore, G.M. | Deposit date: | 2004-09-20 | Release date: | 2005-03-01 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha. J.Mol.Biol., 345, 2005
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1VP6
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![BU of 1vp6 by Molmil](/molmil-images/mine/1vp6) | M.loti ion channel cylic nucleotide binding domain | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel | Authors: | Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. | Deposit date: | 2004-10-14 | Release date: | 2004-10-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell(Cambridge,Mass.), 119, 2004
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1W7Q
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![BU of 1w7q by Molmil](/molmil-images/mine/1w7q) | Feglymycin P65 crystal form | Descriptor: | 1,2-ETHANEDIOL, ETHANOL, FEGLYMYCIN | Authors: | Bunkoczi, G, Vertesy, L, Sheldrick, G.M. | Deposit date: | 2004-09-08 | Release date: | 2005-03-08 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | The Antiviral Antibiotic Feglymycin: First Direct Methods Solution of a 1000Plus Equal-Atom Structure Angew.Chem.Int.Ed.Engl., 44, 2005
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1W7R
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![BU of 1w7r by Molmil](/molmil-images/mine/1w7r) | Feglymycin P64 crystal form | Descriptor: | CITRATE ANION, FEGLYMYCIN, ISOPROPYL ALCOHOL | Authors: | Bunkoczi, G, Vertesy, L, Sheldrick, G.M. | Deposit date: | 2004-09-08 | Release date: | 2005-03-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Antiviral Antibiotic Feglymycin: First Direct Methods Solution of a 1000Plus Equal-Atom Structure Angew.Chem.Int.Ed.Engl., 44, 2005
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1VRC
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1VRV
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1WJB
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![BU of 1wjb by Molmil](/molmil-images/mine/1wjb) | SOLUTION STRUCTURE OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE (D FORM), NMR, 40 STRUCTURES | Descriptor: | HIV-1 INTEGRASE, ZINC ION | Authors: | Clore, G.M, Cai, M, Caffrey, M, Gronenborn, A.M. | Deposit date: | 1997-05-13 | Release date: | 1998-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal zinc binding domain of HIV-1 integrase. Nat.Struct.Biol., 4, 1997
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