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PDB: 2224 件

1XTP
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Structural Analysis of Leishmania major LMAJ004091AAA, a SAM-dependent methyltransferase of the DUF858/Pfam05891 family
分子名称: LMAJ004091AAA, S-ADENOSYL-L-HOMOSELENOCYSTEINE
著者Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-10-22
公開日2004-11-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Analysis of Leishmania major LMAJ004091AAA
To be Published
6Q9P
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Crystal structure of human Arginase-1 at pH 9.0 in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ...
著者Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R.
登録日2018-12-18
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X, 4, 2020
5TQU
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor
分子名称: 2-[2-[[3-(1~{H}-benzimidazol-2-ylamino)propylamino]methyl]-4,6-bis(chloranyl)indol-1-yl]ethanol, GLYCEROL, METHIONINE, ...
著者Barros-Alvarez, X, Hol, W.G.J.
登録日2016-10-24
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis.
ACS Infect Dis, 3, 2017
1QHO
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FIVE-DOMAIN ALPHA-AMYLASE FROM BACILLUS STEAROTHERMOPHILUS, MALTOSE/ACARBOSE COMPLEX
分子名称: ALPHA-AMYLASE, CALCIUM ION, SULFATE ION, ...
著者Dauter, Z, Dauter, M, Brzozowski, A.M, Christensen, S, Borchert, T.V, Beier, L, Wilson, K.S, Davies, G.J.
登録日1999-05-25
公開日2000-05-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-ray structure of Novamyl, the five-domain "maltogenic" alpha-amylase from Bacillus stearothermophilus: maltose and acarbose complexes at 1.7A resolution.
Biochemistry, 38, 1999
1QB5
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ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
分子名称: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
著者Merritt, E.A, Hol, W.G.J.
登録日1999-04-30
公開日2003-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
1X6O
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Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a
分子名称: DI(HYDROXYETHYL)ETHER, eukaryotic initiation factor 5a
著者Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-08-11
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Analysis of Leishmania braziliensis eukaryotic initiation factor 5a
To be Published
6QAF
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Crystal structure of human Arginase-1 at pH 9.0 in complex with CB-1158/INCB001158
分子名称: Arginase-1, MANGANESE (II) ION, SODIUM ION, ...
著者Grobben, Y, Uitdehaag, J.C.M, Tabak, W.W.A, Zaman, G.J.R.
登録日2018-12-19
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X, 4, 2020
1Z25
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Structure of P.furiosus Argonaute with bound Mn2+
分子名称: Argonaute, MANGANESE (II) ION
著者Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
登録日2005-03-07
公開日2005-04-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1Z26
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Structure of Pyrococcus furiosus Argonaute with bound tungstate
分子名称: Argonaute, TUNGSTATE(VI)ION
著者Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L.
登録日2005-03-07
公開日2005-04-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1RK4
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Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1
分子名称: CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1
著者Littler, D.R, Harrop, S.J, Fairlie, W.D, Brown, L.J, Pankhurst, G.J, Pankhurst, S, DeMaere, M.Z, Campbell, T.J, Bauskin, A.R, Tonini, R, Mazzanti, M, Breit, S.N, Curmi, P.M.
登録日2003-11-20
公開日2003-12-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition
J.Biol.Chem., 279, 2004
1XUP
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ENTEROCOCCUS CASSELIFLAVUS GLYCEROL KINASE COMPLEXED WITH GLYCEROL
分子名称: GLYCEROL, Glycerol kinase
著者Yeh, J.I, Charrier, V, Paulo, J, Hou, L, Darbon, E, Hol, W.G.J, Deutscher, J.
登録日2004-10-26
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of Enterococcal Glycerol Kinase in the Absence and Presence of Glycerol: Correlation of Conformation to Substrate Binding and a Mechanism of Activation by Phosphorylation
Biochemistry, 43, 2004
1Z2N
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Inositol 1,3,4-trisphosphate 5/6-kinase complexed Mg2+/ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, inositol 1,3,4-trisphosphate 5/6-kinase
著者Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H.
登録日2005-03-08
公開日2005-04-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.
Mol.Cell, 18, 2005
6Q92
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Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ...
著者Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R.
登録日2018-12-17
公開日2019-12-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X, 4, 2020
1XWG
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Human GST A1-1 T68E mutant
分子名称: Glutathione S-transferase A1
著者Grahn, E, Jakobsson, E, Gustafsson, A, Novotny, M, Grehn, L, Olin, B, Madsen, D, Wahlberg, M, Mannervik, B, Kleywegt, G.J.
登録日2004-11-01
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006
1Y63
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Initial crystal structural analysis of a probable kinase from Leishmania major Friedlin
分子名称: ADENOSINE-5'-DIPHOSPHATE, BROMIDE ION, Lmaj004144AAA protein, ...
著者Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-12-03
公開日2005-01-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structural analysis of a probable kinase from Leishmania major Friedlin
To be Published
1Y13
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Structural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)
分子名称: 6-pyruvoyl tetrahydropterin synthase, BIOPTERIN, ZINC ION
著者Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-11-17
公開日2005-01-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of Plasmodium falciparum 6-pyruvoyl tetrahydropterin synthase (PTPS)
To be Published
1UHV
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Crystal structure of beta-D-xylosidase from Thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase
分子名称: 1,5-anhydro-2-deoxy-2-fluoro-D-xylitol, Beta-xylosidase
著者Yang, J.K, Yoon, H.J, Ahn, H.J, Il Lee, B, Pedelacq, J.D, Liong, E.C, Berendzen, J, Laivenieks, M, Vieille, C, Zeikus, G.J, Vocadlo, D.J, Withers, S.G, Suh, S.W.
登録日2003-07-11
公開日2003-12-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of beta-D-xylosidase from Thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase.
J.Mol.Biol., 335, 2004
1UP3
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Structure of the endoglucanase Cel6 from Mycobacterium tuberculosis in complex with METHYL-CELLOBIOSYL-4-DEOXY-4-THIO-BETA-D-CELLOBIOSIDE at 1.6 angstrom
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, PUTATIVE CELLULASE CEL6, SULFATE ION, ...
著者Varrot, A, Leydier, S, Pell, G, Gilbert, H.J, Davies, G.J.
登録日2003-09-26
公開日2004-11-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mycobacterium Tuberculosis Strains Possess Functional Cellulases.
J.Biol.Chem., 280, 2005
1UWR
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Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-galactose
分子名称: 2-deoxy-2-fluoro-alpha-D-galactopyranose, ACETATE ION, BETA-GALACTOSIDASE
著者Gloster, T.M, Roberts, S, Ducros, V.M.-A, Perugino, G, Rossi, M, Hoos, R, Moracci, M, Vasella, A, Davies, G.J.
登録日2004-02-11
公開日2004-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural Studies of the Beta-Glycosidase from Sulfolobus Solfataricus in Complex with Covalently and Noncovalently Bound Inhibitors.
Biochemistry, 43, 2004
1UOZ
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Structure of the endoglucanase Cel6 from Mycobacterium tuberculosis in complex with thiocellopentaose at 1.1 angstrom
分子名称: 4-thio-beta-D-glucopyranose, GLYCEROL, PUTATIVE CELLULASE, ...
著者Varrot, A, Leydier, S, Pell, G, Gilbert, H.J, Davies, G.J.
登録日2003-09-26
公開日2004-11-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Mycobacterium Tuberculosis Strains Possess Functional Cellulases.
J.Biol.Chem., 280, 2005
1U8R
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Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions
分子名称: COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ...
著者Wisedchaisri, G, Holmes, R.K, Hol, W.G.J.
登録日2004-08-06
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions.
J.Mol.Biol., 342, 2004
1US3
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Native xylanase10C from Cellvibrio japonicus
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ENDO-BETA-1,4-XYLANASE PRECURSOR, GLYCEROL, ...
著者Pell, G, Szabo, L, Charnock, S.J, Xie, H, Gloster, T.M, Davies, G.J, Gilbert, H.J.
登録日2003-11-17
公開日2003-12-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Biochemical Analysis of Cellvibrio Japonicus Xylanase 10C: How Variation in Substrate-Binding Cleft Influences the Catalytic Profile of Family Gh-10 Xylanases
J.Biol.Chem., 279, 2004
1Y1X
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Structural analysis of a homolog of programmed cell death 6 protein from Leishmania major Friedlin
分子名称: CALCIUM ION, Leishmania Major Homolog of Programmed Cell Death 6 Protein, SULFATE ION
著者Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-11-19
公開日2004-12-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analysis of a homolog of programmed cell death 6 protein from Leishmania major Friedlin
To be Published
1UQZ
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Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with 4-O-methyl glucuronic acid
分子名称: 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, CHLORIDE ION, ENDOXYLANASE, ...
著者Pell, G, Taylor, E.J, Gloster, T.M, Turkenburg, J.P, Fontes, C.M.G.A, Ferreira, L.M.A, Davies, G.J, Gilbert, H.J.
登録日2003-10-24
公開日2003-12-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Mechanisms by which Family 10 Glycoside Hydrolases Bind Decorated Substrates
J.Biol.Chem., 279, 2004
1UP7
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Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.4 Angstrom resolution in the tetragonal form with NAD and glucose-6-phosphate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J.
登録日2003-09-29
公開日2004-11-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Nad+ and Metal-Ion Dependent Hydrolysis by Family 4 Glycosidases: Structural Insight Into Specificity for Phospho-Beta-D-Glucosides
J.Mol.Biol., 346, 2005

224004

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