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PDB: 1718 件

6OWO
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CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G.
登録日2019-05-10
公開日2019-09-11
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex.
Elife, 8, 2019
6OQZ
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Crystal structure of Glucose Isomerase from Non-merohedrally twinned crystals
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R.
登録日2019-04-29
公開日2019-12-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Non-merohedral twinning: from minerals to proteins.
Acta Crystallogr D Struct Biol, 75, 2019
6BAA
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Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Martin, G.M, Yoshioka, C, Shyng, S.L.
登録日2017-10-12
公開日2017-11-01
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM.
Elife, 6, 2017
6B9C
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Superfolder Green Fluorescent Protein with 4-nitro-L-phenylalanine at the chromophore (position 66)
分子名称: CARBON DIOXIDE, Green fluorescent protein
著者Phillips-Piro, C.M, Brewer, S.H, Olenginski, G.M, Piacentini, J.
登録日2017-10-10
公開日2018-10-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Structural and spectrophotometric investigation of two unnatural amino-acid altered chromophores in the superfolder green fluorescent protein
Acta Crystallogr.,Sect.D, 2021
6BDO
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BU of 6bdo by Molmil
Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with a quinone inhibitor HQNO at 2.8A resolution
分子名称: 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
著者Cook, G.M, Aragao, D, Nakatani, Y.
登録日2017-10-23
公開日2018-05-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors.
Biochim. Biophys. Acta, 1859, 2018
6ARQ
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Crystal structure of CD96 (D1) bound to CD155/necl-5 (D1-3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, T-cell surface protein tactile, ...
著者Deuss, F.A, Watson, G.M, Rossjohn, J, Berry, R.
登録日2017-08-23
公開日2018-11-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Structure, 27, 2019
6PZB
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Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state
分子名称: ATP-binding cassette sub-family C member 8
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZI
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Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6PZA
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Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6BJX
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Group I self-splicing intron P4-P6 domain mutant U131A (with isopropanol soaking)
分子名称: Group I self-splicing intron P4-P6 domain, MAGNESIUM ION
著者Shoffner, G.M.
登録日2017-11-07
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6PZ9
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Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ...
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6C44
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Zika virus capsid protein
分子名称: Capsid protein
著者Morando, M.A, Barbosa, G.M, Cruz-Oliveira, C, Da Poian, A.T, Almeida, F.C.L.
登録日2018-01-11
公開日2019-01-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dynamics of Zika Virus Capsid Protein in Solution: The Properties and Exposure of the Hydrophobic Cleft Are Controlled by the alpha-Helix 1 Sequence.
Biochemistry, 58, 2019
6PZC
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BU of 6pzc by Molmil
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to carbamazepine
分子名称: ATP-binding cassette sub-family C member 8
著者Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日2019-07-31
公開日2019-08-14
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
6D8M
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BU of 6d8m by Molmil
Group I self-splicing intron P4-P6 domain mutant A125U/G126U
分子名称: Group I self-splicing intron, MAGNESIUM ION
著者Shoffner, G.M.
登録日2018-04-26
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
6N8C
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BU of 6n8c by Molmil
Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR
分子名称: Huntingtin
著者Schwieters, C.D, Kotler, S.A, Schmidt, T, Ceccon, A, Ghirlando, R, Libich, D.S, Clore, G.M.
登録日2018-11-29
公開日2019-02-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3EZB
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BU of 3ezb by Molmil
COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI
分子名称: PROTEIN (PHOSPHOCARRIER PROTEIN HPR), PROTEIN (PHOSPHOTRANSFER SYSTEM, ENZYME I)
著者Clore, G.M, Garrett, D.S, Gronenborn, A.M.
登録日1998-11-03
公開日1999-12-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999
3EZE
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BU of 3eze by Molmil
COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE
分子名称: PHOSPHITE ION, PROTEIN (PHOSPHOTRANSFERASE SYSTEM, ENZYME I), ...
著者Clore, G.M, Garrett, D.S, Gronenborn, A.M.
登録日1998-11-04
公開日1998-12-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999
3EZA
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BU of 3eza by Molmil
COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE
分子名称: HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR, PHOSPHOTRANSFERASE SYSTEM, ENZYME I
著者Clore, G.M, Garrett, D.S, Gronenborn, A.M.
登録日1998-11-03
公開日1999-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999
7P9D
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BU of 7p9d by Molmil
Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
著者Singh, R.K, Marchetti, G.M, Hippler, M, Kuemmel, D.
登録日2021-07-27
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
7P49
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HLA-E*01:03 in complex with Mtb14
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Walters, L.C, Gillespie, G.M.
登録日2021-07-10
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
7P4B
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HLA-E*01:03 in complex with IL9
分子名称: Beta-2-microglobulin, ESAT-6-like protein EsxH, GLYCEROL, ...
著者Walters, L.C, Gillespie, G.M.
登録日2021-07-10
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
3IF6
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Crystal structure of OXA-46 beta-lactamase from P. aeruginosa
分子名称: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, L(+)-TARTARIC ACID, ...
著者Docquier, J.D, Benvenuti, M, Calderone, V, Giuliani, F, Kapetis, D, De Luca, F, Rossolini, G.M, Mangani, S.
登録日2009-07-24
公開日2010-03-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates
Antimicrob.Agents Chemother., 54, 2010
7PPZ
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Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form A
分子名称: Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I
著者Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W.
登録日2021-09-15
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
7PQ0
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Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B
分子名称: Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I
著者Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W.
登録日2021-09-15
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
7R94
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T-Plastin-F-actin complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Mei, L, Alushin, G.M.
登録日2021-06-28
公開日2022-07-06
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022

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件を2024-07-10に公開中

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