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PDB: 94 results

6WHR
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BU of 6whr by Molmil
GluN1b-GluN2B NMDA receptor in non-active 2 conformation at 4 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WI1
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BU of 6wi1 by Molmil
GluN1b-GluN2B NMDA receptor in active conformation stabilized by inter-GluN1b-GluN2B subunit cross-linking
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHX
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BU of 6whx by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 2
Descriptor: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHU
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BU of 6whu by Molmil
GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHW
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BU of 6whw by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1
Descriptor: (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHY
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BU of 6why by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 1
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHS
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BU of 6whs by Molmil
GluN1b-GluN2B NMDA receptor in non-active 1 conformation at 3.95 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHV
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BU of 6whv by Molmil
GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 2
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WHT
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BU of 6wht by Molmil
GluN1b-GluN2B NMDA receptor in active conformation at 4.4 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-08-05
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6WI0
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BU of 6wi0 by Molmil
GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 2
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chou, T, Tajima, N, Furukawa, H.
Deposit date:2020-04-08
Release date:2020-07-15
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
6E7W
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BU of 6e7w by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-115
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7S
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BU of 6e7s by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7U
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BU of 6e7u by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-31
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7X
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BU of 6e7x by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-97
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7V
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BU of 6e7v by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-88
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
6E7T
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BU of 6e7t by Molmil
Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor ionotropic, ...
Authors:Regan, M.C, Furukawa, H.
Deposit date:2018-07-27
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Nat Commun, 10, 2019
4NF5
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BU of 4nf5 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and D-AP5
Descriptor: 5-phosphono-D-norvaline, GLYCEROL, GLYCINE, ...
Authors:Jespersen, A, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
4NF8
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BU of 4nf8 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Jespersen, A, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.856 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
4NF6
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BU of 4nf6 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA
Descriptor: (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Jespersen, A, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
4PE5
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BU of 4pe5 by Molmil
Crystal Structure of GluN1a/GluN2B NMDA Receptor Ion Channel
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, ...
Authors:Karakas, E, Furukawa, H.
Deposit date:2014-04-22
Release date:2014-06-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.96 Å)
Cite:Crystal structure of a heterotetrameric NMDA receptor ion channel.
Science, 344, 2014
4NF4
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BU of 4nf4 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with DCKA and glutamate
Descriptor: 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ...
Authors:Annie, J, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
3OEM
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BU of 3oem by Molmil
Crystal structure of GluN2D ligand-binding core in complex with N-methyl-D-aspartate
Descriptor: Glutamate [NMDA] receptor subunit epsilon-4, N-methyl-D-aspartic acid
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3QEL
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BU of 3qel by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with ifenprodil
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, Glutamate [NMDA] receptor subunit epsilon-2, ...
Authors:Karakas, E, Simorowski, N, Furukawa, H.
Deposit date:2011-01-20
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
3QEM
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BU of 3qem by Molmil
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with Ro 25-6981
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, Glutamate [NMDA] receptor subunit epsilon-2, ...
Authors:Karakas, E, Simorowski, N, Furukawa, H.
Deposit date:2011-01-20
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
3OEK
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BU of 3oek by Molmil
Crystal structure of GluN2D ligand-binding core in complex with L-aspartate
Descriptor: ASPARTIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011

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